Search Results - "van Hoffen, Els"

Characterization of the pathophysiological determinants of diarrheagenic Escherichia coli infection using a challenge model in healthy adults by van Hoffen, Els, Mercenier, Annick, Vidal, Karine, Benyacoub, Jalil, Schloesser, Joyce, Kardinaal, Alwine, Lucas-van de Bos, Elly, van Alen, Ingrid, Roggero, Iris, Duintjer, Kim, Berendts, Anneke, Albers, Ruud, Kleerebezem, Michiel, ten Bruggencate, Sandra

“…An experimental human challenge model with an attenuated diarrheagenic Escherichia coli (E. coli) strain has been used in food intervention studies aimed to…”
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Bovine Lactoferrin Enhances TLR7-Mediated Responses in Plasmacytoid Dendritic Cells in Elderly Women: Results From a Nutritional Intervention Study With Bovine Lactoferrin, GOS and Vitamin D by van Splunter, Marloes, Perdijk, Olaf, Fick-Brinkhof, Henriëtte, Feitsma, Anouk L, Floris-Vollenbroek, Esther G, Meijer, Ben, Brugman, Sylvia, Savelkoul, Huub F J, van Hoffen, Els, van Neerven, R J Joost

“…During aging the immune system is dysregulated. Especially plasmacytoid dendritic cells (pDCs) and myeloid DCs (mDCs) have reduced Toll like receptor…”
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Functional role and mechanisms of sialyllactose and other sialylated milk oligosaccharides by Bruggencate, Sandra JM, Bovee‐Oudenhoven, Ingeborg MJ, Feitsma, Anouk L, Hoffen, Els, Schoterman, Margriet HC

“…Human milk is a rich source of oligosaccharides. Acidic oligosaccharides, such as sialyllactose (SL), contain sialic acid (SA) residues. In human milk,…”
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Sensitization to Cor a 9 and Cor a 14 is highly specific for a hazelnut allergy with objective symptoms in Dutch children and adults by Masthoff, Laury J.N., MD, Mattsson, Lars, PhD, Zuidmeer-Jongejan, Laurian, PhD, Lidholm, Jonas, PhD, Andersson, Kerstin, PhD, Akkerdaas, Jaap H., PhD, Versteeg, Serge A., BSc, Garino, Cristiano, PhD, Meijer, Yolanda, MD, Kentie, Petra, NP, Versluis, Astrid, MSc, den Hartog Jager, Constance F., BSc, Bruijnzeel-Koomen, Carla A.F.M., MD, Knulst, André C., MD, van Ree, Ronald, PhD, van Hoffen, Els, PhD, Pasmans, Suzanne G.M.A., MD

“…Background Component-resolved diagnosis has been shown to improve the diagnosis of food allergy. Objective We sought to evaluate whether component-resolved…”
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Study protocol for cholera vaccination as a model to measure the inflammatory response in the gut: A case of modulation with a Lactobacillus plantarum K8 lysate by Park, Min Young, Park, Soo-Yeon, Hartog, Anita, van Hoffen, Els, Kardinaal, Alwine, Kim, Joohee, Choi, Hee Jung, Kwon, Oran, Kim, Ji Yeon

“…It is crucial for human health that the immune system of the gastrointestinal tract works effectively. Dietary modulation is one of the factors that regulate…”
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Plasmacytoid dendritic cell and myeloid dendritic cell function in ageing: A comparison between elderly and young adult women by Splunter, Marloes van, Perdijk, Olaf, Fick-Brinkhof, Henriëtte, Floris-Vollenbroek, Esther G, Meijer, Ben, Brugman, Sylvia, Savelkoul, Huub F J, van Hoffen, Els, Joost van Neerven, R J

“…Ageing is associated with a changing immune system, leading to inflammageing (increased levels of inflammation markers in serum) and immunosenescence (reduced…”
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Chemically modified peanut extract shows increased safety while maintaining immunogenicity by Kleij, Hanneke P. M., Warmenhoven, Hans J. M., Ree, Ronald, Versteeg, Serge A., Pieters, Raymond H. H., Dreskin, Stephen C., Knulst, André C., Hoffen, Els, Opstelten, Dirk Jan E., Koppelman, Stef J., Smit, Joost J.

“…Background Peanuts are most responsible for food‐induced anaphylaxis in adults in developed countries. An effective and safe immunotherapy is urgently needed…”
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Dietary Milk-Fat-Globule Membrane Affects Resistance to Diarrheagenic Escherichia coli in Healthy Adults in a Randomized, Placebo-Controlled, Double-Blind Study by Ten Bruggencate, Sandra J, Frederiksen, Pernille D, Pedersen, Simon M, Floris-Vollenbroek, Esther G, Lucas-van de Bos, Elly, van Hoffen, Els, Wejse, Peter L

“…The milk-fat-globule membrane (MFGM) contains phospholipids and membrane glycoproteins that have been shown to affect pathogen colonization and gut barrier…”
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Comel‐Netherton syndrome: A local skin barrier defect in the absence of an underlying systemic immunodeficiency by Stuvel, Kira, Heeringa, Jorn J., Dalm, Virgil A. S. H., Meijers, Ruud W. J., Hoffen, Els, Gerritsen, Susan A. M., Zelm, Menno C., Pasmans, Suzanne G. M. A.

“…Background Comel‐Netherton syndrome (NS) is a rare autosomal disease, characterized by severe skin disease, hair shaft defects, atopic diathesis, and increased…”
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Mothers’ Breast Milk Composition and Their Respective Infant’s Gut Microbiota Differ between Five Distinct Rural and Urban Regions in Vietnam by Kortman, Guus A. M, Timmerman, Harro M, Schaafsma, Anne, Stoutjesdijk, Eline, Muskiet, Frits A. J, Nhien, Nguyen V, van Hoffen, Els, Boekhorst, Jos, Nauta, Arjen

“…Microbiota colonization and development in early life is impacted by various host intrinsic (genetic) factors, but also diet, lifestyle, as well as…”
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Low doses of diarrhoeagenic E. coli induce enhanced monocyte and mDC responses and prevent development of symptoms after homologous rechallenge by Porbahaie, Mojtaba, van den Belt, Maartje, Ulfman, Laurien, Ruijschop, Rianne M A J, Lucas-van de Bos, Elly, Hartog, Anita, Lenz, Stefanie, van Alen-Boerrigter, Ingrid J, Teodorowicz, Malgorzata, Savelkoul, Huub F J, Calame, Wim, van Hoffen, Els, van Neerven, R J Joost, Kardinaal, Alwine

“…The experimental challenge with attenuated enterotoxigenic E. coli strain E1392/75-2A prevents diarrhea upon a secondary challenge with the same bacteria. A…”
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Peanut epitopes for IgE and IgG4 in peanut-sensitized children in relation to severity of peanut allergy by Flinterman, Annebeth E., MD, Knol, Edward F., PhD, Lencer, Doerthe A., MD, Bardina, Ludmilla, MS, den Hartog Jager, Constance F., BSc, Lin, Jing, PhD, Pasmans, Suzanne G.M.A., MD, PhD, Bruijnzeel-Koomen, Carla A.F.M., MD, PhD, Sampson, Hugh A., MD, van Hoffen, Els, PhD, Shreffler, Wayne G., MD, PhD

“…Background Better understanding of the relationship between antibody response to peanut and clinical sensitivity might lead to more accurate prognostication…”
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A Double-Blind, Randomized Intervention Study on the Effect of a Whey Protein Concentrate on E. coli -Induced Diarrhea in a Human Infection Model by Ulfman, Laurien H, Schloesser, Joyce E L, Kortman, Guus A M, van den Belt, Maartje, Lucas-van de Bos, Elly, Roggekamp, Joris, van Neerven, R J Joost, Porbahaie, Mojtaba, van Hoffen, Els, Kardinaal, Alwine F M

“…Infectious diseases are a major cause of morbidity and mortality worldwide. Nutritional interventions may enhance resistance to infectious diseases or help to…”
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IgG antibodies in food allergy influence allergen-antibody complex formation and binding to B cells: a role for complement receptors by Meulenbroek, Laura A P M, de Jong, Renske J, den Hartog Jager, Constance F, Monsuur, Hanneke N, Wouters, Diana, Nauta, Alma J, Knippels, Léon M J, van Neerven, R J Joost, Ruiter, Bert, Leusen, Jeanette H W, Hack, C Erik, Bruijnzeel-Koomen, Carla A F M, Knulst, André C, Garssen, Johan, van Hoffen, Els

“…Allergen-IgE complexes are more efficiently internalized and presented by B cells than allergens alone. It has been suggested that IgG Abs induced by…”
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Determination of no-observed-adverse-effect levels and eliciting doses in a representative group of peanut-sensitized children by Flinterman, Annebeth E., Pasmans, Suzanne G., Hoekstra, Maarten O., Meijer, Yolanda, van Hoffen, Els, Knol, Edward F., Hefle, Susan L., Bruijnzeel-Koomen, Carla A., Knulst, André C.

“…Current labeling practices for allergenic foods like peanut can be inadequate. For future regulatory and industry guidelines, information on…”
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Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk by van den Elzen, Mignon T., MD, van Os-Medendorp, Harmieke, PhD, Röckmann-Helmbach, Heike, MD, PhD, van Hoffen, Els, PhD, Lebens, Ans F.M., BSc, van Doorn, Helma, BAS, Klemans, Rob J.B., MD, PhD, Bruijnzeel-Koomen, Carla A.F.M., MD, PhD, Hack, C. Erik, PhD, Kaufman, Leonard, PhD, Relan, Anurag, MD, Knulst, André C., MD, PhD

“…Background Recombinant human C1 inhibitor (rhC1INH) for on-demand treatment of hereditary angioedema is purified from milk of transgenic rabbits. It contains…”
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Clustering analyses in peptidomics revealed that peptide profiles of infant formulae are descriptive by Lambers, Tim T., Gloerich, Jolein, Hoffen, Els, Alkema, Wynand, Hondmann, Dirk H., Tol, Eric A.F.

“…Prompted by the accumulating evidence on bioactive moieties of milk‐derived peptides, novel methods were applied to compare the peptide composition among…”
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Differences in the allergenicity of 6 different kiwifruit cultivars analyzed by prick-to-prick testing, open food challenges, and ELISA by Le, Thuy-My, MD, Fritsche, Philipp, MD, Bublin, Merima, PhD, Oberhuber, Christina, PhD, Bulley, Sean, PhD, van Hoffen, Els, PhD, Ballmer-Weber, Barbara K., MD, Knulst, André C., MD, PhD, Hoffmann-Sommergruber, Karin, PhD

“…Symptoms of kiwifruit allergy vary from mild oral symptoms to severe systemic reactions.2 Studies investigating the allergenicity of different kiwifruit…”
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Sensitization to Cor a 9 or Cor a 14 has a strong impact on the distribution of thresholds to hazelnut by Masthoff, Laury J.N., Blom, W. Marty, Rubingh, Carina M., Klemans, Rob J.B., Remington, Ben C., Bruijnzeel-Koomen, Carla A.F.M., van Hoffen, Els, Houben, Geert F., Meyer, Yolanda, Pasmans, Suzanne G.M.A., Knulst, André C.

“…A total of 66 children and 81 adults (see Table E1 in this article's Online Repository at www.jaci-inpractice.org) with a suspicion of hazelnut allergy based…”
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Effect of birch pollen–specific immunotherapy on birch pollen–related hazelnut allergy by van Hoffen, Els, PhD, Peeters, Kim A.B.M., MD, PhD, van Neerven, R.J. Joost, PhD, van der Tas, Corrien W.H., RN, Zuidmeer, Laurian, PhD, van Ieperen-van Dijk, Adrie G., BSc, Bruijnzeel-Koomen, Carla A.F.M., MD, PhD, Knol, Edward F., PhD, van Ree, Ronald, PhD, Knulst, André C., MD, PhD

“…[...]this is not a plausible explanation…”
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