Search Results - "van Herwaarden, A. E."

High fat diet-induced obesity prolongs critical stages of the spermatogenic cycle in a Ldlr−/−.Leiden mouse model by Komninos, D., Ramos, L., van der Heijden, G. W., Morrison, M. C., Kleemann, R., van Herwaarden, A. E., Kiliaan, A. J., Arnoldussen, I. A. C.

“…Obesity can disturb spermatogenesis and subsequently affect male fertility and reproduction. In our study, we aim to elucidate at which cellular level of adult…”
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Gonadal function in adult male patients with congenital adrenal hyperplasia by Engels, M, Gehrmann, K, Falhammar, H, Webb, E A, Nordenström, A, Sweep, F C, Span, P N, van Herwaarden, A E, Rohayem, J, Richter-Unruh, A, Bouvattier, C, Köhler, B, Kortmann, B B, Arlt, W, Roeleveld, N, Reisch, N, Stikkelbroeck, N M M L, Claahsen-van der Grinten, H L

“…Context Current knowledge on gonadal function in congenital adrenal hyperplasia (CAH) is mostly limited to single-center/country studies enrolling small…”
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Impact of nutritional status on vaccine-induced immunity in children living in South Africa: Investigating the B-cell repertoire and metabolic hormones by Mutsaerts, E.A.M.L., van Cranenbroek, B., Madhi, S.A., Simonetti, E., Arns, A.J., Jose, L., Koen, A., van Herwaarden, A.E., de Jonge, M.I., Verhagen, L.M.

“…•Underweight children had decreased antibody response after pneumococcal vaccination.•Specific B-cell subsets were associated with pneumococcal antibody…”
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Effects of daily artificial gravity training on orthostatic tolerance following 60-day strict head-down tilt bedrest by Hoenemann, J.-N., Moestl, S., van Herwaarden, A. E., Diedrich, A., Mulder, E., Frett, T., Petrat, G., Pustowalow, W., Arz, M., Heusser, K., Lee, S., Jordan, J., Tank, J., Hoffmann, F.

“…Purpose Orthostatic intolerance commonly occurs following immobilization or space flight. We hypothesized that daily artificial gravity training through…”
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Adrenal Steroid Metabolites Accumulating in Congenital Adrenal Hyperplasia Lead to Transactivation of the Glucocorticoid Receptor by Pijnenburg-Kleizen, K. J, Engels, M, Mooij, C. F, Griffin, A, Krone, N, Span, P. N, van Herwaarden, A. E, Sweep, F. C. G. J, Claahsen-van der Grinten, H. L

“…Patients with congenital adrenal hyperplasia (CAH) are often clinically less severely affected by cortisol deficiency than anticipated from their enzymatic…”
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Validity of free testosterone calculation in pregnant women by Schuijt, M P, Sweep, C G J, van der Steen, R, Olthaar, A J, Stikkelbroeck, N M M L, Ross, H A, van Herwaarden, A E

“…Objective Increased maternal testosterone concentration during pregnancy may affect the fetus. Therefore it is clinically relevant to have a quick and reliable…”
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Implementing reference systems for thyroid function tests – A collaborative effort by Vesper, H.W., Van Uytfanghe, K., Hishinuma, A., Raverot, V., Patru, M.M., Danilenko, U., van Herwaarden, A.E., Shimizu, E.

“…•IFCC C-STFT is maintaining the reference system for fT4 and TSH.•Implementation activities started in Japan and the US.•IFCC C-STFT survey results on…”
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Saliva oxytocin, cortisol, and testosterone levels in adolescent boys with autism spectrum disorder, oppositional defiant disorder/conduct disorder and typically developing individuals by Bakker-Huvenaars, M.J., Greven, C.U., Herpers, P., Wiegers, E., Jansen, A., van der Steen, R., van Herwaarden, A.E., Baanders, A.N., Nijhof, K.S., Scheepers, F., Rommelse, N., Glennon, J.C., Buitelaar, J.K.

“…The aim of the current study was to compare levels of oxytocin, cortisol, and testosterone in adolescents with either autism spectrum disorder (ASD), or…”
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Longitudinal trends in thyroid function in relation to iodine intake: ongoing changes of thyroid function despite adequate current iodine status by van de Ven, Annenienke C, Netea-Maier, Romana T, Ross, H Alec, van Herwaarden, Teun A E, Holewijn, Suzanne, de Graaf, Jacqueline, Kiemeney, Bart L A, van Tienoven, Doorlène, Wetzels, Jack F M, Smit, Johannes W, Sweep, Fred C G J, Hermus, Ad R M M, den Heijer, Martin

“…ObjectiveSeveral cross-sectional studies on populations with iodine deficiency showed that TSH-levels are negatively associated with age, while in populations…”
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Trends in incidence for gestational trophoblastic disease over the last 20 years in a population-based study by Eysbouts, Y.K, Bulten, J, Ottevanger, P.B, Thomas, C.M.G, ten Kate-Booij, M.J, van Herwaarden, A.E, Siebers, A.G, Sweep, F.C.G.J, Massuger, L.F.A.G

“…Abstract Background Gestational trophoblastic disease (GTD) represents a heterogeneous group of disorders. Wide variations in incidence rates are reported…”
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Plasma steroid profiles before and after ACTH stimulation test in healthy horses by Kirchmeier, A., van Herwaarden, A.E., van der Kolk, J.H., Sauer, F.J., Gerber, V.

“…This study describes steroid profiles in equine plasma before and after ACTH stimulation. In human medicine, other steroids have been shown to have a more…”
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Procollagen‐3 N‐terminal peptide measurements for the detection of liver fibrosis in methotrexate‐treated patients with psoriasis: daily practice use and clinical implications by Reek, J.M.P.A., Menting, S.P., Janssen, W.W.L., Dhaliwal, R., Heijboer, A.C., Herwaarden, A.E., Sweep, F.C.G.J., Jong, L.M., Tjwa, E.T., Otero, M.E., Spuls, P.I., Jong, E.M.G.J.

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Variable workup calls for guideline development for type 2A hereditary haemochromatosis by Smit, S L, Peters, T M A, Gisbertz, I A M, Moolenaar, W, Hendriks, Y, Vincent, H H, Houtsma, D, Loosveld, O J L, van Herwaarden, A E, Rennings, A J M, Swinkels, D W

“…Type 2A hereditary haemochromatosis (type 2A HH) is a rare iron-loading disorder caused by mutations in the HFE2 gene, which encodes the HJV protein. We…”
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Trends in incidence for gestational trophoblastic disease over the last 20years in a population-based study by Eysbouts, Y.K., Bulten, J., Ottevanger, P.B., Thomas, C.M.G., ten Kate-Booij, M.J., van Herwaarden, A.E., Siebers, A.G., Sweep, F.C.G.J., Massuger, L.F.A.G.

“…Gestational trophoblastic disease (GTD) represents a heterogeneous group of disorders. Wide variations in incidence rates are reported worldwide, probably…”
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The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk by Schinkel, Alfred H, Jonker, Johan W, Merino, Gracia, Musters, Sandra, van Herwaarden, Antonius E, Bolscher, Ellen, Wagenaar, Els, Mesman, Elly, Dale, Trevor C

“…Contamination of milk with drugs, pesticides and other xenotoxins can pose a major health risk to breast-fed infants and dairy consumers. Here we show that the…”
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The function of breast cancer resistance protein in epithelial barriers, stem cells and milk secretion of drugs and xenotoxins by van Herwaarden, Antonius E., Schinkel, Alfred H.

“…The breast cancer resistance protein [BCRP (also known as ABCG2)] belongs to the ATP binding cassette (ABC) family of transmembrane drug transporters. BCRP has…”
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The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin by Merino, Gracia, Jonker, Johan W, Wagenaar, Els, van Herwaarden, Antonius E, Schinkel, Alfred H

“…Nitrofurantoin is a commonly used urinary tract antibiotic prescribed to lactating woman. It is actively transported into human and rat milk by an unknown…”
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Breast cancer resistance protein (Bcrp1/Abcg2) reduces systemic exposure of the dietary carcinogens aflatoxin B1, IQ and Trp-P-1 but also mediates their secretion into breast milk by Herwaarden, Antonius E.van, Wagenaar, Els, Karnekamp, Barbara, Merino, Gracia, Jonker, Johan W., Schinkel, Alfred H.

“…The breast cancer resistance protein (BCRP/ABCG2) usually protects the body from a wide variety of environmental and dietary xenotoxins by reducing their net…”
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The breast cancer resistance protein (Bcrp1/Abcg2) restricts exposure to the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by VAN HERWAARDEN, Antonius E, JONKER, Johan W, WAGENAAR, Els, BRINKHUIS, Remco F, SCHELLENS, Jan H. M, BEIJNEN, Jos H, SCHINKEL, Alfred H

“…The food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is the most abundant heterocyclic amine found in various protein containing foods…”
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Sex-dependent expression and activity of the ATP-binding cassette transporter breast cancer resistance protein (BCRP/ABCG2) in liver by Merino, Gracia, van Herwaarden, Antonius E, Wagenaar, Els, Jonker, Johan W, Schinkel, Alfred H

“…The breast cancer resistance protein (BCRP/ABCG2) is an ATP-binding cassette drug efflux transporter present in the liver and other tissues that affects the…”
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