Search Results - "van Harmelen, Joanne"
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The multidimensional legal nature of personal genomic sequence data: A South African perspective
Published in Frontiers in genetics (09-11-2022)“…This article provides a comprehensive analysis of the various dimensions in South African law applicable to personal genomic sequence data. This analysis…”
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2
Broad, high-magnitude and multifunctional CD4+ and CD8+ T-cell responses elicited by a DNA and modified vaccinia Ankara vaccine containing human immunodeficiency virus type 1 subtype C genes in baboons
Published in Journal of general virology (01-02-2009)“…1 Institute of Infectious Disease and Molecular Medicine and Division of Medical Virology, Department of Clinical Laboratory Sciences, Faculty of Health…”
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3
Design and preclinical evaluation of a multigene human immunodeficiency virus type 1 subtype C DNA vaccine for clinical trial
Published in Journal of general virology (01-02-2006)“…1 Institute of Infectious Disease and Molecular Medicine (IIDMM) and Division of Medical Virology, University of Cape Town (UCT), Observatory, Cape Town 7925,…”
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Construction, characterization, and immunogenicity of a multigene modified vaccinia Ankara (MVA) vaccine based on HIV type 1 subtype C
Published in AIDS research and human retroviruses (01-02-2008)“…Candidate vaccines composed of a DNA construct to prime the immune system, followed by modified vaccinia Ankara (MVA) containing matching genes as a booster…”
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A multigene HIV type 1 subtype C modified vaccinia Ankara (MVA) vaccine efficiently boosts immune responses to a DNA vaccine in mice
Published in AIDS research and human retroviruses (01-02-2008)“…Heterologous prime-boost vaccine strategies have generated high frequencies of antigen-specific T cells in preclinical and clinical trials of candidate HIV…”
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Construction and characterisation of a candidate HIV-1 subtype C DNA vaccine for South Africa
Published in Vaccine (01-10-2003)“…A candidate DNA vaccine pTHgagC expressing the immunodeficiency virus-1 (HIV-1) gag gene from South African isolate Du422 was constructed and characterised…”
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Heterosexual transmission of multiple highly conserved viral variants in HIV-1 subtype C-infected seronegative women
Published in AIDS (London) (21-10-2004)“…Viral population diversity was assessed in samples collected from five HIV-infected women who were RNA positive and antibody negative. Similar to studies in…”
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Characterization and selection of HIV-1 subtype C isolates for use in vaccine development
Published in AIDS research and human retroviruses (01-02-2003)“…HIV-1 genetic diversity among circulating strains presents a major challenge for HIV-1 vaccine development, particularly for developing countries where less…”
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HIV type 1 subtype C gag and nef diversity in Southern Africa
Published in AIDS research and human retroviruses (01-03-2007)“…Several HIV-1 subtype C-specific gag- and/or nef-based vaccines are currently intended for clinical trial in southern Africa. Here we provide sequences of 64…”
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HIV-1 subtype C Pr55gag virus-like particle vaccine efficiently boosts baboons primed with a matched DNA vaccine
Published in Journal of general virology (01-09-2008)“…1 Medical Virology, Department of Clinical Laboratory Sciences, Faculty of Health Sciences, University of Cape Town, Rondebosch, Cape Town, South Africa 2…”
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An association between HIV-1 subtypes and mode of transmission in Cape Town, South Africa
Published in AIDS (London) (1997)“…To determine HIV-1 env and gag subtypes in male homosexual and heterosexual populations in Cape Town, South Africa. DNA was isolated from blood originating…”
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Human immunodeficiency virus type 1 subtype C Gag virus-like particle boost substantially improves the immune response to a subtype C gag DNA vaccine in mice
Published in Journal of general virology (01-02-2004)“…1 Department of Molecular and Cell Biology, Faculty of Science, University of Cape Town, Rondebosch 7701, South Africa 2 MRC Liver Research Centre, Department…”
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13
Characterization of full-length HIV type 1 subtype C sequences from South Africa
Published in AIDS research and human retroviruses (01-11-2001)“…Four full-length genome subtype C sequences from South Africa, three of which are being used for vaccine development, were characterized. Three isolates were…”
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Restriction fragment length polymorphism analysis for rapid gag subtype determination of human immunodeficiency virus Type 1 in South Africa
Published in Journal of virological methods (01-03-1999)“…A rapid method for identification of human immunodeficiency virus Type 1 (HIV-1) gag subtypes was developed based on restriction fragment length polymorphism…”
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At the forefront of protecting indigenous knowledge
Published in Managing Intellectual Property (01-05-2008)“…At the ninth session of the Intergovernmental Committee on Intellectual Property and Genetic Resources, Traditional Knowledge and Folklore at WIPO in Geneva,…”
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