Search Results - "van Ham, J J"
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Challenges in reduction of dinitrogen by proton and electron transfer
Published in Chemical Society reviews (07-08-2014)“…Ammonia is an important nutrient for the growth of plants. In industry, ammonia is produced by the energy expensive Haber-Bosch process where dihydrogen and…”
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Finished genome of the fungal wheat pathogen Mycosphaerella graminicola reveals dispensome structure, chromosome plasticity, and stealth pathogenesis
Published in PLoS genetics (01-06-2011)“…The plant-pathogenic fungus Mycosphaerella graminicola (asexual stage: Septoria tritici) causes septoria tritici blotch, a disease that greatly reduces the…”
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Impact of (chemo)radiotherapy on immune cell composition and function in cervical cancer patients
Published in Oncoimmunology (01-02-2017)“…New treatments based on combinations of standard therapeutic modalities and immunotherapy are of potential use, but require a profound understanding of immune…”
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The genomes of the fungal plant pathogens Cladosporium fulvum and Dothistroma septosporum reveal adaptation to different hosts and lifestyles but also signatures of common ancestry
Published in PLoS genetics (01-11-2012)“…We sequenced and compared the genomes of the Dothideomycete fungal plant pathogens Cladosporium fulvum (Cfu) (syn. Passalora fulva) and Dothistroma septosporum…”
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Tumor‐infiltrating CD14‐positive myeloid cells and CD8‐positive T‐cells prolong survival in patients with cervical carcinoma
Published in International journal of cancer (15-12-2013)“…One of the hallmarks of cancer is the influx of myeloid cells. In our study, we investigated the constitution of tumor‐infiltrating myeloid cells and their…”
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Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages in zebrafish spinal cord regeneration
Published in Nature communications (07-11-2018)“…Spinal cord injury leads to a massive response of innate immune cells in non-regenerating mammals, but also in successfully regenerating zebrafish. However,…”
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Apoptotic Cells Are Cleared by Directional Migration and elmo1- Dependent Macrophage Engulfment
Published in Current biology (08-05-2012)“…Apoptotic cell death is essential for development and tissue homeostasis [1, 2]. Failure to clear apoptotic cells can ultimately cause inflammation and…”
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Zebrafish macrophage developmental arrest underlies depletion of microglia and reveals Csf1r-independent metaphocytes
Published in eLife (05-05-2020)“…Macrophages derive from multiple sources of hematopoietic progenitors. Most macrophages require colony-stimulating factor 1 receptor (CSF1R), but some…”
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A Small Molecule that Induces Intrinsic Pathway Apoptosis with Unparalleled Speed
Published in Cell reports (Cambridge) (01-12-2015)“…Apoptosis is generally believed to be a process that requires several hours, in contrast to non-programmed forms of cell death that can occur in minutes. Our…”
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The blood mMDSC to DC ratio is a sensitive and easy to assess independent predictive factor for epithelial ovarian cancer survival
Published in Oncoimmunology (01-01-2018)“…Epithelial ovarian cancer (EOC) may cause abnormal blood levels of leukocytes. This paraneoplastic manifestation is associated with a worse response to therapy…”
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Homozygous Mutations in CSF1R Cause a Pediatric-Onset Leukoencephalopathy and Can Result in Congenital Absence of Microglia
Published in American journal of human genetics (02-05-2019)“…Microglia are CNS-resident macrophages that scavenge debris and regulate immune responses. Proliferation and development of macrophages, including microglia,…”
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Tbet-positive regulatory T cells accumulate in oropharyngeal cancers with ongoing tumor-specific type 1 T cell responses
Published in Journal for immunotherapy of cancer (18-01-2019)“…Regulatory T cells (Tregs) may comprise different subsets allowing them to efficiently suppress different types of effector T cells. In this study, we show…”
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A quantitative and dynamic model of the Arabidopsis flowering time gene regulatory network
Published in PloS one (26-02-2015)“…Various environmental signals integrate into a network of floral regulatory genes leading to the final decision on when to flower. Although a wealth of…”
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Frames of reference and categorical/coordinate spatial relations in a “what was where” task
Published in Experimental brain research (01-09-2016)“…The aim of this study was to explore how people use egocentric (i.e., with respect to their body) and allocentric (i.e., with respect to another element in the…”
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Bayesian Markov Random Field analysis for protein function prediction based on network data
Published in PloS one (24-02-2010)“…Inference of protein functions is one of the most important aims of modern biology. To fully exploit the large volumes of genomic data typically produced in…”
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Nitric oxide density distributions in the effluent of an RF argon APPJ: effect of gas flow rate and substrate
Published in New journal of physics (02-12-2014)“…The effluent of an RF argon atmospheric pressure plasma jet, the so-called kinpen, is investigated with focus on the nitric-oxide (NO) distribution for laminar…”
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Gene expression profiling reveals a conserved microglia signature in larval zebrafish
Published in Glia (01-02-2020)“…Microglia are the resident macrophages of the brain. Over the past decade, our understanding of the function of these cells has significantly improved…”
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Reductive Genome Evolution in Buchnera aphidicola
Published in Proceedings of the National Academy of Sciences - PNAS (21-01-2003)“…We have sequenced the genome of the intracellular symbiont Buchnera aphidicola from the aphid Baizongia pistacea. This strain diverged 80-150 million years ago…”
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Dectin-1/2-induced autocrine PGE2 signaling licenses dendritic cells to prime Th2 responses
Published in PLoS biology (01-04-2018)“…The molecular mechanisms through which dendritic cells (DCs) prime T helper 2 (Th2) responses, including those elicited by parasitic helminths, remain…”
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How does the corpus callosum mediate interhemispheric transfer? A review
Published in Behavioural brain research (30-09-2011)“…► Corpus callosum important structure in brain hemisphere communication. ► Two theories regarding callosal function; inhibition and excitation. ► Evidence for…”
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