Search Results - "van Hagen, T."

Assessing spatial pattern separation in rodents using the object pattern separation task by van Goethem, Nick P., van Hagen, Britt T. J., Prickaerts, Jos

“…Pattern separation is the process of transforming highly similar sensory inputs into distinct, dissimilar representations. It takes place in the hippocampus…”
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Prognostic value of systemic inflammation-based markers in advanced pancreatic cancer by Martin, H. L., Ohara, K., Kiberu, A., Van Hagen, T., Davidson, A., Khattak, M. A.

“…Background The prognostic significance of various systemic inflammation‐based markers has been explored in different cancers. These markers can be used to…”
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Publisher Correction: Assessing spatial pattern separation in rodents using the object pattern separation task by van Goethem, Nick P., van Hagen, Britt T. J., Prickaerts, Jos

“…In the HTML version of this paper originally published online, text in Table 6 was misaligned in a way that made it difficult to determine which entries in the…”
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Pharmacological depletion of microglia and perivascular macrophages prevents vascular Cognitive Impairment in Ang II-induced Hypertension by Kerkhofs, Danielle, van Hagen, Britt T., Milanova, Irina V., Schell, Kimberly J., van Essen, Helma, Wijnands, Erwin, Goossens, Pieter, Blankesteijn, W. Matthijs, Unger, Thomas, Prickaerts, Jos, Biessen, Erik A., van Oostenbrugge, Robert J., Foulquier, Sébastien

“…Rationale: Hypertension is a major risk factor for cerebral small vessel disease, the most prevalent cause of vascular cognitive impairment. As we have shown,…”
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Hypertension-induced cognitive impairment: insights from prolonged angiotensin II infusion in mice by Foulquier, Sébastien, Namsolleck, Pawel, Van Hagen, Britt T., Milanova, Irina, Post, Mark J., Blankesteijn, W. Matthijs, Rutten, Bart P., Prickaerts, Jos, Van Oostenbrugge, Robert J., Unger, Thomas

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Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer’s disease by Ricciarelli, Roberta, Brullo, Chiara, Prickaerts, Jos, Arancio, Ottavio, Villa, Carla, Rebosio, Claudia, Calcagno, Elisa, Balbi, Matilde, van Hagen, Britt T. J., Argyrousi, Elentina K., Zhang, Hong, Pronzato, Maria Adelaide, Bruno, Olga, Fedele, Ernesto

“…Memory loss characterizes several neurodegenerative disorders, including Alzheimer’s disease (AD). Inhibition of type 4 phosphodiesterase (PDE4) and elevation…”
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Pro-cognitive effect of upregulating cyclic guanosine monophosphate signalling during memory acquisition or early consolidation is mediated by increased AMPA receptor trafficking by Argyrousi, Elentina K, Heckman, Pim RA, van Hagen, Britt TJ, Muysers, Hannah, van Goethem, Nick P, Prickaerts, Jos

“…Background: Episodic memory consists of different mnemonic phases, including acquisition and early and late consolidation. Each of these phases is…”
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Design of a Rotating Facility for Extracorporal Treatment of an Explanted Liver with Disseminated Metastases by Boron Neutron Capture Therapy with an Epithermal Neutron Beam by Nievaart, V. A., Moss, R. L., Kloosterman, J. L., van der Hagen, T. H J. J., van Dam, H., Wittig, A., Malago, M., Sauerwein, W.

“…Nievaart, V. A., Moss, R. L., Kloosterman, J. L., van der Hagen, T. H. J. J., van Dam, H., Wittig, A., Malago, M. and Sauerwein, W. Design of a Rotating…”
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Experimental investigations on flashing-induced instabilities in one and two-parallel channels: A comparative study by Marcel, Christian P., Rohde, M., Van Der Hagen, T.H.J.J.

“…In this investigation, experiments conducted in a natural circulation test facility at low power and low pressure conditions, in the one single and…”
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Reactivity control system of a passively safe thorium breeder pebble bed reactor by Wols, F.J., Kloosterman, J.L., Lathouwers, D., van der Hagen, T.H.J.J.

“…•A worth of over 15,000pcm ensures achieving long-term cold shutdown in thorium PBR.•Control rod worth in side reflector is insufficient due to low-power…”
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Downscaling a supercritical water loop for experimental studies on system stability by Rohde, M., Marcel, C.P., T’Joen, C., Class, A.G., van der Hagen, T.H.J.J.

“…In industry, supercritical water is being used as e.g. separation agent, solvent or coolant due to the unique fluid properties near the critical point. This…”
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Experimental and numerical investigations on flashing-induced instabilities in a single channel by Marcel, Christian P., Rohde, M., Van Der Hagen, T.H.J.J.

“…During the start-up phase, natural circulation BWRs (NC-BWRs) need to be operated at low pressure conditions. Such conditions favor flashing-induced…”
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Fluid-to-fluid modeling of supercritical water loops for stability analysis by Marcel, C.P., Rohde, M., Masson, V.P., Van der Hagen, T.H.J.J.

“…The use of supercritical water as coolant/moderator may induce oscillations in the supercritical light water reactor similar to the density wave oscillations…”
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Three-dimensional flow pattern visualization and bubble size distributions in stationary and transient upward flashing flow by Manera, A., Prasser, H.-M., Lucas, D., van der Hagen, T.H.J.J.

“…For the first time, an experimental three-dimensional reconstruction and visualization of stationary and transient flashing flow in a vertical pipe (47 mm…”
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Application of adjoint Monte Carlo to accelerate simulations of mono-directional beams in treatment planning for Boron Neutron Capture Therapy by Nievaart, V. A., Légràdy, D., Moss, R. L., Kloosterman, J. L., van der Hagen, T. H. J. J., van Dam, H.

“…This paper deals with the application of the adjoint transport theory in order to optimize Monte Carlo based radiotherapy treatment planning. The technique is…”
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Investigating the ESBWR stability with experimental and numerical tools: A comparative study by Rohde, M., Marcel, C.P., Manera, A., Van der Hagen, T.H.J.J., Shiralkar, B.

“…In this work, the stability of the Economic Simplified Boiling Water Reactor (ESBWR) has been studied by using a Freon-134a based experimental facility…”
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Biased 5-HT1A receptor agonists F13714 and NLX-101 differentially affect pattern separation and neuronal plasticity in rats after acute and chronic treatment by van Hagen, Britt T.J., van Goethem, Nick P., Nelissen, Ellis, Paes, Dean, Koymans, Karin, van Hoof, Scott, Schreiber, Rudy, Varney, Mark, Newman-Tancredi, Adrian, Prickaerts, Jos

“…Pattern separation is a hippocampal process in which highly similar stimuli are recognized as separate representations, and deficits could lead to memory…”
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Fluid-to-fluid modeling of natural circulation boiling loops for stability analysis by Marcel, C.P., Rohde, M., Van der Hagen, T.H.J.J.

“…Gravity driven flows may induce oscillations influencing the stability of natural circulation nuclear boiling water reactors. To experimentally study such…”
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Soluble guanylate cyclase stimulator riociguat improves spatial memory in mice via peripheral mechanisms by Nelissen, Ellis, van Hagen, Britt T.J., Argyrousi, Elentina K., van Goethem, Nick P., Heckman, Pim R.A., Paes, Dean, Mulder-Jongen, Danielle A.J., Ramaekers, Johannes G., Blokland, Arjan, Schmidt, Harald H.H.W., Prickaerts, Jos

“…•Subtle stimulation of sGC by riociguat is sufficient to enhance memory.•Vascular mechanisms may contribute to the memory enhancing effects of…”
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Hypertension-induced cognitive impairment: insights from prolonged angiotensin II infusion in mice by Foulquier, Sébastien, Namsolleck, Pawel, Van Hagen, Britt T, Milanova, Irina, Post, Mark J, Blankesteijn, W Matthijs, Rutten, Bart P, Prickaerts, Jos, Van Oostenbrugge, Robert J, Unger, Thomas

“…The causal relation between hypertension and cerebral small vessel disease (cSVD) remains elusive, and appropriate animal models are scarce. We aimed to assess…”
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