Search Results - "van Hagen, P. M."

The complement system in glioblastoma multiforme by Bouwens van der Vlis, T A M, Kros, J M, Mustafa, D A M, van Wijck, R T A, Ackermans, L, van Hagen, P M, van der Spek, P J

“…The human complement system is represents the main effector arm of innate immunity and its ambivalent function in cancer has been subject of ongoing dispute…”
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Orbit-Infiltrating Mast Cells, Monocytes, and Macrophages Produce PDGF Isoforms that Orchestrate Orbital Fibroblast Activation in Graves' Ophthalmopathy by van Steensel, L, Paridaens, D, van Meurs, M, van Hagen, P. M, van den Bosch, W. A, Kuijpers, R. W. A. M, Drexhage, H. A, Hooijkaas, H, Dik, W. A

“…Purpose: Platelet-derived growth factors (PDGF) are regulators of fibroblast activity that may be involved in the pathophysiology of Graves' ophthalmopathy…”
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The effect of etanercept on Graves' ophthalmopathy: a pilot study by PARIDAENS, D, VAN DEN BOSCH, W. A, VAN DER LOOS, T. L, KRENNING, E. P, VAN HAGEN, P. M

“…To assess the effect of etanercept, an antitumour necrosis factor (anti-TNF) drug, on clinical signs in Graves' ophthalmopathy (GO). A total of 10 consecutive…”
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Adult orbital xanthogranuloma: long-term follow-up of treated cases by Detiger, S. E., Hötte, G. J., Verdijk, R. M., de Keizer, R. O. B., van Hagen, P. M., van Laar, J. A. M., Paridaens, D.

“…Background Adult orbital xanthogranulomatous disease (AOXGD) is a group of rare disorders. Four subtypes are identified: adult-onset xanthogranuloma (AOX),…”
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Autologous peripheral retinal pigment epithelium translocation in patients with subfoveal neovascular membranes by van Meurs, J C, ter Averst, E, Hofland, L J, van Hagen, P M, Mooy, C M, Baarsma, G S, Kuijpers, R W, Boks, T, Stalmans, P

“…Aim: To evaluate the possibility of translocating autologous peripheral retinal pigment epithelial (RPE) cells and enhance their adhesion to improve functional…”
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Tuberculosis and other causes of uveitis in Indonesia by La Distia Nora, R, Sitompul, R, Bakker, M, Susiyanti, M, Edwar, L, Sjamsoe, S, Singh, G, van Hagen, M P, Rothova, A

“…Purpose The purpose of this study is to assess the causes of uveitis in Indonesia and determine the importance of tuberculosis (TB) as a cause of uveitis…”
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Soluble Interleukin-2 Receptor: A Potential Marker for Monitoring Disease Activity in IgG4-Related Disease by van Laar, J. A. M., van Hagen, P. M., Bansie, R. D., Eurelings, L. E. M., Karim, A. F., Dik, Wim A.

“…Background. IgG4-related disease (IgG4-RD) is a fibroinflammatory condition. T-cells play a crucial role in the pathogenesis, and therefore, serum soluble…”
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Needs, Perceptions and Education in Sarcoidosis: A Live Interactive Survey of Patients and Partners by Moor, C. C., van Manen, M. J. G., van Hagen, P. M., Miedema, J. R., van den Toorn, L. M., Gür-Demirel, Y., Berendse, A. P. C., van Laar, J. A. M., Wijsenbeek, M. S.

“…Objectives Sarcoidosis is a chronic, multisystem disease with often a major impact on quality of life. Information on unmet needs of patients and their…”
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Atopic Manifestations Are Underestimated Clinical Features in Various Primary Immunodeficiency Disease Phenotypes by de Wit, J, Dalm, V Ash, Totté, J Ee, Kamphuis, L Sj, Vermont, C L, van Osnabrugge, F Y, van Hagen, P M, Pasmans, S Gma

“…Atopic manifestations are described as a clinical feature of various primary immunodeficiency disease (PID) phenotypes and are frequently reported in combined…”
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Infliximab for IgG4-Related Orbital Disease by Karim, Faiz, Paridaens, D, Westenberg, L E H, Guenoun, J, Verdijk, R M, van Hagen, P M, van Laar, J A M

“…IgG4-related disease (IgG4-RD) is a systemic fibroinflammatory condition with unclear pathophysiology. It may occur as a single organ disorder, but multiorgan…”
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The treatment outcomes in IgG4-related disease by Karim, A F, Bansie, R D, Rombach, S M, Paridaens, D, Verdijk, R M, van Hagen, P M, Van Laar, J A M

“…IgG4-related disease (IgG4-RD) is an emerging systemic inflammatory disease involving nearly all organs eventually leading to fibrosis. Prompt and adequate…”
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PDGF Enhances Orbital Fibroblast Responses to TSHR Stimulating Autoantibodies in Graves' Ophthalmopathy Patients by van Steensel, L, Hooijkaas, H, Paridaens, D, van den Bosch, W. A, Kuijpers, R. W. A. M, Drexhage, H. A, van Hagen, P. M, Dik, W. A

“…Purpose: Thyroid-stimulating hormone receptor (TSHR) stimulating autoantibodies are associated with Graves' ophthalmopathy (GO), the orbital manifestation of…”
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Anti-TNF-α therapy for sight threatening uveitis by Lindstedt, E W, Baarsma, G S, Kuijpers, R W A M, van Hagen, P M

“…Aim: To describe the effect of additional treatment with anti-TNF-α therapy in a case series of 13 patients with serious sight threatening uveitis. Methods: 13…”
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Behçet's disease, hospital-based prevalence and manifestations in the Rotterdam area by Kappen, J H, van Dijk, E H C, Baak-Dijkstra, M, van Daele, P L A, Lam-Tse, W K, van Hagen, P M, van Laar, J A M

“…Behçet's disease is most prevalent in countries along the former Silk Road. Prevalence varies from 70-420 per 100,000 in Turkey, and 13.5-20 and 1-2 per…”
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Are Patients at Risk for Recurrent Disease Activity After Switching From Remicade® to Remsima®? An Observational Study by Xue, Laixi, van Bilsen, K., Schreurs, M. W. J., van Velthoven, M. E. J., Missotten, T. O., Thiadens, A. A. H. J., Kuijpers, R. W. A. M., van Biezen, P., Dalm, V. A. S. H., van Laar, J. A. M., Hermans, M. A. W., Dik, W. A., van Daele, P. L. A., van Hagen, P. M.

“…Background: Since the late ‘90s, infliximab (Remicade ® ) is being used successfully to treat patients with several non-infectious immune mediated inflammatory…”
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Patients treated with high‐dose intravenous immunoglobulin show selective activation of regulatory T cells by Tjon, A. S. W., Tha‐In, T., Metselaar, H. J., Gent, R., Laan, L. J. W., Groothuismink, Z. M. A., Boekhorst, P. A. W., Hagen, P. M., Kwekkeboom, J.

“…Summary Intravenous immunoglobulin (IVIg) is used to treat autoimmune and systemic inflammatory diseases caused by derailment of humoral and cellular immunity…”
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The peripheral blood compartment in patients with Graves' disease: activated T lymphocytes and increased transitional and pre‐naive mature B lymphocytes by Van der Weerd, K., Van Hagen, P. M., Schrijver, B., Kwekkeboom, D. J., De Herder, W. W., Ten Broek, M. R. J., Postema, P. T. E., Van Dongen, J. J. M., Staal, F. J. T., Dik, W. A.

“…Summary Graves' disease (GD) is an autoimmune disease that involves aberrant B and T lymphocyte responses. Detailed knowledge about lymphocyte subpopulation…”
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Somatostatin and the immune and haematopoetic system; a review by van Hagen, P M, Krenning, E P, Kwekkeboom, D J, Reubi, J C, Anker-Lugtenburg, P J, Löwenberg, B, Lamberts, S W

“…SS-R and SS have been demonstrated in non-pathological and pathological lymphoid tissue and may play a regulatory, mostly inhibitory, role in the immune…”
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Evaluation of a radiolabelled cyclic DTPA‐RGD analogue for tumour imaging and radionuclide therapy by van Hagen, P.M., Breeman, W.A.P., Bernard, H.F., Schaar, M., Mooij, C.M., Srinivasan, A., Schmidt, M.A., Krenning, E.P., de Jong, M.

“…Tumours depend on sufficient blood supply for their growth. They are able to promote new blood vessel formation (neoangiogenesis) via angiogenic factors…”
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Immunopathogenesis of Behçet's disease and treatment modalities by van der Houwen, T.B., van Hagen, P.M., van Laar, J.A.M.

“…Behçet's disease (BD) is an auto-inflammatory disease, primarily characterized by recurrent painful mucocutaneous ulcerations. A literature search was…”
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