Search Results - "van Haaften, Wouter T"
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Peribiliary Glands Are Key in Regeneration of the Human Biliary Epithelium After Severe Bile Duct Injury
Published in Hepatology (Baltimore, Md.) (01-04-2019)“…Peribiliary glands (PBG) are a source of stem/progenitor cells organized in a cellular network encircling large bile ducts. Severe cholangiopathy with loss of…”
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Intestinal Activation of pH-Sensing Receptor OGR1 [GPR68] Contributes to Fibrogenesis
Published in Journal of Crohn's and colitis (15-11-2018)“…pH-sensing ovarian cancer G-protein coupled receptor-1 [OGR1/GPR68] is regulated by key inflammatory cytokines. Patients suffering from inflammatory bowel…”
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Serological Biomarkers of Tissue Turnover Identify Responders to Anti-TNF Therapy in Crohn's Disease: A Pilot Study
Published in Clinical and translational gastroenterology (01-09-2020)“…Anti-tumor necrosis factor (TNF) therapy is effective in inducing remission in Crohn's disease in 60% of patients. No serological biomarkers are available,…”
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Histopathologic and molecular evaluation of the Organ Procurement and Transplantation Network selection criteria for intestinal graft donation
Published in The Journal of surgical research (01-06-2014)“…Abstract Background The Organ Procurement and Transplantation Network (OPTN) has formulated criteria for the selection of donors for intestinal…”
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Long noncoding RNA H19X is a key mediator of TGF-β-driven fibrosis
Published in The Journal of clinical investigation (01-09-2020)“…TGF-β is a master regulator of fibrosis, driving the differentiation of fibroblasts into apoptosis-resistant myofibroblasts and sustaining the production of…”
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The Citrullinated and MMP-degraded Vimentin Biomarker (VICM) Predicts Early Response to Anti-TNFα Treatment in Crohn’s Disease
Published in Journal of clinical gastroenterology (01-01-2021)“…BACKGROUND:In Crohn’s disease (CD), 10% to 40% of patients do not respond to anti-tumor necrosis factor-α (TNFα) treatment. Currently, there are no biomarkers…”
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Serological Biomarkers of Tissue Turnover Can Early Identify Responders to Infliximab in Crohn's Disease
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2017)Get full text
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189 MMP Degraded Type III Collagen Is a Novel Serological Biomarker for Penetrating (Montreal B3) Crohn's Disease
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2016)Get full text
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Tu1238 Fibrotic Human Precision-Cut Intestinal Slices: A New Ex Vivo Model for Established Intestinal Fibrosis
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2014)Get full text
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Sa1887 - Serological Biomarkers of Tissue Turnover Can Early Identify Responders to Infliximab in Crohn's Disease
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2017)Get full text
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Long noncoding RNA H19X is a key mediator of TGF-[beta]-driven fibrosis
Published in The Journal of clinical investigation (01-09-2020)“…TGF-[beta] is a master regulator of fibrosis, driving the differentiation of fibroblasts into apoptosis-resistant myofibroblasts and sustaining the production…”
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