Search Results - "van Groningen, Tomas"

Comparative physiology and efficacy of atropine and scopolamine in sarin nerve agent poisoning by Cornelissen, Alex S., Klaassen, Steven D., van Groningen, Tomas, Bohnert, Sara, Joosen, Marloes J.A.

“…Anticholinergic treatment is key for effective medical treatment of nerve agent exposure. Atropine is included at a 2 mg intramuscular dose in so-called…”
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Elucidation of in Vitro Chlorinated Tyrosine Adducts in Blood Plasma as Selective Biomarkers of Chlorine Exposure by de Bruin-Hoegée, Mirjam, van Damme, Irene M., van Groningen, Tomas, van der Riet-van Oeveren, Debora, Noort, Daan, van Asten, Arian C.

“…Chlorine is a widely available industrial chemical and involved in a substantial number of cases of poisoning. It has also been used as a chemical warfare…”
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Pharmacokinetics and efficacy of atropine sulfate/obidoxime chloride co-formulation against VX in a guinea pig model by Kentrop, Jiska, Savransky, Vladimir, Klaassen, Steven D., van Groningen, Tomas, Bohnert, Sara, Cornelissen, Alex S., Cochrane, Laura, Barry, John, Joosen, Marloes J.A.

“…Nerve agent exposure is generally treated by an antidote formulation composed of a muscarinic antagonist, atropine sulfate (ATR), and a reactivator of…”
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On-site detection and laboratory verification of the presence of nerve agent biomarkers using dried blood spots by de Bruin-Hoegée, Mirjam, Fidder, Alex, van Groningen, Tomas, van der Schans, Marcel J., Noort, Daan, van Asten, Arian C.

“…[Display omitted] •Stable nerve agent biomarkers were identified in dried blood spots.•The cholinesterase activity was measured by a mobile test kit months…”
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Efficacy of atropine sulfate/obidoxime chloride co-formulation against sarin exposure in guinea pigs by Joosen, Marloes J.A., Klaassen, Steven D., Verheij, Elwin, van Groningen, Tomas, Cornelissen, Alex S., Skiadopoulos, Mario H., Cochrane, Laura, Shearer, Jeff D.

“…The efficacy and pharmacokinetics of the aqueous co-formulation contents of the Trobigard™ (atropine sulfate, obidoxime chloride) auto-injector were evaluated…”
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