Search Results - "van Grieken, Nicole C.T"
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Risk and Epidemiological Time Trends of Gastric Cancer in Lynch Syndrome Carriers in The Netherlands
Published in Gastroenterology (New York, N.Y. 1943) (01-02-2010)“…Background & Aims Although gastric cancer forms part of the Lynch syndrome tumor spectrum, the risk of developing gastric cancer in Lynch syndrome families is…”
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Gastric Cancer Risk in Patients With Premalignant Gastric Lesions: A Nationwide Cohort Study in the Netherlands
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2008)“…Background & Aims: A cascade of precursor lesions (eg, atrophic gastritis, intestinal metaplasia, and dysplasia) precedes most gastric adenocarcinomas…”
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The staging of gastritis with the OLGA system by using intestinal metaplasia as an accurate alternative for atrophic gastritis
Published in Gastrointestinal endoscopy (01-06-2010)“…Background The OLGA (operative link on gastritis assessment) staging system is based on severity of atrophic gastritis (AG). AG remains a difficult…”
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IBD-Associated Dysplastic Lesions Show More Chromosomal Instability Than Sporadic Adenomas
Published in Inflammatory bowel diseases (06-01-2020)“…Inflammatory bowel disease (IBD) patients are at increased risk of developing colorectal cancer. However, histologically, it is challenging to distinguish…”
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Karyotype evolution in response to chemoradiotherapy and upon recurrence of esophageal adenocarcinomas
Published in Cell reports (Cambridge) (01-11-2024)“…The genome of esophageal adenocarcinoma (EAC) is highly unstable and might evolve over time. Here, we track karyotype evolution in EACs in response to…”
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Why is colon cancer survival improving by time? A nationwide survival analysis spanning 35 years
Published in International journal of cancer (01-08-2017)“…There is limited information present to explain temporal improvements in colon cancer survival. This nationwide study investigates the temporal changes in…”
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Prognostic value of tumor markers and ctDNA in patients with resectable gastric cancer receiving perioperative treatment: results from the CRITICS trial
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01-03-2022)“…Aim To evaluate the prognostic value of tumor markers in a European cohort of patients with resectable gastric cancer. Methods We performed a post hoc analysis…”
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Phosphotyrosine-based-phosphoproteomics scaled-down to biopsy level for analysis of individual tumor biology and treatment selection
Published in Journal of proteomics (06-06-2017)“…Mass spectrometry-based phosphoproteomics of cancer cell and tissue lysates provides insight in aberrantly activated signaling pathways and potential drug…”
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Longitudinal immune monitoring of patients with resectable esophageal adenocarcinoma treated with Neoadjuvant PD-L1 checkpoint inhibition
Published in Oncoimmunology (31-12-2023)“…The analysis of peripheral blood mononuclear cells (PBMCs) by flow cytometry holds promise as a platform for immune checkpoint inhibition (ICI) biomarker…”
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Microdissected pancreatic cancer proteomes reveal tumor heterogeneity and therapeutic targets
Published in JCI insight (06-08-2020)“…Pancreatic ductal adenocarcinoma (PDAC) is characterized by a relative paucity of cancer cells that are surrounded by an abundance of nontumor cells and…”
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Circulating Tumor DNA Analysis: Clinical Implications for Colorectal Cancer Patients. A Systematic Review
Published in JNCI cancer spectrum (01-09-2019)“…Liquid biopsies could improve diagnosis, prognostication, and monitoring of colorectal cancer (CRC). Mutation, chromosomal copy number alteration, and…”
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Biopsy Strategies for Endoscopic Surveillance of Pre-malignant Gastric Lesions
Published in Helicobacter (Cambridge, Mass.) (01-08-2010)“…Background: Endoscopic surveillance of pre‐malignant gastric lesions may add to gastric cancer prevention. However, the appropriate biopsy regimen for optimal…”
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Chromosome 5q Loss in Colorectal Flat Adenomas
Published in Clinical cancer research (01-09-2012)“…Flat adenomas are a subgroup of colorectal adenomas that have been associated with a more aggressive clinical behavior compared with their polypoid…”
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Duodenal lymphoid nodularity in common variable immunodeficiency
Published in Digestive and liver disease (01-02-2013)Get full text
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Genome-wide cell-free DNA fragmentation in patients with cancer
Published in Nature (London) (01-06-2019)“…Cell-free DNA in the blood provides a non-invasive diagnostic avenue for patients with cancer 1 . However, characteristics of the origins and molecular…”
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Distinct chromosomal aberrations in Epstein-Barr virus–carrying gastric carcinomas tested by comparative genomic hybridization
Published in Gastroenterology (New York, N.Y. 1943) (01-09-2001)“…Background & Aims: Approximately 10% of gastric adenocarcinomas carry the human pathogenic Epstein-Barr virus (EBV). The role of EBV in the pathogenesis of…”
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Neoadjuvant Chemoradiotherapy Combined with Atezolizumab for Resectable Esophageal Adenocarcinoma: A Single-arm Phase II Feasibility Trial (PERFECT)
Published in Clinical cancer research (15-06-2021)“…The CROSS trial established neoadjuvant chemoradiotherapy (nCRT) for patients with resectable esophageal adenocarcinoma (rEAC). In the PERFECT trial, we…”
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Hereditary diffuse gastric cancer: updated clinical guidelines with an emphasis on germline CDH1 mutation carriers
Published in Journal of medical genetics (01-06-2015)“…Germline CDH1 mutations confer a high lifetime risk of developing diffuse gastric (DGC) and lobular breast cancer (LBC). A multidisciplinary workshop was…”
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Sialic acids in pancreatic cancer cells drive tumour-associated macrophage differentiation via the Siglec receptors Siglec-7 and Siglec-9
Published in Nature communications (24-02-2021)“…Changes in glycosylation during tumour progression are a key hallmark of cancer. One of the glycan moieties generally overexpressed in cancer are sialic acids,…”
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Quantitative assessment of gastric corpus atrophy in subjects using omeprazole: a randomized follow-up study
Published in The American journal of gastroenterology (01-10-2001)“…OBJECTIVES: Atrophy of the gastric mucosa most frequently results from chronic Helicobacter pylori infection and is a risk factor for the development of…”
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