Search Results - "van Grieken, N C T"

KRAS and BRAF mutations are rare and related to DNA mismatch repair deficiency in gastric cancer from the East and the West: Results from a large international multicentre study by van Grieken, N C T, Aoyma, T, Chambers, P A, Bottomley, D, Ward, L C, Inam, I, Buffart, T E, Das, K, Lim, T, Pang, B, Zhang, S L, Tan, I B, Carvalho, B, Heideman, D A M, Miyagi, Y, Kameda, Y, Arai, T, Meijer, G A, Tsuburaya, A, Tan, P, Yoshikawa, T, Grabsch, H I

“…Background: Inhibitors of the epidermal growth factor (EGFR) signaling pathway have a major role in the treatment of KRAS wild-type colorectal cancer patients…”
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Effect of preoperative chemotherapy on the histopathological classification of gastric cancer by Caspers, I. A., Biesma, H. D., Wiklund, K., Pontén, F., Lind, P., Nordsmark, M., Sikorska, K., Meershoek-KleinKranenbarg, E., Hartgrink, H. H., van de Velde, C. J. H., van Sandick, J. W., Verheij, M., Cats, A., van Grieken, N. C. T.

“…Background In the era of individualized gastric cancer (GC) treatment, accurate determination of histological subtype becomes increasingly relevant. As yet, it…”
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Discordance in HER2 Status in Gastro-esophageal Adenocarcinomas: A Systematic Review and Meta-analysis by Creemers, A., ter Veer, E., de Waal, L., Lodder, P., Hooijer, G. K. J., van Grieken, N. C. T., Bijlsma, M. F., Meijer, S. L., van Oijen, M. G. H., van Laarhoven, H. W. M.

“…Trastuzumab combined with chemotherapy is standard of care for HER2 positive advanced gastro-esophageal cancers. The reported prevalence of HER2 discordance…”
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Impact of upfront randomization for postoperative treatment on quality of surgery in the CRITICS gastric cancer trial by Claassen, Y. H. M., Hartgrink, H. H., de Steur, W. O., Dikken, J. L., van Sandick, J. W., van Grieken, N. C. T., Cats, A., Trip, A. K., Jansen, E. P. M., Kranenbarg, W. M. Meershoek-Klein, Braak, J. P. B. M., Putter, H., van Berge Henegouwen, M. I., Verheij, M., van de Velde, C. J. H.

“…Background Preoperative randomization for postoperative treatment might affect quality of surgery. In the CRITICS trial (ChemoRadiotherapy after Induction…”
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MAL promoter hypermethylation as a novel prognostic marker in gastric cancer by Buffart, T E, Overmeer, R M, Steenbergen, R D M, Tijssen, M, van Grieken, N C T, Snijders, P J F, Grabsch, H I, van de Velde, C J H, Carvalho, B, Meijer, G A

“…T-lymphocyte maturation associated protein, MAL, has been described as a tumour-suppressor gene with diagnostic value in colorectal and oesophageal cancers,…”
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Association between hospital volume and quality of gastric cancer surgery in the CRITICS trial by Claassen, Y. H. M., van Sandick, J. W., Hartgrink, H. H., Dikken, J. L., De Steur, W. O., van Grieken, N. C. T., Boot, H., Cats, A., Trip, A. K., Jansen, E. P. M., Meershoek‐Klein Kranenbarg, W. M., Braak, J. P. B. M., Putter, H., van Berge Henegouwen, M. I., Verheij, M., van de Velde, C. J. H.

“…Background Studies investigating the association between hospital volume and quality of gastric cancer surgery are lacking. In the present study, the effect of…”
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[89Zr]Zr-cetuximab PET/CT as biomarker for cetuximab monotherapy in patients with RAS wild-type advanced colorectal cancer by van Helden, E. J., Elias, S. G., Gerritse, S. L., van Es, S. C., Boon, E., Huisman, M. C., van Grieken, N. C. T., Dekker, H., van Dongen, G. A. M. S., Vugts, D. J., Boellaard, R., van Herpen, C. M. L., de Vries, E. G. E., Oyen, W. J. G., Brouwers, A. H., Verheul, H. M. W., Hoekstra, O. S., Menke-van der Houven van Oordt, C. W.

“…Purpose One-third of patients with RAS wild-type mCRC do not benefit from anti-EGFR monoclonal antibodies. This might be a result of variable pharmacokinetics…”
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Renal cancer and pneumothorax risk in Birt–Hogg–Dubé syndrome; an analysis of 115 FLCN mutation carriers from 35 BHD families by Houweling, A C, Gijezen, L M, Jonker, M A, van Doorn, M B A, Oldenburg, R A, van Spaendonck-Zwarts, K Y, Leter, E M, van Os, T A, van Grieken, N C T, Jaspars, E H, de Jong, M M, Bongers, E M H F, Johannesma, P C, Postmus, P E, van Moorselaar, R J A, van Waesberghe, J-Htm, Starink, T M, van Steensel, M A M, Gille, J J P, Menko, F H

“…Background: Birt–Hogg–Dubé (BHD) syndrome is an autosomal dominant condition caused by germline FLCN mutations, and characterised by fibrofolliculomas,…”
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Prognostic value of BRAF and KRAS mutation status in stage II and III microsatellite instable colon cancers by de Cuba, E.M.V., Snaebjornsson, P., Heideman, D.A.M., van Grieken, N.C.T., Bosch, L.J.W., Fijneman, R.J.A., Belt, E., Bril, H., Stockmann, H.B.A.C., Hooijberg, E., Punt, C.J.A., Koopman, M., Nagtegaal, I.D., Coupé, V.H.M., Carvalho, B., Meijer, G.A.

“…Microsatellite instability (MSI) has been associated with favourable survival in early stage colorectal cancer (CRC) compared to microsatellite stable (MSS)…”
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Correction to: [89Zr]Zr-cetuximab PET/CT as biomarker for cetuximab monotherapy in patients with RAS wild-type advanced colorectal cancer by van Helden, E. J., Elias, S. G., Gerritse, S. L., van Es, S. C., Boon, E., Huisman, M. C., van Grieken, N. C. T., Dekker, H., van Dongen, G. A. M. S., Vugts, D. J., Boellaard, R., van Herpen, C. M. L., de Vries, E. G. E., Oyen, W. J. G., Brouwers, A. H., Verheul, H. M. W., Hoekstra, O. S., der Houven van Oordt, C. W. Menke-van

“…Missing Electronic Supplementary Materials…”
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Chromosomal copy number based stratification of gastric cancer has added prognostic value to Lauren's histological classification by Biesma, H D, Soeratram, T T D, van Essen, H F, Egthuijsen, J M P, Poell, J B, van Dijk, E, Meershoek-Klein Kranenbarg, E, Hartgrink, H H, van de Velde, C J H, van de Wiel, M A, Ylstra, B, van Grieken, N C T

“…The Cancer Genome Atlas (TCGA) recognizes four molecular subgroups of gastric cancer: Epstein-Barr virus (EBV) positive, microsatellite instable (MSI),…”
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MiR expression profiles of paired primary colorectal cancer and metastases by next-generation sequencing by Neerincx, M, Sie, D L S, van de Wiel, M A, van Grieken, N C T, Burggraaf, J D, Dekker, H, Eijk, P P, Ylstra, B, Verhoef, C, Meijer, G A, Buffart, T E, Verheul, H M W

“…MicroRNAs (miRs) have been recognized as promising biomarkers. It is unknown to what extent tumor-derived miRs are differentially expressed between primary…”
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Oesophageal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up by Obermannová, R., Alsina, M., Cervantes, A., Leong, T., Lordick, F., Nilsson, M., van Grieken, N.C.T., Vogel, A., Smyth, E.C.

“…•This ESMO Clinical Practice Guideline provides key recommendations for managing oesophageal cancer.•The guideline covers clinical and pathological diagnosis,…”
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Epidemiological trends of pre-malignant gastric lesions: a long-term nationwide study in the Netherlands by de Vries, A C, Meijer, G A, Looman, C W N, Casparie, M K, Hansen, B E, van Grieken, N C T, Kuipers, E J

“…Background:The pre-malignant gastric lesions atrophic gastritis (AG), intestinal metaplasia (IM) and dysplasia (DYS) have long been identified as principal…”
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Small bowel adenocarcinoma copy number profiles are more closely related to colorectal than to gastric cancers by Haan, J.C., Buffart, T.E., Eijk, P.P., van de Wiel, M.A., van Wieringen, W.N., Howdle, P.D., Mulder, C.J.J., van de Velde, C.J., Quirke, P., Nagtegaal, I.D., van Grieken, N.C.T., Grabsch, H., Meijer, G.A., Ylstra, B.

“…Small bowel adenocarcinoma (SBA) is a rare cancer and consequently, the options for clinical trials are limited. As they are treated according to either a…”
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MSI as a predictive factor for treatment outcome of gastroesophageal adenocarcinoma by van Velzen, M.J.M., Derks, S., van Grieken, N.C.T., Haj Mohammad, N., van Laarhoven, H.W.M.

“…•MSI-H has been associated with favorable survival outcomes in gastroesophageal cancer.•In gastroesophageal cancer, MSI-H tumors show resistance to specific…”
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Gastric cancers in young and elderly patients show different genomic profiles by Buffart, TE, Carvalho, B, Hopmans, E, Brehm, V, Kranenbarg, E Klein, Schaaij-Visser, TBM, Eijk, PP, van Grieken, NCT, Ylstra, B, van de Velde, CJH, Meijer, GA

“…Although most gastric cancers occur in elderly patients, a substantial number of cases of this common disease occur in young patients. Gastric cancer is a…”
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Early outcomes from the Dutch Upper Gastrointestinal Cancer Audit by Busweiler, L. A. D., Wijnhoven, B. P. L., van Berge Henegouwen, M. I., Henneman, D., van Grieken, N. C. T., Wouters, M. W. J. M., van Hillegersberg, R., van Sandick, J. W.

“…Background In 2011, the Dutch Upper Gastrointestinal Cancer Audit (DUCA) group began nationwide registration of all patients undergoing surgery with the…”
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Adjuvant chemotherapy is superior to chemoradiation after D2 surgery for gastric cancer in the per-protocol analysis of the randomized CRITICS trial by de Steur, W.O., van Amelsfoort, R.M., Hartgrink, H.H., Putter, H., Meershoek-Klein Kranenbarg, E., van Grieken, N.C.T., van Sandick, J.W., Claassen, Y.H.M., Braak, J.P.B.M., Jansen, E.P.M., Sikorska, K., van Tinteren, H., Walraven, I., Lind, P., Nordsmark, M., van Berge Henegouwen, M.I., van Laarhoven, H.W.M., Cats, A., Verheij, M., van de Velde, C.J.H.

“…The Intergroup 0116 and the MAGIC trials changed clinical practice for resectable gastric cancer in the Western world. In these trials, overall survival…”
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A Crohn's disease patient with pustules and fever by Bouma, G, Neve, S, van Grieken, N C T, Mulder, C J, Stoof, T J

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