Search Results - "van Grevenstein, W. M. U."
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Imatinib treatment of poor prognosis mesenchymal-type primary colon cancer: a proof-of-concept study in the preoperative window period (ImPACCT)
Published in BMC cancer (19-04-2017)“…The identification of four Consensus Molecular Subtypes (CMS1-4) of colorectal cancer forms a new paradigm for the design and evaluation of subtype-directed…”
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Improving clinical management of colon cancer through CONNECTION, a nation-wide colon cancer registry and stratification effort (CONNECTION II trial): rationale and protocol of a single arm intervention study
Published in BMC cancer (18-08-2020)“…It is estimated that around 15-30% of patients with early stage colon cancer benefit from adjuvant chemotherapy. We are currently not capable of upfront…”
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3
Inflammatory cytokines stimulate the adhesion of colon carcinoma cells to mesothelial monolayers
Published in Digestive diseases and sciences (01-10-2007)“…Surgical handling of the peritoneum causes an inflammatory reaction, during which a potentially lethal cocktail of active mediators is produced, including…”
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Operative notes do not reflect reality in laparoscopic cholecystectomy
Published in British journal of surgery (01-10-2011)“…Background: Operative notes represent an essential element in safe patient care and should therefore be clear and accurate. This comparative study examined…”
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Organoids from colorectal peritoneal metastases as a platform for improving hyperthermic intraperitoneal chemotherapy
Published in British journal of surgery (01-09-2019)“…Background Patients with peritoneal metastases from colorectal cancer have a poor prognosis. If the intraperitoneal tumour load is limited, patients may be…”
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Pathological Complete Response Following Different Neoadjuvant Treatment Strategies for Locally Advanced Rectal Cancer: A Systematic Review and Meta-analysis
Published in Annals of surgical oncology (01-10-2020)“…Background Pathological complete response (pCR) following neoadjuvant treatment for locally advanced rectal cancer (LARC) is associated with better survival,…”
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Histopathological and molecular classification of colorectal cancer and corresponding peritoneal metastases
Published in British journal of surgery (01-01-2018)“…Background Patients with colorectal peritoneal carcinomatosis have a very poor prognosis. The recently developed consensus molecular subtype (CMS)…”
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Perioperative Systemic Therapy Versus Cytoreductive Surgery and HIPEC Alone for Resectable Colorectal Peritoneal Metastases: Patient-Reported Outcomes of a Randomized Phase II Trial
Published in Annals of surgical oncology (01-05-2023)“…Background As part of a randomized phase II trial in patients with isolated resectable colorectal peritoneal metastases (CPMs), the present study compared…”
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A multicentre cohort study of serum and peritoneal biomarkers to predict anastomotic leakage after rectal cancer resection
Published in Colorectal disease (01-01-2020)“…Aim Anastomotic leakage (AL) is one of the most feared complications after rectal resection. This study aimed to assess a combination of biomarkers for early…”
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10
Transanal total mesorectal excision: how are we doing so far?
Published in Colorectal disease (01-07-2019)“…Aim This subgroup analysis of a prospective multicentre cohort study aims to compare postoperative morbidity between transanal total mesorectal excision…”
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Adhesion formation after surgery for locally advanced colonic cancer in the COLOPEC trial
Published in British journal of surgery (15-03-2022)Get full text
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Association between socioeconomic status, surgical treatment and mortality in patients with colorectal cancer
Published in British journal of surgery (01-08-2014)“…Background High socioeconomic status is associated with better survival in colorectal cancer (CRC). This study investigated whether socioeconomic status is…”
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The effect of neoadjuvant short-course radiotherapy and delayed surgery versus chemoradiation on postoperative outcomes in locally advanced rectal cancer patients – A propensity score matched nationwide audit-based study
Published in European journal of surgical oncology (01-09-2020)“…To investigate differences in postoperative outcomes between short-course radiotherapy and delayed surgery (SCRT-delay) and chemoradiation (CRT) in patients…”
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14
Crew Resource Management Training for Surgical Teams, A Fragmented Landscape
Published in Journal of surgical education (01-11-2021)“…Medical Crew Resource Management (CRM) training courses are designed to increase patient safety by reducing the effects of human errors. These training courses…”
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Impact of Dose-Escalated Chemoradiation on Quality of Life in Patients With Locally Advanced Rectal Cancer: 2-Year Follow-Up of the Randomized RECTAL-BOOST Trial
Published in International journal of radiation oncology, biology, physics (01-03-2022)“…Dose-escalated chemoradiation (CRT) for locally advanced rectal cancer did not result in higher complete response rates but initiated more tumor regression in…”
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Influence of Per-Operative Serum on Tumour Cell Adhesion in Vitro
Published in The Journal of adhesion (28-02-2007)“…In case of massive tissue damage, the ensuing inflammatory reaction produces a potentially lethal cocktail of active mediators. Beside the influence of these…”
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Vacuum-assisted closure therapy for infected perineal wounds after abdominoperineal resection. A retrospective cohort study
Published in International journal of surgery (London, England) (01-02-2016)“…Abstract Introduction Perineal wound complications are a main problem after abdominoperineal resection (APR). There is little evidence concerning perineal…”
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The post-surgical inflammatory response provokes enhanced tumour recurrence: a crucial role for neutrophils
Published in Digestive surgery (01-01-2007)“…Peritoneal trauma activates a cascade of peritoneal defence mechanisms responsible for postoperative intra-abdominal tumour recurrence. After peritoneal…”
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A small mammal model of tumour implantation, dissemination and growth factor expression after partial hepatectomy
Published in European journal of surgical oncology (01-04-2008)“…Abstract Background Surgical resection remains the most effective therapy for metastatic colorectal cancer confined to the liver, although the extrahepatic…”
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Differences in patient- and tumor characteristics, treatment and survival between patients with screen-detected versus clinically detected colorectal peritoneal metastases
Published in European journal of surgical oncology (01-01-2025)“…Screening for colorectal cancer has been implemented to improve cancer-specific survival. This study aims to compare patient- and tumor characteristics,…”
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