Search Results - "van Geel, AN"

Clinical relevance of melanoma micrometastases (<0.1 mm) in sentinel nodes: are these nodes to be considered negative? by van Akkooi, ACJ, de Wilt, JHW, Verhoef, C, Schmitz, PIM, van Geel, AN, Eggermont, AMM, Kliffen, M

“…As only about 20% of sentinel node (SN) positive melanoma patients have additional non-SN lymph node involvement in the Completion Lymph Node Dissection (CLND)…”
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Outcome and prognostic factor analysis of 217 consecutive isolated limb perfusions with tumor necrosis factor‐α and melphalan for limb‐threatening soft tissue sarcoma by Grunhagen, Dirk J., de Wilt, Johannes H. W., Graveland, Wilfried J., Verhoef, Cornelis, van Geel, Albertus N., Eggermont, Alexander M. M.

“…BACKGROUND Extensive and mutilating surgery is often required for locally advanced soft tissue sarcoma (STS) of the limb. As it has become apparent that…”
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A randomised phase II study on neo-adjuvant chemotherapy for ‘high-risk’ adult soft-tissue sarcoma by Gortzak, E, Azzarelli, A, Buesa, J, Bramwell, V.H.C, van Coevorden, F, van Geel, A.N, Ezzat, A, Santoro, A, Oosterhuis, J.W, van Glabbeke, M, Kirkpatrick, A, Verweij, J

“…The aim of this study was to examine the strategy, feasibility and outcome of neo-adjuvant chemotherapy, with doxorubicin and ifosfamide, in adult patients…”
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One hundred consecutive isolated limb perfusions with TNF-alpha and melphalan in melanoma patients with multiple in-transit metastases by Grünhagen, Dirk J, Brunstein, Flavia, Graveland, Wilfried J, van Geel, Albertus N, de Wilt, Johannes H W, Eggermont, Alexander M M

“…The aim of this study is to describe the experience with 100 TNF-based ILP for locally advanced melanoma and to determine prognostic factors for response, time…”
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Survival and prognostic factors in BRCA1-associated breast cancer by Brekelmans, C. T. M., Seynaeve, C., Menke-Pluymers, M., Brüggenwirth, H. T., Tilanus-Linthorst, M. M. A., Bartels, C. C. M., Kriege, M., van Geel, A. N., Crepin, C. M. G., Blom, J. C., Meijers-Heijboer, H., Klijn, J. G. M.

“…Background: Studies comparing survival in BRCA1-associated and sporadic breast cancer (BC) report inconsistent results and frequently concern small sample…”
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High positive sentinel node identification rate by EORTC melanoma group protocol prognostic indicators of metastatic patterns after sentinel node biopsy in melanoma by VAN AKKOOI, A. C. J, DE WILT, J. H. W, VERHOEF, C, GRAUELAND, W. J, VAN GEEL, A. N, KLIFFEN, M, EGGERMONT, A. M. M

“…Methods to work-up sentinel nodes (SN) vary considerably between institutes. This single institution study evaluated the positive SN-identification rate of the…”
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Presymptomatic DNA testing and prophylactic surgery in families with a BRCA1 or BRCA2 mutation by Meijers-Heijboer, EJ, Verhoog, LC, Brekelmans, CTM, Seynaeve, C, Tilanus-Linthorst, MMA, Wagner, A, Dukel, L, Devilee, P, van den Ouweland, AMW, van Geel, AN, Klijn, JGM

“…Germline mutations in the BRCA1 and BRCA2 genes highly predispose to breast and ovarian cancer. In families with BRCA1 or BRCA2 mutations, identification of…”
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Effect of a combined surgery, re-irradiation and hyperthermia therapy on local control rate in radio-induced angiosarcoma of the chest wall by Linthorst, M., van Geel, A.N., Baartman, E.A., Oei, S.B., Ghidey, W., van Rhoon, G.C., van der Zee, J.

“…Purpose Radiation-induced angiosarcoma (RAS) of the chest wall/breast has a poor prognosis due to the high percentage of local failures. The efficacy and side…”
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Effectiveness of Breast Cancer Surveillance in BRCA1/2 Gene Mutation Carriers and Women With High Familial Risk by BREKELMANS, C. T. M, SEYNAEVE, C, OBDEIJN, I. M, KLIJN, J. G. M, BARTELS, C. C. M, TILANUS-LINTHORST, M. M. A, MEIJERS-HEIJBOER, E. J, CREPIN, C. M. G, VAN GEEL, A. N, MENKE, M, VERHOOG, L. C, VAN DEN OUWELAND, A

“…Women with a high breast cancer risk due to a familial predisposition may choose between preventive surgery and regular surveillance. The effectiveness of…”
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Lung metastases from melanoma: when is surgical treatment warranted? by Leo, F, Cagini, L, Rocmans, P, Cappello, M, Geel, A N, Maggi, G, Goldstraw, P, Pastorino, U

“…Surgical treatment of lung metastases from melanoma is highly controversial as the expected outcome is much poorer than for other primary tumours and a…”
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Survival and tumour characteristics of breast-cancer patients with germline mutations of BRCA1 by Verhoog, LC, Brekelmans, CTM, Seynaeve, C, van den Bosch, LMC, Dahmen, G, van Geel, AN, Tilanus-Linthorst, MMA, Bartels, CCM, Wagner, A, van den Ouweland, A, Devilee, P, Meijers-Heijboer, EJ, Klijn, JGM

“…Hereditary breast cancer has been associated with mutations in the BRCA1 and BRCA2 genes and has a natural history different from sporadic breast cancer. We…”
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The palliative value of tumor necrosis factor α‐based isolated limb perfusion in patients with metastatic sarcoma and melanoma by Grunhagen, Dirk J., de Wilt, Johannes H. W., Graveland, Wilfried J., van Geel, Albertus N., Eggermont, Alexander M. M.

“…BACKGROUND Both patients with soft tissue sarcoma (STS) and patients with melanoma have limited treatment possibilities once the tumor has metastasized…”
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One year follow-up of women opting for presymptomatic testing for BRCA1 and BRCA2: emotional impact of the test outcome and decisions on risk management (surveillance or prophylactic surgery) by LODDER, Litanja N, FRETS, Petra G, BREKELMANS, Cecile T. M, BURGER, Curt W, NIERMEIJER, Martinus F, TRIJSBURG, R. Willem, MEIJERS-HEIJBOER, E. Johanna, KLIJN, Jan G. M, SEYNAEVE, Caroline, VAN GEEL, Albertus N, TILANUS, Madeleine M. A, BARTELS, Carina C. M, VERHOOG, Leon C

“…Genetic testing enables women at risk for hereditary breast and/or ovarian cancer to find out whether they have inherited the gene mutation (BRCA1/BRCA2), and…”
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Multicentre study of ultrasonographically guided axillary node biopsy in patients with breast cancer by de Kanter, A. Y., van Eijck, C. H. J., van Geel, A. N., Kruijt, R. H., Henzen, S. C., Paul, M. A., Eggermont, A. M. M., Wiggers, T.

“…Background: Axillary lymph node dissection is still performed as a staging procedure since lymph node status is the most important prognostic factor in…”
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Ipsilateral breast tumour recurrence in hereditary breast cancer following breast-conserving therapy by Seynaeve, C, Verhoog, L.C, van de Bosch, L.M.C, van Geel, A.N, Menke-Pluymers, M, Meijers-Heijboer, E.J, van den Ouweland, A.M.W, Wagner, A, Creutzberg, C.L, Niermeijer, M.F, Klijn, J.G.M, Brekelmans, C.T.M

“…The overall rate of an ipsilateral breast tumour recurrence (IBTR) after breast-conserving therapy (BCT) ranges from 1% to 2% per year. Risk factors include…”
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Metastasectomy in renal cell carcinoma: A multicenter retrospective analysis by van der Poel, H G, Roukema, J A, Horenblas, S, van Geel, A N, Debruyne, F M

“…In 60-70% of patients with renal cell carcinoma (RCC), metastases develop in the course of the disease. In the present analysis, the surgical management of…”
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Survival in Hereditary Breast Cancer Associated With Germline Mutations of BRCA2 by VERHOOG, L. C, BREKELMANS, C. T. M, VAN DEN OUWELAND, A. M. W, MEIJERS-HEIJBOER, E. J, KLIJN, J. G. M, SEYNAEVE, C, DAHMEN, G, VAN GEEL, A. N, BARTELS, C. C. M, TILANUS-LINTHORST, M. M. A, WAGNER, A, DEVILEE, P, HALLEY, D. J. J

“…Breast cancer in BRCA1 and BRCA2 gene-mutation carriers may differ from so-called sporadic breast cancer in clinical features and behavior. These potential…”
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Efficacy of repeat isolated limb perfusions with tumor necrosis factor alpha and melphalan for multiple in-transit metastases in patients with prior isolated limb perfusion failure by Grünhagen, Dirk J, van Etten, Boudewijn, Brunstein, Flavia, Graveland, Wilfried J, van Geel, Albertus N, de Wilt, Johannes H W, Eggermont, Alexander M M

“…Isolated limb perfusion (ILP) is an effective treatment modality for multiple in-transit melanoma metastases confined to the limb. Recurrences after ILP,…”
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Morbidity of immediate breast reconstruction (IBR) after mastectomy by a subpectorally placed silicone prosthesis:the adverse effect of radiotherapy by Contant, C.M.E., van Geel, A.N., van der Holt, B., Griep, C., Tjong Joe Wai, R., Wiggers, Th

“…Aims This study evaluates the incidence of local complications after immediate breast reconstruction (IBR) following mastectomy with a subpectorally placed…”
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Isolated limb perfusions with tumor necrosis factor and melphalan for locally recurrent soft tissue sarcoma in previously irradiated limbs by Lans, T E, Grünhagen, D J, de Wilt, J H W, van Geel, A N, Eggermont, A M M

“…Recurrent extremity soft tissue sarcoma (STS) in a previously operated and irradiated area can usually be managed only by amputation. Tumor necrosis factor…”
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