Search Results - "van Even, P"
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Lung collagen synthesis and deposition in tight-skin mice with genetic emphysema
Published in Experimental and molecular pathology (01-04-1992)“…The tight-skin (Tsk) mouse is a genetic model of pulmonary emphysema linked to a deficiency of serum antielastase. In this mouse occurrence of connective…”
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Cardiac collagen changes during the development of right ventricular hypertrophy in tight-skin mice with emphysema
Published in Experimental and molecular pathology (01-04-1994)“…The tight-skin (Tsk) mouse is a genetic model of pulmonary emphysema. In this mouse, right ventricular hypertrophy (RVH) starts to develop at approximately 8…”
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Different evolution of emphysema in two strains of mice with similar serum antielastase deficit
Published in Annals of the New York Academy of Sciences (01-05-1991)Get more information
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Development of cor pulmonale in tight-skin mice with genetic emphysema
Published in Annals of the New York Academy of Sciences (1991)Get more information
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Increased myocardial capillary density in dogs with experimental emphysema
Published in Laboratory investigation (01-05-1984)“…In the hearts of control beagle dogs, capillary density in the right ventricle was found to be similar to that of the subendocardium of the left ventricle but…”
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A 16-month study of the development of genetic emphysema in tight-skin mice
Published in The American review of respiratory disease (01-01-1989)“…The tight-skin (tsk) mouse has been recently proposed as a model of genetically determined emphysema. In the present study, the development of this lung lesion…”
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Increase in number and decrease in size of mitochondrial profiles in myocytes of the right ventricle of dogs with experimental emphysema
Published in The American review of respiratory disease (01-09-1986)“…An ultrastructural study of the myocardium in control dogs and in dogs with papain-induced emphysema of 6 months duration without signs of right ventricular…”
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Tsk mice with genetic emphysema. Right ventricular hypertrophy occurs without hypertrophy of muscular pulmonary arteries or muscularization of arterioles
Published in The American review of respiratory disease (01-08-1990)“…The causes for the development of right ventricular hypertrophy (RVH) in emphysema are not fully understood. In the 1960s, studies of RVH in association with…”
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The effect of physical exercise on elastase-induced emphysema in hamsters
Published in The American review of respiratory disease (01-12-1979)Get more information
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A scanning electron microscopic investigation of genetic emphysema in tight-skin, pallid, and beige mice, three different C57 BL/6J mutants
Published in Laboratory investigation (01-02-1996)“…Three mutants of the C57 BL/6J strain, i.e., the tight-skin (Tsk), pallid (pa), and beige (bg) mice have been reported to develop spontaneous emphysema…”
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The pallid mouse. A model of genetic alpha 1-antitrypsin deficiency
Published in Laboratory investigation (01-02-1993)“…The current hypothesis of pulmonary emphysema is based on an alteration of the protease-antiprotease balance within the lower respiratory tract. This…”
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Neutrophil recruitment into the lungs is associated with increased lung elastase burden, decreased lung elastin, and emphysema in alpha 1 proteinase inhibitor-deficient mice
Published in Laboratory investigation (01-08-1996)“…The possibility that polymorphonuclear leukocytes (PMN) recruited into the lung have the capability to damage alveolar septa was investigated in several…”
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Early Induction of Angiotensin I-Converting Enzyme in Rat Carotid Artery After Balloon Injury
Published in Hypertension (Dallas, Tex. 1979) (01-08-1997)“…Several studies have demonstrated the effectiveness of angiotensin I-converting enzyme (ACE) inhibitors in preventing the neointima formation found after…”
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Cardiac and vascular effects of chronic angiotensin converting enzyme inhibition at subantihypertensive doses
Published in Journal of hypertension. Supplement (01-08-1992)“…We performed two sets of experiments in order to prevent or to regress cardiac and vascular hypertrophy, using antihypertensive and subantihypertensive doses…”
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A biochemical and morphological investigation of the early development of genetic emphysema in tight-skin mice
Published in Experimental and molecular pathology (01-06-1989)“…The tight-skin (Tsk) mouse has recently been proposed as a genetic model of emphysema. In the present study, the development of emphysema was investigated in…”
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Immunoelectron-microscopic demonstration of elastase in emphysematous lungs of tight-skin mice
Published in Experimental and molecular pathology (01-08-1989)“…The tight-skin (Tsk) mouse has recently been proposed as a genetic model of emphysema. A morphometric study has shown that emphysema develops quickly, between…”
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The effect of lung growth on the evolution of elastase-induced emphysema in the hamster
Published in Lung (01-12-1982)Get full text
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Serum antielastase deficiency in tight-skin mice with genetic emphysema
Published in Experimental and molecular pathology (01-02-1990)“…The tight-skin (Tsk) mouse is a model of genetically determined emphysema. The cause for the development of the lung lesion is unknown. In the present study we…”
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Vascular and cardiac protection by ramipril in spontaneously hypertensive rats: prevention versus regression study
Published in British journal of clinical practice. Supplement (01-07-1996)“…The effect of chronic oral treatment with the angiotensin converting enzyme (ACE) inhibitor ramipril at antihypertensive and sub-antihypertensive doses, on…”
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