Search Results - "van Erp, M. G."
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Association of Thalamic Dysconnectivity and Conversion to Psychosis in Youth and Young Adults at Elevated Clinical Risk
Published in JAMA psychiatry (Chicago, Ill.) (01-09-2015)“…Severe neuropsychiatric conditions, such as schizophrenia, affect distributed neural computations. One candidate system profoundly altered in chronic…”
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Mapping brain asymmetry in health and disease through the ENIGMA consortium
Published in Human brain mapping (01-01-2022)“…Left–right asymmetry of the human brain is one of its cardinal features, and also a complex, multivariate trait. Decades of research have suggested that brain…”
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Cerebello-thalamo-cortical hyperconnectivity as a state-independent functional neural signature for psychosis prediction and characterization
Published in Nature communications (21-09-2018)“…Understanding the fundamental alterations in brain functioning that lead to psychotic disorders remains a major challenge in clinical neuroscience. In…”
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Multimodal neuromarkers in schizophrenia via cognition-guided MRI fusion
Published in Nature communications (02-08-2018)“…Cognitive impairment is a feature of many psychiatric diseases, including schizophrenia. Here we aim to identify multimodal biomarkers for quantifying and…”
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White matter microstructural alterations across four major psychiatric disorders: mega-analysis study in 2937 individuals
Published in Molecular psychiatry (01-04-2020)“…Identifying both the commonalities and differences in brain structures among psychiatric disorders is important for understanding the pathophysiology…”
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Dentate gyrus volume deficit in schizophrenia
Published in Psychological medicine (01-06-2020)“…Schizophrenia is associated with robust hippocampal volume deficits but subregion volume deficits, their associations with cognition, and contributing genes…”
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Local molecular and global connectomic contributions to cross-disorder cortical abnormalities
Published in Nature communications (10-08-2022)“…Numerous brain disorders demonstrate structural brain abnormalities, which are thought to arise from molecular perturbations or connectome miswiring. The…”
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Multisite reliability of MR-based functional connectivity
Published in NeuroImage (Orlando, Fla.) (01-02-2017)“…Recent years have witnessed an increasing number of multisite MRI functional connectivity (fcMRI) studies. While multisite studies provide an efficient way to…”
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Brown adipose tissue quantification in human neonates using water-fat separated MRI
Published in PloS one (30-10-2013)“…There is a major resurgence of interest in brown adipose tissue (BAT) biology, particularly regarding its determinants and consequences in newborns and…”
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Early and Late Neurodevelopmental Influences in the Prodrome to Schizophrenia: Contributions of Genes, Environment, and Their Interactions
Published in Schizophrenia bulletin (01-01-2003)“…Both early (i.e., pre- and perinatal periods) and late (i.e., adolescent period) neurodevelopmental processes are thought to participate in the etiology and…”
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Huntington’s disease cerebrospinal fluid seeds aggregation of mutant huntingtin
Published in Molecular psychiatry (01-11-2015)“…Huntington’s disease (HD), a progressive neurodegenerative disease, is caused by an expanded CAG triplet repeat producing a mutant huntingtin protein (mHTT)…”
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Differences in fractional anisotropy between the patients with schizophrenia and healthy comparison subjects
Published in Molecular psychiatry (01-04-2020)Get full text
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Brain surface contraction mapped in first-episode schizophrenia: a longitudinal magnetic resonance imaging study
Published in Molecular psychiatry (01-10-2009)“…Schizophrenia is associated with structural brain abnormalities, but the timing of onset and course of these changes remains unclear. Longitudinal magnetic…”
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Analysis of miR-137 expression and rs1625579 in dorsolateral prefrontal cortex
Published in Journal of psychiatric research (01-09-2013)“…Abstract MicroRNAs (miRNAs) are small non-coding RNAs that act as potent regulators of gene expression. A recent GWAS reported the rs1625579 SNP, located…”
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Multiscale neural gradients reflect transdiagnostic effects of major psychiatric conditions on cortical morphology
Published in Communications biology (27-09-2022)“…It is increasingly recognized that multiple psychiatric conditions are underpinned by shared neural pathways, affecting similar brain systems. Here, we carried…”
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FreeSurfer‐based segmentation of hippocampal subfields: A review of methods and applications, with a novel quality control procedure for ENIGMA studies and other collaborative efforts
Published in Human brain mapping (01-01-2022)“…Structural hippocampal abnormalities are common in many neurological and psychiatric disorders, and variation in hippocampal measures is related to cognitive…”
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Elucidating a Magnetic Resonance Imaging-Based Neuroanatomic Biomarker for Psychosis: Classification Analysis Using Probabilistic Brain Atlas and Machine Learning Algorithms
Published in Biological psychiatry (1969) (01-12-2009)“…Background No objective diagnostic biomarkers or laboratory tests have yet been developed for psychotic illness. Magnetic resonance imaging (MRI) studies…”
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Developmental disruptions in neural connectivity in the pathophysiology of schizophrenia
Published in Development and psychopathology (2008)“…Schizophrenia has been thought of as a disorder of reduced functional and structural connectivity. Recent advances in neuroimaging techniques such as…”
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Reliability of neuroanatomical measurements in a multisite longitudinal study of youth at risk for psychosis
Published in Human brain mapping (01-05-2014)“…Multisite longitudinal neuroimaging designs are used to identify differential brain structural change associated with onset or progression of disease. The…”
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Reliability of functional magnetic resonance imaging activation during working memory in a multi-site study: Analysis from the North American Prodrome Longitudinal Study
Published in NeuroImage (Orlando, Fla.) (15-08-2014)“…Multi-site neuroimaging studies offer an efficient means to study brain functioning in large samples of individuals with rare conditions; however, they present…”
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