Search Results - "van Ens, Diede"
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Actomyosin contractility requirements and reciprocal cell–tissue mechanics for cancer cell invasion through collagen-based channels
Published in The European physical journal. E, Soft matter and biological physics (2022)“…The interstitial tumor microenvironment is composed of heterogeneously organized collagen-rich porous networks as well as channel-like structures and…”
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PD-L1 siRNA-mediated silencing in acute myeloid leukemia enhances anti-leukemic T cell reactivity
Published in Bone marrow transplantation (Basingstoke) (01-12-2020)“…Acute myeloid leukemia (AML) is an immune-susceptible malignancy, as demonstrated by its responsiveness to allogeneic stem cell transplantation (alloSCT)…”
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Hypoxia-Inducible Factor 1 Alpha Is Dispensable for Host Defense of Group B Streptococcus Colonization and Infection
Published in Journal of innate immunity (01-11-2021)“…Group B Streptococcus (GBS) is a leading cause of neonatal morbidity and mortality, and the primary source of exposure is the maternal vagina. Intrapartum…”
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Clinically applicable CD34+-derived blood dendritic cell subsets exhibit key subset-specific features and potently boost anti-tumor T and NK cell responses
Published in Cancer Immunology, Immunotherapy (01-11-2021)“…Allogeneic stem cell transplantation (alloSCT), following induction chemotherapy, can be curative for hemato-oncology patients due to powerful…”
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Increased peritoneal TGF-β1 is associated with ascites-induced NK-cell dysfunction and reduced survival in high-grade epithelial ovarian cancer
Published in Frontiers in immunology (23-09-2024)“…Natural killer (NK) cell therapy represents an attractive immunotherapy approach against recurrent epithelial ovarian cancer (EOC), as EOC is sensitive to NK…”
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Human CD34+-derived complete plasmacytoid and conventional dendritic cell vaccine effectively induces antigen-specific CD8+ T cell and NK cell responses in vitro and in vivo
Published in Cellular and molecular life sciences : CMLS (01-10-2023)“…Allogeneic stem cell transplantation (alloSCT) can be curative for hemato-oncology patients due to effective graft-versus-tumor immunity. However, relapse…”
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Interleukin-1β induces trained innate immunity in human hematopoietic progenitor cells in vitro
Published in Stem cell reports (01-11-2024)“…Innate immune cells can develop a long-lasting hyperresponsive phenotype, termed trained immunity, mediated by epigenetic and metabolic reprogramming. In mice,…”
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