Search Results - "van Engelen, Jacqueline G.M."
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The probabilistic aggregate consumer exposure model (PACEM): Validation and comparison to a lower-tier assessment for the cyclic siloxane D5
Published in Environment international (01-06-2015)“…Current practice of chemical risk assessment for consumer product ingredients still rarely exercises the aggregation of multi-source exposure. However,…”
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Effect of Coexposure to Methyl Ethyl Ketone (MEK) onn-Hexane Toxicokinetics in Human Volunteers
Published in Toxicology and applied pharmacology (01-06-1997)“…In order to study the effects of methyl ethyl ketone (MEK) on the toxicokinetics ofn-hexane and, in particular, the formation of 2,5-hexanedione fromn-hexane…”
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3
Consumer product in vitro digestion model: Bioaccessibility of contaminants and its application in risk assessment
Published in Regulatory toxicology and pharmacology (01-03-2006)“…This paper describes the applicability of in vitro digestion models as a tool for consumer products in (ad hoc) risk assessment. In current risk assessment,…”
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Results of a cosmetovigilance survey in The Netherlands
Published in Contact dermatitis (01-03-2013)“…Background. Cosmetic products contribute considerably to the incidence of contact dermatitis. In response to a resolution of the Council of Europe, the…”
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Glucuronidation of thyroid hormone in rat liver: effects of in vivo treatment with microsomal enzyme inducers and in vitro assay conditions
Published in Endocrinology (Philadelphia) (01-11-1993)“…We investigated the effects of in vivo treatment with different microsomal enzyme inducers, including clofibrate (CLOF), hexachlorobenzene (HCB),…”
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Thyroxine and 3,3',5-triiodothyronine are glucuronidated in rat liver by different uridine diphosphate-glucuronyltransferases
Published in Endocrinology (Philadelphia) (01-02-1991)“…Male Wistar rats were treated with 50 mg 3,3',4,4'-tetrachlorobiphenyl (TCB)/kg BW or vehicle. After 4 days, the livers were isolated and perfused for 90 min…”
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Effect of coexposure to methyl ethyl ketone (MEK) on n-hexane toxicokinetics in human volunteers
Published in Toxicology and applied pharmacology (01-06-1997)“…In order to study the effects of methyl ethyl ketone (MEK) on the toxicokinetics of n-hexane and, in particular, the formation of 2,5-hexanedione from n-hexane…”
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8
Determination of 2,5-hexanedione, a metabolite of n-hexane, in urine: evaluation and application of three analytical methods
Published in Journal of chromatography. Biomedical applications (19-05-1995)“…Three methods for the determination of 2,5-hexanedione (2,5-HD) in urine were compared in order to assess their applicability for toxicokinetic studies and…”
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