Search Results - "van Eijs, Mick J. M."
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Immunosuppression for immune-related adverse events during checkpoint inhibition: an intricate balance
Published in NPJ precision oncology (12-05-2023)“…Immune checkpoint inhibitors (ICIs) have changed perspectives for patients with cancer, but come with severe immune-related adverse events (irAEs). To prevent…”
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Toxicity-specific peripheral blood T and B cell dynamics in anti-PD-1 and combined immune checkpoint inhibition
Published in Cancer Immunology, Immunotherapy (01-12-2023)“…Immune checkpoint inhibitors (ICI) have revolutionized the treatment landscape of advanced malignancies, but come with a diverse spectrum of immune-related…”
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In vitro T cell responses to PD-1 blockade are reduced by IFN-α but do not predict therapy response in melanoma patients
Published in Cancer Immunology, Immunotherapy : CII (05-07-2024)“…PD-1 blockade therapy has revolutionized melanoma treatment, but still not all patients benefit and pre-treatment identification of those patients is…”
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Hematologic malignancies following immune checkpoint inhibition for solid tumors
Published in Cancer Immunology, Immunotherapy (01-01-2023)“…Immune checkpoint inhibition (ICI) can induce durable responses in patients with advanced malignancies. Three cases of hematological neoplasia following ICI…”
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Innovative Perspective: Gadolinium-Free Magnetic Resonance Imaging in Long-Term Follow-Up after Kidney Transplantation
Published in Frontiers in physiology (16-05-2017)“…Since the mid-1980s magnetic resonance imaging (MRI) has been investigated as a non- or minimally invasive tool to probe kidney allograft function. Despite…”
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Physical activity and checkpoint inhibition: association with toxicity and survival
Published in JNCI : Journal of the National Cancer Institute (05-04-2024)“…Although animal experiments suggest beneficial effects of physical activity (PA) on antitumor immunity, little is known about the effects of PA on immune…”
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Clinical and translational attributes of immune-related adverse events
Published in Nature cancer (15-02-2024)“…With immune checkpoint inhibitors (ICIs) becoming the mainstay of treatment for many cancers, managing their immune-related adverse events (irAEs) has become…”
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Response to checkpoint inhibition and targeted therapy in melanoma patients with concurrent haematological malignancies
Published in European journal of cancer (1990) (01-06-2023)“…Patients diagnosed with haematologic malignancies (HMs) have a higher risk of developing subsequent solid tumours, such as melanoma. Patients with HM were…”
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Highly multiplexed spatial analysis identifies tissue-resident memory T cells as drivers of ulcerative and immune checkpoint inhibitor colitis
Published in iScience (20-10-2023)“…Colitis is a prevalent adverse event associated with immune checkpoint inhibitor (ICI) therapy with similarities to inflammatory bowel disease. Incomplete…”
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Corticosteroids and other immunosuppressants for immune-related adverse events and checkpoint inhibitor effectiveness in melanoma
Published in European journal of cancer (1990) (01-08-2024)“…Recent studies indicate an association between immunosuppression for immune-related adverse events (irAEs) and impaired survival in patients who received…”
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Association between physical activity, immune-related adverse events, and mortality in patients undergoing immune checkpoint inhibition
Published in Journal of clinical oncology (01-06-2023)“…2643 Background: Immune checkpoint inhibitors (ICIs) have improved prospects for some, but not all patients with cancer and frequently induce severe…”
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Student-driven education; catalyst of change in medical curriculum
Published in Nederlands tijdschrift voor geneeskunde (30-08-2018)“…Changing healthcare requires future physicians to have some basic knowledge of fields related to medicine. There is also a growing need for multidisciplinary…”
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