Search Results - "van Eif, Vincent W.W."

Genome-Wide Analysis Identifies an Essential Human TBX3 Pacemaker Enhancer by van Eif, Vincent W.W., Protze, Stephanie I., Bosada, Fernanda M., Yuan, Xuefei, Sinha, Tanvi, van Duijvenboden, Karel, Ernault, Auriane C., Mohan, Rajiv A., Wakker, Vincent, de Gier-de Vries, Corrie, Hooijkaas, Ingeborg B., Wilson, Michael D., Verkerk, Arie O., Bakkers, Jeroen, Boukens, Bastiaan J., Black, Brian L., Scott, Ian C., Christoffels, Vincent M.

“…RATIONALE:The development and function of the pacemaker cardiomyocytes of the sinoatrial node (SAN), the leading pacemaker of the heart, are tightly controlled…”
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Transcriptional regulation of the cardiac conduction system by van Eif, Vincent W. W., Devalla, Harsha D., Boink, Gerard J. J., Christoffels, Vincent M.

“…The rate and rhythm of heart muscle contractions are coordinated by the cardiac conduction system (CCS), a generic term for a collection of different…”
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Gradual differentiation and confinement of the cardiac conduction system as indicated by marker gene expression by van Eif, Vincent W.W., Stefanovic, Sonia, Mohan, Rajiv A., Christoffels, Vincent M.

“…The components of the cardiac conduction system, responsible for coordinated activation of the heart chambers, are well defined and their cells differ in gene…”
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Transcriptome analysis of mouse and human sinoatrial node cells reveals a conserved genetic program by van Eif, Vincent W W, Stefanovic, Sonia, van Duijvenboden, Karel, Bakker, Martijn, Wakker, Vincent, de Gier-de Vries, Corrie, Zaffran, Stéphane, Verkerk, Arie O, Boukens, Bas J, Christoffels, Vincent M

“…The rate of contraction of the heart relies on proper development and function of the sinoatrial node, which consists of a small heterogeneous cell population,…”
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Variant Intronic Enhancer Controls SCN10A-short Expression and Heart Conduction by Man, Joyce C.K., Bosada, Fernanda M., Scholman, Koen T., Offerhaus, Joost A., Walsh, Roddy, van Duijvenboden, Karel, van Eif, Vincent W.W., Bezzina, Connie R., Verkerk, Arie O., Boukens, Bastiaan J., Barnett, Phil, Christoffels, Vincent M.

“…Genetic variants in , encoding the neuronal voltage-gated sodium channel Na 1.8, are strongly associated with atrial fibrillation, Brugada syndrome, cardiac…”
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Intrinsic cardiac adrenergic (ICA) cell density and MAO-A activity in failing rat hearts by van Eif, Vincent W. W., Bogaards, Sylvia J. P., van der Laarse, Willem J.

“…The efficiency (work/oxygen consumption) of isolated papillary muscles from failing hearts is reduced. We investigated whether this can be due to an increase…”
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