Search Results - "van Duin, Richard W"

Neoatherosclerosis development following bioresorbable vascular scaffold implantation in diabetic and non-diabetic swine by van Ditzhuijzen, Nienke S, Kurata, Mie, van den Heuvel, Mieke, Sorop, Oana, van Duin, Richard W B, Krabbendam-Peters, Ilona, Ligthart, Jurgen, Witberg, Karen, Murawska, Magdalena, Bouma, Brett, Villiger, Martin, Garcia-Garcia, Hector M, Serruys, Patrick W, Zijlstra, Felix, van Soest, Gijs, Duncker, Dirk-Jan, Regar, Evelyn, van Beusekom, Heleen M M

“…DM remains a risk factor for poor outcome after stent-implantation, but little is known if and how DM affects the vascular response to BVS. The aim of our…”
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The microcirculation: a key player in obesity-associated cardiovascular disease by Sorop, Oana, Olver, T Dylan, van de Wouw, Jens, Heinonen, Ilkka, van Duin, Richard W, Duncker, Dirk J, Merkus, Daphne

“…It is increasingly recognized that obesity is a risk factor for microvascular disease, involving both structural and functional changes in the…”
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Perturbations in myocardial perfusion and oxygen balance in swine with multiple risk factors: a novel model of ischemia and no obstructive coronary artery disease by van de Wouw, Jens, Sorop, Oana, van Drie, Ruben W. A., van Duin, Richard W. B., Nguyen, Isabel T. N., Joles, Jaap A., Verhaar, Marianne C., Merkus, Daphne, Duncker, Dirk J.

“…Comorbidities of ischemic heart disease, including diabetes mellitus (DM), hypercholesterolemia (HC) and chronic kidney disease (CKD), are associated with…”
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Cellular, mitochondrial and molecular alterations associate with early left ventricular diastolic dysfunction in a porcine model of diabetic metabolic derangement by Heinonen, Ilkka, Sorop, Oana, van Dalen, Bas M., Wüst, Rob C. I., van de Wouw, Jens, de Beer, Vincent J., Octavia, Yanti, van Duin, Richard W. B., Hoogstrate, Youri, Blonden, Lau, Alkio, Milla, Anttila, Katja, Stubbs, Andrew, van der Velden, Jolanda, Merkus, Daphne, Duncker, Dirk J.

“…The prevalence of diabetic metabolic derangement (DMetD) has increased dramatically over the last decades. Although there is increasing evidence that DMetD is…”
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Transition from post‐capillary pulmonary hypertension to combined pre‐ and post‐capillary pulmonary hypertension in swine: a key role for endothelin by Duin, Richard W. B., Stam, Kelly, Cai, Zongye, Uitterdijk, André, Garcia‐Alvarez, Ana, Ibanez, Borja, Danser, A. H. Jan, Reiss, Irwin K. M., Duncker, Dirk J., Merkus, Daphne

“…Key points Passive, isolated post‐capillary pulmonary hypertension (PH) secondary to left heart disease may progress to combined pre‐ and post‐capillary or…”
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Coronary microvascular dysfunction after long-term diabetes and hypercholesterolemia by Sorop, Oana, van den Heuvel, Mieke, van Ditzhuijzen, Nienke S, de Beer, Vincent J, Heinonen, Ilkka, van Duin, Richard W B, Zhou, Zhichao, Koopmans, Sietse J, Merkus, Daphne, van der Giessen, Wim J, Danser, A H Jan, Duncker, Dirk Jan

“…Coronary microvascular dysfunction (CMD) has been proposed as an important component of diabetes mellitus (DM)- and hypercholesterolemia-associated coronary…”
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Multiple common comorbidities produce left ventricular diastolic dysfunction associated with coronary microvascular dysfunction, oxidative stress, and myocardial stiffening by Sorop, Oana, Heinonen, Ilkka, van Kranenburg, Matthijs, van de Wouw, Jens, de Beer, Vincent J, Nguyen, Isabel T N, Octavia, Yanti, van Duin, Richard W B, Stam, Kelly, van Geuns, Robert-Jan, Wielopolski, Piotr A, Krestin, Gabriel P, van den Meiracker, Anton H, Verjans, Robin, van Bilsen, Marc, Danser, A H Jan, Paulus, Walter J, Cheng, Caroline, Linke, Wolfgang A, Joles, Jaap A, Verhaar, Marianne C, van der Velden, Jolanda, Merkus, Daphne, Duncker, Dirk J

“…Abstract Aims More than 50% of patients with heart failure have preserved ejection fraction characterized by diastolic dysfunction. The prevalance of diastolic…”
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Pulmonary vasodilation by phosphodiesterase 5 inhibition is enhanced and nitric oxide independent in early pulmonary hypertension after myocardial infarction by van Duin, Richard W B, Houweling, Birgit, Uitterdijk, André, Duncker, Dirk J, Merkus, Daphne

“…Myocardial infarction (MI) may result in pulmonary hypertension (PH). Inhibition of phosphodiesterase 5 (PDE5), the enzyme responsible for the breakdown of…”
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Right ventricular oxygen delivery as a determinant of right ventricular functional reserve during exercise in juvenile swine with chronic pulmonary hypertension by Cai, Zongye, van Duin, Richard W B, Stam, Kelly, Uitterdijk, André, van der Velden, Jolanda, Vonk Noordegraaf, Anton, Duncker, Dirk J, Merkus, Daphne

“…Assessing right ventricular (RV) functional reserve is important for determining clinical status and prognosis in patients with pulmonary hypertension (PH). In…”
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Exercise facilitates early recognition of cardiac and vascular remodeling in chronic thromboembolic pulmonary hypertension in swine by Stam, Kelly, van Duin, Richard W B, Uitterdijk, André, Cai, Zongye, Duncker, Dirk J, Merkus, Daphne

“…Chronic thromboembolic pulmonary hypertension (CTEPH) develops in 4% of patients after pulmonary embolism and is accompanied by an impaired exercise tolerance,…”
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Structural and functional changes of the pulmonary vasculature after hypoxia exposure in the neonatal period: a new swine model of pulmonary vascular disease by de Wijs-Meijler, Daphne P M, van Duin, Richard W B, Duncker, Dirk J, Scherrer, Urs, Sartori, Claudio, Reiss, Irwin K M, Merkus, Daphne

“…Pulmonary vascular disease (PVD) represents an underestimated and increasing clinical burden not only in the neonatal period but also later in life, when…”
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Echocardiographic-Derived Strain-Area Loop of the Right Ventricle is Related to Pulmonary Vascular Resistance in Pulmonary Arterial Hypertension by Hulshof, Hugo G., van Dijk, Arie P., George, Keith P., Merkus, Daphne, Stam, Kelly, van Duin, Richard W., van Tertholen, Koen, Hopman, Maria T.E., Haddad, François, Thijssen, Dick H.J., Oxborough, David L.

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TCT-458 Delayed healing is operator procedure dependent and likely determined by smooth muscle cell proliferation rather than direct endothelial drug sensitivity by Autar, Anouchska, Faber, Nikola, Sneep, Stefan, Krabbendam-Peters, Ilona, van Duin, Richard W, Beusekom, Heleen v

“…In vivo EC restoration was studied in rabbit iliac and porcine coronary arteries using a model of controlled prior injury (B/A ratio 1.2-1.3) followed by…”
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Serial measurement of hFABP and high-sensitivity troponin I post-PCI in STEMI: how fast and accurate can myocardial infarct size and no-reflow be predicted? by Uitterdijk, André, Sneep, Stefan, van Duin, Richard W B, Krabbendam-Peters, Ilona, Gorsse-Bakker, Charlotte, Duncker, Dirk J, van der Giessen, Willem J, van Beusekom, Heleen M M

“…The objective of this study was to compare heart-specific fatty acid binding protein (hFABP) and high-sensitivity troponin I (hsTnI) via serial measurements to…”
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The effect of bioresorbable vascular scaffold implantation on distal coronary endothelial function in dyslipidemic swine with and without diabetes by van den Heuvel, Mieke, Sorop, Oana, van Ditzhuijzen, Nienke S., de Vries, René, van Duin, Richard W.B., Peters, Ilona, van Loon, Janine E., de Maat, Moniek P., van Beusekom, Heleen M., van der Giessen, Wim J., Jan Danser, A.H., Duncker, Dirk J.

“…We studied the effect of bioresorbable vascular scaffold (BVS) implantation on distal coronary endothelial function, in swine on a high fat diet without (HFD)…”
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TCT-632 Diabetes and Atherosclerosis Do Not Affect Early Degradation of Bioresorbable Vascular Scaffolds by Kurata, Mie, van Ditzhuijzen, Nienke S, Sorop, Oana, van Duin, Richard W, Krabbendam-Peters, Ilona, Veldhof, Timothy, Serruys, Patrick W, Zijlstra, Felix, Duncker, Dirk-Jan, Regar, Evelyn, Beusekom, Heleen v

“…Methods Of 15 farm-bred swine, 8 received streptozotocin to induce diabetes mellitus (DM), then a high cholesterol diet was given to all 15 swine…”
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Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine by De Wijs-Meijler, Daphne P M, Stam, Kelly, van Duin, Richard W B, Verzijl, Annemarie, Reiss, Irwin K, Duncker, Dirk J, Merkus, Daphne

“…This protocol describes the surgical procedure to chronically instrument swine and the procedure to exercise swine on a motor-driven treadmill. Early…”
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Intervening with the Nitric Oxide Pathway to Alleviate Pulmonary Hypertension in Pulmonary Vein Stenosis by van Duin, Richard W B, Stam, Kelly, Uitterdijk, André, Bartelds, Beatrijs, Danser, A H Jan, Reiss, Irwin K M, Duncker, Dirk J, Merkus, Daphne

“…Pulmonary hypertension (PH) as a result of pulmonary vein stenosis (PVS) is extremely difficult to treat. The ideal therapy should not target the…”
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Impaired Oxygenation of the Right Ventricle during Development of Pulmonary Hypertension in Swine is not due to Loss of Nitric Oxide by Merkus, Daphne, Steenhorst, Jarno J., van Duin, Richard W., Cai, Zongye, Duncker, Dirk J.

“…Abstract only Background Pulmonary hypertension (PH) increases workload of the right ventricle (RV), resulting in RV hypertrophy. Eventually the RV is unable…”
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Abstract 21287: Myocardial Oxygen Delivery is Progressively Impaired During Development of Pulmonary Hypertension by van Duin, Richard W, Cai, Zongye, Duncker, Dirk J, Merkus, Daphne

“…Abstract only Introduction: Pulmonary hypertension (PH) increases afterload of the right ventricle (RV), initially resulting in RV hypertrophy. Eventually the…”
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