Search Results - "van Duijnhoven, Gerard"
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Marginal zone macrophages express a murine homologue of DC-SIGN that captures blood-borne antigens in vivo
Published in Blood (15-10-2002)“…Antigen-presenting cells are localized in essentially every tissue, where they operate at the interface of innate and acquired immunity by capturing pathogens…”
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Identification of Different Binding Sites in the Dendritic Cell-specific Receptor DC-SIGN for Intercellular Adhesion Molecule 3 and HIV-1
Published in The Journal of biological chemistry (29-03-2002)“…The novel dendritic cell (DC)-specific human immunodeficiency virus type 1 (HIV-1) receptor DC-SIGN plays a key role in the dissemination of HIV-1 by DC…”
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DC-SIGN-ICAM-2 interaction mediates dendritic cell trafficking
Published in Nature immunology (01-10-2000)“…Dendritic cells (DCs) are recruited from blood into tissues to patrol for foreign antigens. After antigen uptake and processing, DCs migrate to the secondary…”
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Identification of DC-SIGN, a Novel Dendritic Cell–Specific ICAM-3 Receptor that Supports Primary Immune Responses
Published in Cell (03-03-2000)“…Contact between dendritic cells (DC) and resting T cells is essential to initiate a primary immune response. Here, we demonstrate that ICAM-3 expressed by…”
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DC-SIGN, a Dendritic Cell–Specific HIV-1-Binding Protein that Enhances trans-Infection of T Cells
Published in Cell (03-03-2000)“…Dendritic cells (DC) capture microorganisms that enter peripheral mucosal tissues and then migrate to secondary lymphoid organs, where they present these in…”
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Positional cloning of the gene for X-linked retinitis pigmentosa 2
Published in Nature genetics (01-08-1998)“…X-linked retinitis pigmentosa (XLRP) results from mutations in at least two different loci, designated RP2 and RP3, located at Xp11.3 and Xp21.1, respectively…”
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A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection
Published in The Journal of experimental medicine (19-03-2001)“…The discovery of dendritic cell (DC)-specific intercellular adhesion molecule (ICAM)-3-grabbing nonintegrin (DC-SIGN) as a DC-specific ICAM-3 binding receptor…”
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A novel mutation identified in the DFNA5 gene in a Dutch family: a clinical and genetic evaluation
Published in Audiology & neurotology (01-01-2004)“…A novel DFNA5 mutation was found in a Dutch family, of which 37 members were examined. A nucleotide substitution was identified in the splice acceptor site of…”
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Rhesus macaque and chimpanzee DC-SIGN act as HIV/SIV gp120 trans-receptors, similar to human DC-SIGN
Published in Immunology letters (01-11-2001)“…Dendritic cells (DC) have been implicated in the pathogenesis of both human and simian immunodeficiency viruses (HIV and SIV, respectively). The DC-specific…”
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Positional Cloning of the Gene for X-Linked Retinitis Pigmentosa 3: Homology with the Guanine-Nucleotide-Exchange Factor RCC1
Published in Human molecular genetics (01-07-1996)“…The gene for retinitis pigmentosa 3 (RP3), the most frequent form of X-linked RP (XLRP), has been mapped previously to a chromosome interval of less than 1000…”
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Audiometric, vestibular, and genetic aspects of a DFNA9 family with a G88E COCH mutation
Published in Otology & neurotology (01-09-2005)“…To perform genetic analysis and to analyze cochleovestibular impairment features in a newly identified Dutch family with nonsyndromic autosomal dominant…”
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12
A Novel Ribosomal S6-Kinase (RSK4; RPS6KA6) Is Commonly Deleted in Patients with Complex X-Linked Mental Retardation
Published in Genomics (San Diego, Calif.) (15-12-1999)“…Large deletions in Xq21 often are associated with contiguous gene syndromes consisting of X-linked deafness type 3 (DFN3), mental retardation (MRX), and…”
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A Single Amino Acid in the Cytoplasmic Domain of the β2 Integrin Lymphocyte Function-associated Antigen-1 Regulates Avidity-dependent Inside-out Signaling
Published in The Journal of biological chemistry (30-03-2001)“…The leukocyte-specific β2integrin lymphocyte function-associated antigen-1 (LFA-1) (αL/β2) mediates activation-dependent adhesion to intercellular adhesion…”
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14
Continuous beta-galactosidase production in insect cells with a p10 gene based baculovirus vector in a two-stage bioreactor system
Published in Biotechnology progress (01-01-1994)“…Continuous production of polyhedra or baculovirus‐expressed proteins in insect cell cultures is limited to about 4 weeks. The decrease in production has been…”
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Identification of a Gene Disrupted by a Microdeletion in a Patient with X-Linked Retinitis Pigmentosa (XLRP)
Published in Human molecular genetics (01-06-1996)“…The gene for the most frequent form of X-linked retinitis pigmentosa (XLRP), RP3, has been assigned by genetic and physical mapping to a segment of less than…”
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Intrafamilial variability of the ocular phenotype in a Polish family with a missense mutation (A63D) in the Norrie disease gene
Published in Ophthalmic genetics (01-09-1998)“…Purpose: To describe the phenotypic variability in a Polish Norrie disease (ND) family associated with the missense mutation A63D. Methods: A patient with…”
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Linkage analysis of a Dutch family with X-linked recessive congenital stationary night blindness (XL-CSNB)
Published in Human genetics (1995)“…Linkage analysis has been performed in a large Dutch pedigree with X-linked recessive congenital stationary night blindness (CSNB) by utilizing 16 DNA markers…”
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A Dutch Family With Hearing Loss Linked to the DFNA20/26 Locus: Longitudinal Analysis of Hearing Impairment
Published in Archives of otolaryngology--head & neck surgery (01-03-2004)“…OBJECTIVES To perform linkage analysis and to outline hearing loss characteristics in a family exhibiting a nonsyndromic, autosomal dominant type of…”
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A Single Amino Acid in the Cytoplasmic Domain of the β2 Integrin Lymphocyte Function-associated Antigen-1 Regulates Avidity-dependent Inside-out Signaling
Published in The Journal of biological chemistry (30-03-2001)“…The leukocyte-specific β 2 integrin lymphocyte function-associated antigen-1 (LFA-1) (α L /β 2 ) mediates activation-dependent adhesion to intercellular…”
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