Search Results - "van Drunen, M"

The Transcription Factor GATA3 Is Essential for the Function of Human Type 2 Innate Lymphoid Cells by Mjösberg, Jenny, Bernink, Jochem, Golebski, Korneliusz, Karrich, Julien J., Peters, Charlotte P., Blom, Bianca, te Velde, Anje A., Fokkens, Wytske J., van Drunen, Cornelis M., Spits, Hergen

“…Type 2 innate lymphoid cells (ILC2s) are part of a large family of ILCs that are important effectors in innate immunity, lymphoid organogenesis, and tissue…”
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IL-1β, IL-23, and TGF-β drive plasticity of human ILC2s towards IL-17-producing ILCs in nasal inflammation by Golebski, Korneliusz, Ros, Xavier R., Nagasawa, Maho, van Tol, Sophie, Heesters, Balthasar A., Aglmous, Hajar, Kradolfer, Chantal M. A., Shikhagaie, Medya M., Seys, Sven, Hellings, P. W., van Drunen, Cornelis M., Fokkens, Wytske J., Spits, Hergen, Bal, Suzanne M.

“…Innate lymphoid cells (ILCs) are crucial for the immune surveillance at mucosal sites. ILCs coordinate early eradication of pathogens and contribute to tissue…”
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Endotyping of non-allergic, allergic and mixed rhinitis patients using a broad panel of biomarkers in nasal secretions by Segboer, Christine L, Fokkens, Wytske J, Terreehorst, Ingrid, van Drunen, Cornelis M

“…Endotyping chronic rhinitis has proven hardest for the subgroup of non-allergic rhinitis (NAR) patients. While IgE-related inflammation is typical for allergic…”
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Childhood asthma in the new omics era: challenges and perspectives by Golebski, Korneliusz, Kabesch, Michael, Melén, Erik, Potočnik, Uroš, van Drunen, Cornelis M., Reinarts, Susanne, Maitland-van der Zee, Anke H., Vijverberg, Susanne J.H.

“…PURPOSE OF REVIEWChildhood asthma is a heterogeneous inflammatory disease comprising different phenotypes and endotypes and, particularly in its severe forms,…”
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Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161 by Mjösberg, Jenny M, Trifari, Sara, Crellin, Natasha K, Peters, Charlotte P, van Drunen, Cornelis M, Piet, Berber, Fokkens, Wytske J, Cupedo, Tom, Spits, Hergen

“…Mice have lineage-negative IL-7Rα + (innate lymphoid) cells that contribute to type 2 immunity. Spits and colleagues identify a similar CRTH2 + CD161 +…”
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Nasal hyper‐reactivity is a common feature in both allergic and nonallergic rhinitis by Segboer, C. L., Holland, C. T., Reinartz, S. M., Terreehorst, I., Gevorgyan, A., Hellings, P. W., Drunen, C. M., Fokkens, W. J.

“…Background Nasal hyper‐reactivity is an increased sensitivity of the nasal mucosa to various nonspecific stimuli. Both allergic rhinitis (AR) and nonallergic…”
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The impact of allergic rhinitis and asthma on human nasal and bronchial epithelial gene expression by Wagener, Ariane H, Zwinderman, Aeilko H, Luiten, Silvia, Fokkens, Wytske J, Bel, Elisabeth H, Sterk, Peter J, van Drunen, Cornelis M

“…The link between upper and lower airways in patients with both asthma and allergic rhinitis is still poorly understood. As the biological complexity of these…”
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How epithelial cells detect danger: aiding the immune response by Vroling, A.B, Fokkens, W.J, van Drunen, C.M

“…The epithelial layer occupies a strategic important location between an organisms' interior and exterior environment. Although as such it forms a physical…”
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The multi‐faceted role of allergen exposure to the local airway mucosa by Golebski, K., Röschmann, K. I. L., Toppila‐Salmi, S., Hammad, H., Lambrecht, B. N., Renkonen, R., Fokkens, W. J., Drunen, C. M.

“…Airway epithelial cells are the first to encounter aeroallergens and therefore have recently become an interesting target of many studies investigating their…”
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Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198 by Molenaar, Remco J, Botman, Dennis, Smits, Myrthe A, Hira, Vashendriya V, van Lith, Sanne A, Stap, Jan, Henneman, Peter, Khurshed, Mohammed, Lenting, Krissie, Mul, Adri N, Dimitrakopoulou, Dionysia, van Drunen, Cornelis M, Hoebe, Ron A, Radivoyevitch, Tomas, Wilmink, Johanna W, Maciejewski, Jaroslaw P, Vandertop, W Peter, Leenders, William P, Bleeker, Fonnet E, van Noorden, Cornelis J

“…Isocitrate dehydrogenase 1 (IDH1) is mutated in various types of human cancer to IDH1(R132H), a structural alteration that leads to catalysis of…”
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Transcriptome changes during peanut oral immunotherapy and omalizumab treatment by Björkander, Sophia, Merid, Simon Kebede, Brodin, David, Brandström, Josef, Fagerström‐Billai, Fredrik, Heiden, Marieke, Konradsen, Jon R., Kabesch, Michael, Drunen, Cornelis M., Golebski, Korneliusz, Maitland‐van der Zee, Anke H., Potočnik, Uroš, Vijverberg, Susanne J. H., Nopp, Anna, Nilsson, Caroline, Melén, Erik, Peters, Rachel

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Endothelial L-selectin ligand expression in nasal polyps by Ebbens, F.A, Toppila-Salmi, S.K, Renkonen, J.A, Renkonen, R.L.O, Mullol, J, van Drunen, C.M, Fokkens, W.J

“…L-selectins on leukocytes and their counter-receptors on endothelial cells have been shown to be involved in leukocyte recruitment in chronic rhinosinusitis…”
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Specific Induction of TSLP by the Viral RNA Analogue Poly(I:C) in Primary Epithelial Cells Derived from Nasal Polyps by Golebski, Korneliusz, van Tongeren, Joost, van Egmond, Danielle, de Groot, Esther J, Fokkens, Wytske J, van Drunen, Cornelis M

“…Chronic rhinosinusitis with nasal polyposis is an inflammatory disease that, although not directly linked to allergy, often displays a Th2-skewed inflammation…”
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Comparison of expression profiles induced by dust mite in airway epithelia reveals a common pathway by Vroling, A.B, Jonker, M.J, Breit, T.M, Fokkens, W.J, Drunen, C.M. van

“…Airway epithelial cells have shown to be active participants in the defense against pathogens by producing signaling and other regulatory molecules in response…”
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SAF-Box, a Conserved Protein Domain That Specifically Recognizes Scaffold Attachment Region DNA by Kipp, Michael, Göhring, Frank, Ostendorp, Thorsten, van Drunen, Cornelis M., van Driel, Roel, Przybylski, Michael, Fackelmayer, Frank O.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Inflammation in Chronic Rhinosinusitis and Nasal Polyposis by van Drunen, Cornelis M., PhD, Reinartz, Susanne, MD, Wigman, Jochem, MD, Fokkens, Wytske J., MD, PhD

“…Inflammation is a defining characteristic of chronic rhinosinusitis and nasal polyposis. Research had traditionally focused on the role of eosinophils in the…”
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Executive summary of European Task Force document on diagnostic tools in rhinology by HELLINGS, P. W, SCADDING, G, MULLOL, J, PASSALACQUA, G, TOSKALA, E, DRUNEN, C. M. Van, ALOBID, I, BACHERT, C, FOKKENS, W. J, GERTH VAN WIJK, R, GEVAERT, P, GUILEMANY, J, KALOGJERA, L, LUND, V. J

“…This Executive Summary of the EAACI Task Force document on Diagnostic Tools in Rhinology provides the readers with an over- view of the currently available…”
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Influence of the gut and airway microbiome on asthma development and disease by Smulders, Tamar, Van Der Schee, Marc P., Maitland‐Van Der Zee, Anke H., Dikkers, Frederik G., Van Drunen, Cornelis M.

“…There are ample data to suggest that early‐life dysbiosis of both the gut and/or airway microbiome can predispose a child to develop along a trajectory toward…”
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Timothy grass pollen extract-induced gene expression and signalling pathways in airway epithelial cells by Röschmann, K I. L., Luiten, S., Jonker, M. J., Breit, T. M., Fokkens, W. J., Petersen, A., van Drunen, C. M.

“…Cite this as: K. I. L. Röschmann, S. Luiten, M. J. Jonker, T. M. Breit, W. J. Fokkens, A. Petersen and C. M. van Drunen, Clinical & Experimental Allergy, 2011…”
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Dendritic Cell Subsets in Oral Mucosa of Allergic and Healthy Subjects by Reinartz, Susanne M, van Tongeren, Joost, van Egmond, Danielle, de Groot, Esther J J, Fokkens, Wytske J, van Drunen, Cornelis M

“…Immunohistochemistry was used to identify, enumerate, and describe the tissue distribution of Langerhans type (CD1a and CD207), myeloid (CD1c and CD141), and…”
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