Search Results - "van Driel, Marc A"

A text-mining analysis of the human phenome by VAN DRIEL, Marc A, BRUGGEMAN, Jorn, VRIEND, Gert, BRUNNER, Han G, LEUNISSEN, Jack A. M

“…A number of large-scale efforts are underway to define the relationships between genes and proteins in various species. But, few attempts have been made to…”
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Characterization of genome-wide p53-binding sites upon stress response by Smeenk, Leonie, van Heeringen, Simon J, Koeppel, Max, van Driel, Marc A, Bartels, Stefanie J.J, Akkers, Robert C, Denissov, Sergei, Stunnenberg, Hendrik G, Lohrum, Marion

“…The tumor suppressor p53 is a sequence-specific transcription factor, which regulates the expression of target genes involved in different stress responses. To…”
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Genome-Wide Pattern of TCF7L2/TCF4 Chromatin Occupancy in Colorectal Cancer Cells by Hatzis, Pantelis, van der Flier, Laurens G., van Driel, Marc A., Guryev, Victor, Nielsen, Fiona, Denissov, Sergei, Nijman, Isaäc J., Koster, Jan, Santo, Evan E., Welboren, Willem, Versteeg, Rogier, Cuppen, Edwin, van de Wetering, Marc, Clevers, Hans, Stunnenberg, Hendrik G.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Dynamic histone H3 epigenome marking during the intraerythrocytic cycle of Plasmodium falciparum by Salcedo-Amaya, Adriana M, van Driel, Marc A, Alako, Blaise T, Trelle, Morten B, van den Elzen, Antonia M.G, Cohen, Adrian M, Janssen-Megens, Eva M, van de Vegte-Bolmer, Marga, Selzer, Rebecca R, Iniguez, A. Leonardo, Green, Roland D, Sauerwein, Robert W, Jensen, Ole N, Stunnenberg, Hendrik G

“…Epigenome profiling has led to the paradigm that promoters of active genes are decorated with H3K4me3 and H3K9ac marks. To explore the epigenome of Plasmodium…”
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MetiTree: a web application to organize and process high-resolution multi-stage mass spectrometry metabolomics data by ROJAS-CHERTO, Miguel, VLIET, Michael Van, PEIRONCELY, Julio E, DOORN, Ronnie Van, KOOYMAN, Maarten, TE BEEK, Tim, DRIEL, Marc A. Van, HANKEMEIER, Thomas, REIJMERS, Theo

“…Identification of metabolites using high-resolution multi-stage mass spectrometry (MS(n)) data is a significant challenge demanding access to all sorts of…”
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ODoSE: a webserver for genome-wide calculation of adaptive divergence in prokaryotes by Vos, Michiel, te Beek, Tim A H, van Driel, Marc A, Huynen, Martijn A, Eyre-Walker, Adam, van Passel, Mark W J

“…Quantifying patterns of adaptive divergence between taxa is a major goal in the comparative and evolutionary study of prokaryote genomes. When applied…”
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ChIP-Seq of ERα and RNA polymerase II defines genes differentially responding to ligands by Welboren, Willem-Jan, van Driel, Marc A, Janssen-Megens, Eva M, van Heeringen, Simon J, Sweep, Fred CGJ, Span, Paul N, Stunnenberg, Hendrik G

“…We used ChIP‐Seq to map ERα‐binding sites and to profile changes in RNA polymerase II (RNAPII) occupancy in MCF‐7 cells in response to estradiol (E2),…”
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Novel types of mutation in the choroideremia (CHM) gene: a full-length L1 insertion and an intronic mutation activating a cryptic exon by VAN DEN HURK, José A. J. M, VAN DE POL, Dorien J. R, ROPERS, Hans-Hilger, CREMERS, Frans P. M, WISSINGER, Bernd, VAN DRIEL, Marc A, HOEFSLOOT, Lies H, DE WIJS, Ilse J, VAN DEN BORN, L. Ingeborgh, HECKENLIVELY, John R, BRUNNER, Han G, ZRENNER, Eberhart

“…Choroideremia (CHM) is a progressive chorioretinal degeneration caused by mutations in the widely expressed CHM gene on chromosome Xq21. The product of this…”
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Bioinformatics methods for identifying candidate disease genes by van Driel, Marc A, Brunner, Han G

“…With the explosion in genomic and functional genomics information, methods for disease gene identification are rapidly evolving. Databases are now essential to…”
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From syndrome families to functional genomics by Brunner, Han G, van Driel, Marc A

“…There are more than 2,000 monogenic syndromes in man. Each syndrome has a specific combination of phenotypic features, and each differs from other syndromes by…”
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Modulating crossover positioning by introducing large structural changes in chromosomes by Ederveen, Antoine, Lai, Yuching, van Driel, Marc A, Gerats, Tom, Peters, Janny L

“…Crossing over assures the correct segregation of the homologous chromosomes to both poles of the dividing meiocyte. This exchange of DNA creates new allelic…”
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Computational disease gene identification: a concert of methods prioritizes type 2 diabetes and obesity candidate genes by Tiffin, Nicki, Adie, Euan, Turner, Frances, Brunner, Han G., van Driel, Marc A., Oti, Martin, Lopez-Bigas, Nuria, Ouzounis, Christos, Perez-Iratxeta, Carolina, Andrade-Navarro, Miguel A., Adeyemo, Adebowale, Patti, Mary Elizabeth, Semple, Colin A. M., Hide, Winston

“…Genome-wide experimental methods to identify disease genes, such as linkage analysis and association studies, generate increasingly large candidate gene sets…”
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iAnn: an event sharing platform for the life sciences by Jimenez, Rafael C, Albar, Juan P, Bhak, Jong, Blatter, Marie-Claude, Blicher, Thomas, Brazas, Michelle D, Brooksbank, Cath, Budd, Aidan, De Las Rivas, Javier, Dreyer, Jacqueline, van Driel, Marc A, Dunn, Michael J, Fernandes, Pedro L, van Gelder, Celia W G, Hermjakob, Henning, Ioannidis, Vassilios, Judge, David P, Kahlem, Pascal, Korpelainen, Eija, Kraus, Hans-Joachim, Loveland, Jane, Mayer, Christine, McDowall, Jennifer, Moran, Federico, Mulder, Nicola, Nyronen, Tommi, Rother, Kristian, Salazar, Gustavo A, Schneider, Reinhard, Via, Allegra, Villaveces, Jose M, Yu, Ping, Schneider, Maria V, Attwood, Teresa K, Corpas, Manuel

“…We present iAnn, an open source community-driven platform for dissemination of life science events, such as courses, conferences and workshops. iAnn allows…”
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A new web-based data mining tool for the identification of candidate genes for human genetic disorders by VAN DRIEL, Marc A, CUELENAERE, Koen, KEMMEREN, Patrick P. C. W, LEUNISSEN, Jack A. M, BRUNNER, Han G

“…To identify the gene underlying a human genetic disorder can be difficult and time-consuming. Typically, positional data delimit a chromosomal region that…”
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Autosomal Dominant Rhegmatogenous Retinal Detachment Associated with an Arg453Ter Mutation in the COL2A1 Gene by Go, Sioe Lie, Maugeri, Alessandra, Mulder, Jef J. S, van Driel, Marc A, Cremers, Frans P. M, Hoyng, Carel B

“…To investigate the clinical features and molecular causes of autosomal dominant rhegmatogenous retinal detachment (RRD) in two large families. Clinical…”
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ABCR unites what ophthalmologists divide(s) by van Driel, Marc A., Maugeri, Alessandra, Klevering, B. Jeroen, Hoyng, Carel B., Cremers, Frans P.M.

“…Over the last years, the molecular causes of monogenic chorioretinal diseases have been elucidated at an increasing pace. In contrast, only recently have…”
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Isolation and Mapping of Novel Candidate Genes for Retinal Disorders Using Suppression Subtractive Hybridization by den Hollander, Anneke I., van Driel, Marc A., de Kok, Yvette J.M., van de Pol, Dorien J.R., Hoyng, Carel B., Brunner, Han G., Deutman, August F., Cremers, Frans P.M.

“…We have constructed human cDNA libraries enriched for retina- and retinal pigment epithelium (RPE)/choroid-specific cDNAs through suppression subtractive…”
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Genomic structure and assessment of the retinally expressed RFamide-related peptide gene in dominant cystoid macular dystrophy by Schulz, Heidi L, Stoehr, Heidi, White, Karen, van Driel, Marc A, Hoyng, Carel B, Cremers, Frans, Weber, Bernhard H F

“…Computer-assisted sampling of EST data contained within the UniGene human sequences collection is being used to establish a catalog of novel genes that are…”
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MetIDB: A Publicly Accessible Database of Predicted and Experimental 1 H NMR Spectra of Flavonoids by Mihaleva, Velitchka V., te Beek, Tim A. H., van Zimmeren, Frank, Moco, Sofia, Laatikainen, Reino, Niemitz, Matthias, Korhonen, S.-P., van Driel, Marc A., Vervoort, Jacques

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Mutations in a human homologue of Drosophila crumbs cause retinitis pigmentosa (RP12) by Cremers, Frans P.M, den Hollander, Anneke I, ten Brink, Jacoline B, de Kok, Yvette J.M, van Soest, Simone, van den Born, L. Ingeborgh, van Driel, Marc A, van de Pol, Dorien J.R, Payne, Annette M, Bhattacharya, Shomi S, Kellner, Ulrich, Hoyng, Carel B, Westerveld, Andries, Brunner, Han G, Bleeker-Wagemakers, Elisabeth M, Deutman, August F, Heckenlively, John R, Bergen, Arthur A.B

“…Retinitis pigmentosa (RP) comprises a clinically and genetically heterogeneous group of diseases that afflicts approximately 1.5 million people worldwide…”
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