Search Results - "van Doorn, Martijn B A"
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Treatment with the Topical Antimicrobial Peptide Omiganan in Mild-to-Moderate Facial Seborrheic Dermatitis versus Ketoconazole and Placebo: Results of a Randomized Controlled Proof-of-Concept Trial
Published in International journal of molecular sciences (01-09-2023)“…Facial seborrheic dermatitis (SD) is an inflammatory skin disease characterized by erythematous and scaly lesions on the skin with high sebaceous gland…”
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Lesional Psoriasis is Associated With Alterations in the Stratum Corneum Ceramide Profile and Concomitant Decreases in Barrier Function
Published in Experimental dermatology (01-10-2024)“…ABSTRACT Psoriasis is an inflammatory skin disease associated with an impaired skin barrier. The skin barrier function is dependent on the extracellular lipid…”
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A multimodal, comprehensive characterization of a cutaneous wound model in healthy volunteers
Published in Experimental dermatology (01-07-2023)“…Development of pharmacological interventions for wound treatment is challenging due to both poorly understood wound healing mechanisms and heterogeneous…”
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4
Effect of garlic powder on C-reactive protein and plasma lipids in overweight and smoking subjects
Published in The American journal of clinical nutrition (01-12-2006)“…BACKGROUND: Epidemiologic studies suggest that garlic may have beneficial effects on risk factors associated with cardiovascular disease (CVD). However, these…”
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Bleomycin administered by laser-assisted drug delivery or intradermal needle-injection results in distinct biodistribution patterns in skin: in vivo investigations with mass spectrometry imaging
Published in Drug delivery (01-01-2021)“…Bleomycin (BLM) is being repositioned in dermato-oncology for intralesional and intra-tumoural use. Although conventionally administered by local needle…”
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Complement Activation in Inflammatory Skin Diseases
Published in Frontiers in immunology (16-04-2018)“…The complement system is a fundamental part of the innate immune system, playing a crucial role in host defense against various pathogens, such as bacteria,…”
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Needle‐free jet injection‐induced small‐droplet aerosol formation during intralesional bleomycin therapy
Published in Lasers in surgery and medicine (01-04-2022)“…Objectives Needle‐free jet injectors are frequently used in dermatological practice. Injection‐generated small‐droplet aerosols could be harmful upon…”
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Needle-free electronically controlled jet injection with corticosteroids in recalcitrant keloid scars: a retrospective study and patient survey
Published in Lasers in medical science (02-11-2023)“…First-line treatment of keloids consists of intralesional needle injections with corticosteroids, but generally entails multiple painful sessions, resulting in…”
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Clinical endpoints of needle‐free jet injector treatment: An in depth understanding of immediate skin responses
Published in Lasers in surgery and medicine (01-07-2022)“…Objectives Needle‐free jet injectors have been used in dermatological practice for many years. However, predefined clinical endpoints that guide physicians to…”
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10
Electronic Pneumatic Injection‐Assisted Dermal Drug Delivery Visualized by Ex Vivo Confocal Microscopy
Published in Lasers in surgery and medicine (01-01-2021)“…Background and Objectives Electronic pneumatic injection (EPI) is a technique for dermal drug delivery, which is increasingly being used in clinical practice…”
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Lesional skin of seborrheic dermatitis patients is characterized by skin barrier dysfunction and correlating alterations in the stratum corneum ceramide composition
Published in Experimental dermatology (01-01-2024)“…Seborrheic dermatitis (SD) is a chronic inflammatory skin disease characterized by erythematous papulosquamous lesions in sebum rich areas such as the face and…”
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Complement Activation in Autoimmune Bullous Dermatoses: A Comprehensive Review
Published in Frontiers in immunology (26-06-2019)“…Autoimmune bullous dermatoses (AIBD) are characterized by circulating autoantibodies that are either directed against epidermal antigens or deposited as immune…”
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Hypoglycaemia following JAK inhibitor treatment in patients with diabetes
Published in Annals of the rheumatic diseases (01-04-2022)Get more information
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14
The biodistribution of triamcinolone acetonide injections in severe keloids: an exploratory three-dimensional fluorescent cryomicrotome study
Published in Archives of Dermatological Research (08-06-2024)“…Intralesional corticosteroid injections are a first-line treatment for keloids; yet clinical treatment results are highly variable and often suboptimal…”
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Successful pharmacological intervention at different levels of the complement system in an in vitro complement fixation model for bullous pemphigoid
Published in Experimental dermatology (01-05-2023)“…Bullous pemphigoid (BP) is characterized by deposition of immunoglobulins and complement along the epidermal basement membrane (BM). In humans, there is a lack…”
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16
Oral prednisolone suppresses skin inflammation in a healthy volunteer imiquimod challenge model
Published in Frontiers in immunology (20-07-2023)“…Imiquimod (IMQ) is a topical agent that induces local inflammation the Toll-like receptor 7 pathway. Recently, an IMQ-driven skin inflammation model was…”
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Histopathological characteristics are instrumental to distinguish monomorphic from polymorphic maculopapular cutaneous mastocytosis in children
Published in Clinical and experimental dermatology (01-09-2022)“…Background Mastocytosis is characterized by the accumulation of mast cells (MCs) in the skin or other organs, and can manifest at any age. A significant number…”
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Is methotrexate safe for men with an immune-mediated inflammatory disease and an active desire to become a father? Results of a prospective cohort study (iFAME-MTX)
Published in Annals of the rheumatic diseases (01-08-2023)“…Current scientific evidence guiding the decision whether men with an active desire to become a father should be treated with methotrexate (MTX) remains…”
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Comparison of Three Assays to Quantify Infliximab, Adalimumab, and Etanercept Serum Concentrations
Published in Therapeutic drug monitoring (01-08-2016)“…To optimize treatment of inflammatory diseases, interest in the measurement of anti-tumor necrosis factor alpha (anti-TNFα) serum drug concentrations is…”
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Effectiveness and tolerability of personalized omalizumab treatment in patients with chronic inducible urticaria
Published in The journal of allergy and clinical immunology in practice (Cambridge, MA) (01-08-2021)“…[...]published evidence of omalizumab in CIndU is limited to small case series and randomized controlled trials evaluating the standard dosing regimen (300…”
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