Search Results - "van Dijk, Karin D"

Salivation in Parkinson's disease: A scoping review by Verhoeff, Merel C., Koutris, Michail, Vries, Ralph de, Berendse, Henk W., Dijk, Karin D. van, Lobbezoo, Frank

“…Objectives We aimed to provide an overview of the available literature that includes both objective assessments (namely hypersalivation and hyposalivation) and…”
Get full text

Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson's disease by Majbour, Nour K, Vaikath, Nishant N, van Dijk, Karin D, Ardah, Mustafa T, Varghese, Shiji, Vesterager, Louise B, Montezinho, Liliana P, Poole, Stephen, Safieh-Garabedian, Bared, Tokuda, Takahiko, Teunissen, Charlotte E, Berendse, Henk W, van de Berg, Wilma D J, El-Agnaf, Omar M A

“…Despite decades of intensive research, to date, there is no accepted diagnosis for Parkinson's disease (PD) based on biochemical analysis of blood or CSF…”
Get full text

Parkinson’s disease, temporomandibular disorder pain and bruxism and its clinical consequences: a protocol of a single-centre observational outpatient study by Verhoeff, Merel Charlotte, Koutris, Michail, Berendse, Henk W, van Dijk, Karin D, Lobbezoo, F

“…IntroductionA recent questionnaire-based study suggested that bruxism and painful temporomandibular disorders (TMD pain) may be more prevalent in patients with…”
Get full text

Deletions at 22q11.2 in idiopathic Parkinson's disease: a combined analysis of genome-wide association data by Mok, Kin Y, FRCP, Sheerin, Una, MRCP, Simón-Sánchez, Javier, PhD, Salaka, Afnan, PhD, Chester, Lucy, MPharm, Escott-Price, Valentina, PhD, Mantripragada, Kiran, PhD, Doherty, Karen M, MD, Noyce, Alastair J, MRCP, Mencacci, Niccolo E, MD, Lubbe, Steven J, PhD, Williams-Gray, Caroline H, PhD, Barker, Roger A, Prof, van Dijk, Karin D, MD, Berendse, Henk W, Prof, Heutink, Peter, Prof, Corvol, Jean-Christophe, Prof, Cormier, Florence, MD, Lesage, Suzanne, PhD, Brice, Alexis, Prof, Brockmann, Kathrin, MD, Schulte, Claudia, PhD, Gasser, Thomas, Prof, Foltynie, Thomas, PhD, Limousin, Patricia, Prof, Morrison, Karen E, Prof, Clarke, Carl E, Prof, Sawcer, Stephen, Prof, Warner, Tom T, Prof, Lees, Andrew J, Prof, Morris, Huw R, Prof, Nalls, Mike A, PhD, Singleton, Andrew B, PhD, Hardy, John, Prof, Abramov, Andrey Y, Prof, Plagnol, Vincent, PhD, Williams, Nigel M, Dr, Wood, Nicholas W, Prof

“…Summary Background Parkinson's disease has been reported in a small number of patients with chromosome 22q11.2 deletion syndrome. In this study, we screened a…”
Get full text

Inflammatory Blood Biomarkers Are Associated with Long-Term Clinical Disease Severity in Parkinson's Disease by Hepp, Dagmar H, van Wageningen, Thecla A, Kuiper, Kirsten L, van Dijk, Karin D, Oosterveld, Linda P, Berendse, Henk W, van de Berg, Wilma D J

“…An altered immune response has been identified as a pathophysiological factor in Parkinson's disease (PD). We aimed to identify blood immunity-associated…”
Get full text

Genome-wide association study confirms extant PD risk loci among the Dutch by SIMON-SANCHEZ, Javier, VAN HILTEN, Jacobus J, BLOEM, Bas, VAN DIJK, Karin D, RIVADENEIRA, Fernando, HOFMAN, Albert, UITTERLINDEN, André G, RIZZU, Patrizia, BOCHDANOVITS, Zoltan, SINGLETON, Andrew B, HEUTINK, Peter, VAN DE WARRENBURG, Bart, POST, Bart, BERENDSE, Henk W, AREPALLI, Sampath, HERNANDEZ, Dena G, DE BIE, Rob Ma, VELSEBOER, Daan, SCHEFFER, Hans

“…In view of the population-specific heterogeneity in reported genetic risk factors for Parkinson's disease (PD), we conducted a genome-wide association study…”
Get full text

Clinicians’ view on the management of oral health in Parkinson’s disease patients: a qualitative study by Verhoeff, Merel C., Thymi, Magdalini, Brandwijk, Arnoud N., Heres, Mark S., Koutris, Michail, Berendse, Henk W., van Dijk, Karin D., Lobbezoo, Frank

“…Background due to numerous motor and non-motor symptoms, dental treatment in patients with Parkinson’s Disease (PD) can be challenging. Knowledge regarding…”
Get full text

Diagnostic cerebrospinal fluid biomarkers for Parkinson's disease: A pathogenetically based approach by van Dijk, Karin D, Teunissen, Charlotte E, Drukarch, Benjamin, Jimenez, Connie R, Groenewegen, Henk J, Berendse, Henk W, van de Berg, Wilma D.J

“…Abstract The inaccuracy of the early diagnosis of Parkinson's disease (PD) has been a major incentive for studies aimed at the identification of biomarkers…”
Get full text

Cerebrospinal fluid and plasma clusterin levels in Parkinson's disease by van Dijk, Karin D, Jongbloed, Wesley, Heijst, Johannes A, Teunissen, Charlotte E, Groenewegen, Henk J, Berendse, Henk W, van de Berg, Wilma D.J, Veerhuis, Robert

“…Abstract Clusterin is a multifunctional chaperone protein that has repeatedly been linked to Alzheimer's disease (AD) pathogenesis and, more recently, also to…”
Get full text

Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease by Beilina, Alexandria, Rudenko, Iakov N., Kaganovich, Alice, Civiero, Laura, Chau, Hien, Kalia, Suneil K., Kalia, Lorraine V., Lobbestael, Evy, Chia, Ruth, Ndukwe, Kelechi, Ding, Jinhui, Nalls, Mike A., Olszewski, Maciej, Hauser, David N., Kumaran, Ravindran, Lozano, Andres M., Baekelandt, Veerle, Greene, Lois E., Taymans, Jean-Marc, Greggio, Elisa, Cookson, Mark R.

“…Mutations in leucine-rich repeat kinase 2 (LRRK2) cause inherited Parkinson disease (PD), and common variants around LRRK2 are a risk factor for sporadic PD…”
Get full text

Parkinson's disease and oral health: A systematic review by Verhoeff, Merel C., Eikenboom, Denise, Koutris, Michail, de Vries, Ralph, Berendse, Henk W., van Dijk, Karin D., Lobbezoo, Frank

“…in patients with Parkinson's Disease (PD), oral health can be affected by motor and non-motor symptoms and/or medication use. Therefore, the aim was to…”
Get full text

Orofacial pain and dysfunction in patients with Parkinson's disease: A scoping review by Verhoeff, Merel C., Koutris, Michail, Tambach, Sharine, Eikenboom, Denise, Vries, Ralph, Berendse, Henk W., Dijk, Karin D., Lobbezoo, Frank

“…Background Parkinson's disease (PD) is commonly known as a disorder that affects the smooth performance of body movements. In addition to the motor…”
Get full text

The therapeutic potential of opioids in narcolepsy type 1: A systematic literature review and questionnaire study by Gool, Jari K., van Heese, Eva M., Schinkelshoek, Mink S., Remmerswaal, Aniek, Lammers, Gert Jan, van Dijk, Karin D., Fronczek, Rolf

“…Narcolepsy type 1 is a primary sleep disorder caused by deficient hypocretin transmission leading to excessive daytime sleepiness and cataplexy. Opioids have…”
Get full text

Changes in endolysosomal enzyme activities in cerebrospinal fluid of patients with Parkinson's disease by van Dijk, Karin D., Persichetti, Emanuele, Chiasserini, Davide, Eusebi, Paolo, Beccari, Tommaso, Calabresi, Paolo, Berendse, Henk W., Parnetti, Lucilla, van de Berg, Wilma D. J.

“…ABSTRACT Parkinson's disease (PD) is characterized neuropathologically by the cytoplasmic accumulation of misfolded α‐synuclein in specific brain regions. The…”
Get full text

Clusterin Levels in Plasma Predict Cognitive Decline and Progression to Alzheimer's Disease by Jongbloed, Wesley, van Dijk, Karin D, Mulder, Sandra D, van de Berg, Wilma D J, Blankenstein, Marinus A, van der Flier, Wiesje, Veerhuis, Robert

“…Increased clusterin levels have been reported in brain, cerebrospinal fluid (CSF), and plasma of Alzheimer's disease (AD) patients. Because changes are also…”
Get more information

CSF Biomarkers Reflecting Protein Pathology and Axonal Degeneration Are Associated with Memory, Attentional, and Executive Functioning in Early-Stage Parkinson′s Disease by Oosterveld, Linda P., Kuiper, Tessa I., Majbour, Nour K., Verberk, Inge M. W., van Dijk, Karin D., Twisk, Jos W. R., El-Agnaf, Omar M., Teunissen, Charlotte E., Weinstein, Henry C., Klein, Martin, Berendse, Henk W., van de Berg, Wilma D. J.

“…In early-stage Parkinson′s disease (PD), cognitive impairment is common, and a variety of cognitive domains including memory, attention, and executive…”
Get full text

Is Disturbed Intracortical Excitability a Stable Trait of Chronic Insomnia? A Study Using Transcranial Magnetic Stimulation Before and After Multimodal Sleep Therapy by van der Werf, Ysbrand D, Altena, Ellemarije, van Dijk, Karin D, Strijers, Rob L.M, De Rijke, Wim, Stam, Cornelis J, van Someren, Eus J.W

“…Background Chronic insomnia is a poorly understood disorder. Risk factors for developing chronic insomnia are largely unknown, yet disturbances in brain…”
Get full text

CSF α-synuclein does not discriminate dementia with Lewy bodies from Alzheimer's disease by Reesink, Fransje E, Lemstra, Afina W, van Dijk, Karin D, Berendse, Henk W, van de Berg, Wilma D J, Klein, Martin, Blankenstein, Marinus A, Scheltens, Philip, Verbeek, Marcel M, van der Flier, Wiesje M

“…In this study, we assessed whether cerebrospinal fluid (CSF) levels of the biomarker α-synuclein have a diagnostic value in differential diagnosis of dementia…”
Get more information

The Proteome of the Locus Ceruleus in Parkinson's Disease: Relevance to Pathogenesis by van Dijk, Karin D., Berendse, Henk W., Drukarch, Benjamin, Fratantoni, Silvina A., Pham, Thang V., Piersma, Sander R., Huisman, Evelien, Brevé, John J.P., Groenewegen, Henk J., Jimenez, Connie R., van de Berg, Wilma D.J.

“…The locus ceruleus is among the earliest affected brain regions in Parkinson's disease (PD) showing Lewy body pathology and neuronal loss. To improve our…”
Get full text

Depressive symptoms in Parkinson's disease are related to reduced [123I]FP-CIT binding in the caudate nucleus by Vriend, Chris, Raijmakers, Pieter, Veltman, Dick J, van Dijk, Karin D, van der Werf, Ysbrand D, Foncke, Elisabeth M J, Smit, Jan H, Berendse, Henk W, van den Heuvel, Odile A

“…Background Depression is a common neuropsychiatric symptom in Parkinson's disease (PD). In previous research, PD-related depression was associated with…”
Get full text