Search Results - "van Deventer, Sander J.H."
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Induction of Ovalbumin-Specific Tolerance by Oral Administration of Lactococcus lactis Secreting Ovalbumin
Published in Gastroenterology (New York, N.Y. 1943) (01-08-2007)“…Background & Aims: Obtaining antigen-specific immune suppression is an important goal in developing treatments of autoimmune, inflammatory, and allergic…”
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Bone morphogenetic protein signaling suppresses tumorigenesis at gastric epithelial transition zones in mice
Published in Cancer research (Chicago, Ill.) (01-09-2007)“…Bone morphogenetic protein (BMP) signaling is known to suppress oncogenesis in the small and large intestine of mice and humans. We examined the role of Bmpr1a…”
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3
Adenosine triphosphate-binding cassette transporter genes up-regulation in untreated hepatocellular carcinoma is mediated by cellular microRNAs
Published in Hepatology (Baltimore, Md.) (01-03-2012)“…Adenosine triphosphate (ATP)‐binding cassette (ABC) transporters are drug efflux pumps responsible for the multidrug resistance phenotype causing…”
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Infliximab but not etanercept induces apoptosis in lamina propria T-lymphocytes from patients with Crohn’s disease
Published in Gastroenterology (New York, N.Y. 1943) (01-06-2003)“…Steroid-refractory Crohn’s disease responds to therapy with the chimeric anti-tumor necrosis factor (TNF)-α antibody infliximab. Etanercept, a recombinant TNF…”
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Modulation of cytokine release and neutrophil function by granulocyte colony-stimulating factor during endotoxemia in humans
Published in Blood (15-08-1997)“…In this double-blind, cross-over, placebo-controlled, randomized study, two groups of eight healthy male volunteers were challenged with endotoxin (4 ng/kg) on…”
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Activation of Coagulation after Administration of Tumor Necrosis Factor to Normal Subjects
Published in The New England journal of medicine (07-06-1990)“…Tumor necrosis factor has been implicated in the activation of blood coagulation in septicemia, a condition commonly associated with intravascular coagulation…”
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Endoscopy in inflammatory bowel diseases
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2004)“…A correct diagnosis, adequate assessment of disease activity, avoidance of surgery by endoscopic interventions, and effective cancer surveillance make…”
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Comparative analysis of colonic gene expression of three experimental colitis models mimicking inflammatory bowel disease
Published in Inflammatory bowel diseases (01-03-2007)“…Background: Mouse models of inflammatory bowel diseases (IBD) are used to unravel the pathophysiology of IBD and to study new treatment modalities, but their…”
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Infliximab for the Treatment of Fistulas in Patients with Crohn's Disease
Published in The New England journal of medicine (06-05-1999)“…Crohn's disease is a chronic inflammatory bowel disease of unknown cause, which is characterized by segmental transmural inflammation and granulomatous lesions…”
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10
Bone morphogenetic protein 2 is expressed by, and acts upon, mature epithelial cells in the colon
Published in Gastroenterology (New York, N.Y. 1943) (01-01-2004)“…The recent findings of bone morphogenetic protein (BMP) receptor Ia mutations in juvenile polyposis and frequent Smad4 mutations in colon cancer suggest a role…”
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A Short-Term Study of Chimeric Monoclonal Antibody cA2 to Tumor Necrosis Factor α for Crohn's Disease
Published in The New England journal of medicine (09-10-1997)“…Crohn's disease is a chronic inflammatory disorder characterized by patchy granulomatous inflammation of any part of the gastrointestinal tract. 1 Patients…”
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12
Leptin Is a Growth Factor for Colonic Epithelial Cells
Published in Gastroenterology (New York, N.Y. 1943) (01-07-2001)“…Background & Aims: Obesity increases the risk of colon cancer, whereas physical activity reduces the risk. Plasma levels of leptin increase in proportion to…”
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13
Endoscopic treatment of high-grade dysplasia and early stage cancer in Barrett's esophagus
Published in Gastrointestinal endoscopy (01-04-2005)“…The aim of this study was to prospectively evaluate endoscopic resection (ER) combined with photodynamic therapy (PDT) for the treatment of selected patients…”
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14
Effects of the cholesteryl ester transfer protein inhibitor, TA-8995, on cholesterol efflux capacity and high-density lipoprotein particle subclasses
Published in Journal of clinical lipidology (01-09-2016)“…Background TA-8995 is a potent inhibitor of cholesteryl ester transfer protein (CETP) with beneficial effects on lipids and lipoproteins. The effect of TA-8995…”
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15
Alterations in lipoprotein homeostasis during human experimental endotoxemia and clinical sepsis
Published in Biochimica et biophysica acta (01-12-2007)“…Cell wall constituents of bacteria are potent endotoxins initiating inflammatory responses which may cause dramatic changes in lipid metabolism during the…”
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Safety and efficacy of recombinant human interleukin 10 in chronic active Crohn's disease
Published in Gastroenterology (New York, N.Y. 1943) (01-12-2000)“…Background & Aims: Interleukin (IL)-10 is a cytokine with potent anti-inflammatory properties. We investigated the safety and efficacy of different doses of…”
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Elevated Lipoprotein(a) in Perinatally HIV-Infected Children Compared With Healthy Ethnicity-Matched Controls
Published in Open forum infectious diseases (01-09-2019)“…HIV-associated cardiovascular disease (CVD) risk in combination antiretroviral therapy (cART)-treated perinatally HIV-infected patients (PHIV+) remains unknown…”
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Cytokines and anticytokines in the pathogenesis of sepsis
Published in Infectious disease clinics of North America (01-06-1999)“…Clinical trials with anti-inflammatory agents in patients with sepsis are based on the assumption that excessive proinflammatory activity of the cytokine…”
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A Comparative Analysis by SAGE of Gene Expression Profiles of Barrett’s Esophagus, Normal Squamous Esophagus, and Gastric Cardia
Published in Gastroenterology (New York, N.Y. 1943) (01-10-2005)“…Background & Aims: The metaplastic process in which the normal squamous epithelium of the distal esophagus is replaced by columnar-lined epithelium, known as…”
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Arginine deficiency affects early B cell maturation and lymphoid organ development in transgenic mice
Published in The Journal of clinical investigation (01-11-2002)“…Apart from its role in the synthesis of protein and nitric oxide (NO), and in ammonia detoxification, the amino acid arginine exerts an immunosupportive…”
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