Search Results - "van Delft, Pieter"

Mapping and elucidating the function of modified bases in DNA by Raiber, Eun-Ang, Hardisty, Robyn, van Delft, Pieter, Balasubramanian, Shankar

“…Chemically modified bases exist naturally in genomic DNA. Research into these bases has been invigorated by the discovery of several modified bases in the…”
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The Profile and Dynamics of RNA Modifications in Animals by van Delft, Pieter, Akay, Alper, Huber, Sabrina M., Bueschl, Christoph, Rudolph, Konrad L. M., Di Domenico, Tomás, Schuhmacher, Rainer, Miska, Eric A., Balasubramanian, Shankar

“…More than a hundred distinct modified nucleosides have been identified in RNA, but little is known about their distribution across different organisms, their…”
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Enhanced Methylation Analysis by Recovery of Unsequenceable Fragments by McInroy, Gordon R, Beraldi, Dario, Raiber, Eun-Ang, Modrzynska, Katarzyna, van Delft, Pieter, Billker, Oliver, Balasubramanian, Shankar

“…Bisulfite sequencing is a valuable tool for mapping the position of 5-methylcytosine in the genome at single base resolution. However, the associated chemical…”
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Sequencing abasic sites in DNA at single-nucleotide resolution by Liu, Zheng J., Martínez Cuesta, Sergio, van Delft, Pieter, Balasubramanian, Shankar

“…In DNA, the loss of a nucleobase by hydrolysis generates an abasic site. Formed as a result of DNA damage, as well as a key intermediate during the base…”
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Fully automated sequential solid phase approach towards viral RNA-nucleopeptides by van der Heden van Noort, Gerbrand J, van Delft, Pieter, Meeuwenoord, Nico J, Overkleeft, Herman S, van der Marel, Gijsbert A, Filippov, Dmitri V

“…The synthesis of two ribonucleoprotein fragments of unprecedented complexity is reported. These hybrid biomolecules are prepared combining the use of an…”
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Genome-wide mapping of 5-hydroxymethyluracil in the eukaryote parasite Leishmania by Kawasaki, Fumiko, Beraldi, Dario, Hardisty, Robyn E, McInroy, Gordon R, van Delft, Pieter, Balasubramanian, Shankar

“…5-Hydroxymethyluracil (5hmU) is a thymine base modification found in the genomes of a diverse range of organisms. To explore the functional importance of 5hmU,…”
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Formation and Abundance of 5-Hydroxymethylcytosine in RNA by Huber, Sabrina M., van Delft, Pieter, Mendil, Lee, Bachman, Martin, Smollett, Katherine, Werner, Finn, Miska, Eric A., Balasubramanian, Shankar

“…RNA methylation is emerging as a regulatory RNA modification that could have important roles in the control and coordination of gene transcription and protein…”
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An Epigenetics-Inspired DNA-Based Data Storage System by Mayer, Clemens, McInroy, Gordon R., Murat, Pierre, Van Delft, Pieter, Balasubramanian, Shankar

“…Biopolymers are an attractive alternative to store and circulate information. DNA, for example, combines remarkable longevity with high data storage densities…”
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Furanosyl Oxocarbenium Ion Stability and Stereoselectivity by van Rijssel, Erwin R., van Delft, Pieter, Lodder, Gerrit, Overkleeft, Herman S., van der Marel, Gijsbert A., Filippov, Dmitri V., Codée, Jeroen D. C.

“…Lewis acid mediated substitution reactions using [D]triethylsilane as a nucleophile at the anomeric center of the four pentofuranoses, ribose, arabinose,…”
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Synthesis of Oligoribonucleic Acid Conjugates Using a Cyclooctyne Phosphoramidite by van Delft, Pieter, Meeuwenoord, Nico J, Hoogendoorn, Sascha, Dinkelaar, Jasper, Overkleeft, Herman S, van der Marel, Gijsbert A, Filippov, Dmitri V

“…The conjugation of a ribonucleic acid 16-mer with the cationic amphiphilic peptide penetratin and an anionic hyaluronan tetrasaccharide by means of Cu-free…”
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Erratum: Mapping and elucidating the function of modified bases in DNA by Raiber, Eun-Ang, Hardisty, Robyn, van Delft, Pieter, Balasubramanian, Shankar

“…Nature Reviews Chemistry 1, 0069 (2017) In figure 2 of this article, an incorrect structure for 5-formyluracil was published in the online version, and a…”
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Synthesis of Sugar Nucleotides by Application of Phosphoramidites by Gold, Henrik, van Delft, Pieter, Meeuwenoord, Nico, Codée, Jeroen D. C, Filippov, Dmitri V, Eggink, Gerrit, Overkleeft, Herman S, van der Marel, Gijs A

“…A new method for the construction of pyrophosphates is reported based on the coupling of a sugar phosphate and a nucleoside phosphoramidite. The in situ formed…”
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A Technique for Simulating the Effect of Dose Reduction on Image Quality in Digital Chest Radiography by Veldkamp, Wouter J.H., Kroft, Lucia J.M., van Delft, Jan Pieter A., Geleijns, Jacob

“…Purpose: The purpose of this study is to provide a pragmatic tool for studying the relationship between dose and image quality in clinical chest images. To…”
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Functionality-type and chemical-composition separation of poly(lactide-co-glycolide) using gradient elution normal-phase liquid chromatography with basic and acidic additives by Serizawa, Masashi, Reekers, Jeroen, van Delft, Pieter, van Bruijnsvoort, Michel, Schoenmakers, Peter J., Gargano, Andrea F.G.

“…•A gradient NPLC method using basic and acid additives separates cyclic and acid-terminated PLGAs.•The method was optimized to reduce the molecular weight…”
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2′‑O‑Methyl-5-hydroxymethylcytidine: A Second Oxidative Derivative of 5‑Methylcytidine in RNA by Huber, Sabrina M, van Delft, Pieter, Tanpure, Arun, Miska, Eric A, Balasubramanian, Shankar

“…5-Hydroxymethylcytidine (hm5C) was recently identified as a direct metabolite of m5C in RNA. We investigated the stability of hm5C in human cells using…”
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Detection of simulated nodules on clinical radiographs: dose reduction at digital posteroanterior chest radiography by Kroft, Lucia J M, Veldkamp, Wouter J H, Mertens, Bart J A, van Delft, Jan Pieter A, Geleijns, Jacob

“…To determine to what extent dose reduction results in decreased detection of simulated nodules on patient digital posteroanterior (PA) chest radiographs. Raw…”
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Stereoselectivity in the Lewis Acid Mediated Reduction of Ketofuranoses by van Rijssel, Erwin R, van Delft, Pieter, van Marle, Daan V, Bijvoets, Stefan M, Lodder, Gerrit, Overkleeft, Herman S, van der Marel, Gijsbert A, Filippov, Dmitri V, Codée, Jeroen D. C

“…The Lewis acid mediated reduction of ribose-, arabinose-, xylose-, and lyxose-derived methyl and phenyl ketofuranoses with triethylsilane as nucleophile was…”
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Design of a Ribosyltriazole-Annulated Cyclooctyne for Oligonucleotide Labeling by Strain-Promoted Alkyne-Azide Cycloaddition by van Delft, Pieter, de Witte, Wilbert, Meeuwenoord, Nico J., van der Heden van Noort, Gerbrand J., Versluis, Frank, Olsthoorn, Rene C. L., Overkleeft, Herman S., van der Marel, Gijs A., Filippov, Dmitri V.

“…A ribosyltriazole ring‐fused cyclooctyne was prepared and converted into the corresponding phosphoramidite, which was applied in the automated synthesis of DNA…”
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An Epigenetics-Inspired DNA-Based Data Storage System by Mayer, Clemens, McInroy, Gordon R., Murat, Pierre, Van Delft, Pieter, Balasubramanian, Shankar

“…Biopolymers are an attractive alternative to store and circulate information. DNA, for example, combines remarkable longevity with high data storage densities…”
Get full text

Furanosyl Oxocarbenium Ion Stability and Stereoselectivity by van Rijssel, Erwin R., van Delft, Pieter, Lodder, Gerrit, Overkleeft, Herman S., van der Marel, Gijsbert A., Filippov, Dmitri V., Codée, Jeroen D. C.

“…Lewis acid mediated substitution reactions using [D]triethylsilane as a nucleophile at the anomeric center of the four pentofuranoses, ribose, arabinose,…”
Get full text