Search Results - "van Caam, A.P.M."

Osteoarthritis year in review 2016: biology by Blaney Davidson, E.N, van Caam, A.P.M, van der Kraan, P.M

“…Summary This review highlights a selection of literature in the area of osteoarthritis biology published between the 2015 and 2016 Osteoarthritis Research…”
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TGF-β is a potent inducer of Nerve Growth Factor in articular cartilage via the ALK5-Smad2/3 pathway. Potential role in OA related pain? by Blaney Davidson, E.N, van Caam, A.P.M, Vitters, E.L, Bennink, M.B, Thijssen, E, van den Berg, W.B, Koenders, M.I, van Lent, P.L.E.M, van de Loo, F.A.J, van der Kraan, P.M

“…Summary Objective Pain is the main problem for patients with osteoarthritis (OA). Pain is linked to inflammation, but in OA a subset of patients suffers from…”
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Increased IL-6 receptor expression and signaling in ageing cartilage can be explained by loss of TGF-β-mediated IL-6 receptor suppression by Wiegertjes, R., Thielen, N.G.M., van Caam, A.P.M., van Laar, M., van Beuningen, H.M., Koenders, M.I., van Lent, P.L.E.M., van der Kraan, P.M., van de Loo, F.A.J., Blaney Davidson, E.N.

“…Osteoarthritis (OA) development is strongly associated with ageing, possibly due to age-related changes in transforming growth factor-β (TGF-β) signaling in…”
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IL-37 diminishes proteoglycan loss in human OA cartilage: donor-specific link between IL-37 and MMP-3 by van Geffen, E.W., van Caam, A.P.M., Schreurs, W., van de Loo, F.A., van Lent, P.L.E.M., Koenders, M.I., Thudium, C.S., Bay-Jensen, A.C., Blaney Davidson, E.N., van der Kraan, P.M.

“…A hallmark of osteoarthritis (OA) is degradation of articular cartilage proteoglycans. In isolated human OA chondrocytes, the anti-inflammatory cytokine…”
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