Search Results - "van Bochove, Gregor G. W."
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Non-Invasive Imaging and Scoring of Peritoneal Metastases in Small Preclinical Animal Models Using Ultrasound: A Preliminary Trial
Published in Biomedicines (06-07-2022)“…Background: The peritoneum is a common site for the formation of metastases originating from several gastrointestinal and gynecological malignancies. A…”
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Dual TORK/DNA-PK inhibition blocks critical signaling pathways in chronic lymphocytic leukemia
Published in Blood (28-07-2016)“…Inhibition of B-cell receptor (BCR) signaling pathways in chronic lymphocytic leukemia (CLL) provides significant clinical benefit to patients, mainly by…”
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PARP1-Inhibition Sensitizes Cervical Cancer Cell Lines for Chemoradiation and Thermoradiation
Published in Cancers (26-04-2021)“…Radiotherapy plus cisplatin (chemoradiation) is standard treatment for women with locoregionally advanced cervical cancer. Both radiotherapy and cisplatin…”
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Elevated temperatures and longer durations improve the efficacy of oxaliplatin- and mitomycin C-based hyperthermic intraperitoneal chemotherapy in a confirmed rat model for peritoneal metastasis of colorectal cancer origin
Published in Frontiers in oncology (16-03-2023)“…In patients with limited peritoneal metastasis (PM) originating from colorectal cancer, cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal…”
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The Temperature-Dependent Effectiveness of Platinum-Based Drugs Mitomycin-C and 5-FU during Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Colorectal Cancer Cell Lines
Published in Cells (Basel, Switzerland) (25-07-2020)“…Cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) is a treatment with curative intent for peritoneal metastasis of…”
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Pre-Operative Decitabine in Colon Cancer Patients: Analyses on WNT Target Methylation and Expression
Published in Cancers (13-05-2021)“…DNA hypermethylation is common in colon cancer. Previously, we have shown that methylation of WNT target genes predicts poor prognosis in stage II colon…”
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Radiosensitization by Hyperthermia Critically Depends on the Time Interval
Published in International journal of radiation oncology, biology, physics (01-03-2024)“…Hyperthermia is a potent sensitizer of radiation therapy that improves both tumor control and survival in women with locally advanced cervical cancer (LACC)…”
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CD40 stimulation sensitizes CLL cells to lysosomal cell death induction by type II anti-CD20 mAb GA101
Published in Blood (10-11-2011)“…Sensitivity of chronic lymphocytic leukemia (CLL) cells to anti-CD20 mAbs is low and, therefore, the efficacy of monotherapy with current anti-CD20 mAbs is…”
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CD40 stimulation sensitizes CLL cells to lysosomal cell death induction by type II anti-CD20mAbGA101
Published in Blood (2011)Get full text
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