Search Results - "van Blokland, Irene V"

Sex differences in leukocyte profile in ST-elevation myocardial infarction patients by van Blokland, Irene V., Groot, Hilde E., Hendriks, Tom, Assa, Solmaz, van der Harst, Pim

“…Background: Whether sex differences exist in the inflammatory response after ST-elevation myocardial infarction (STEMI) remains to be elucidated. We studied…”
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Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data by Li, Shuang, Schmid, Katharina T, de Vries, Dylan H, Korshevniuk, Maryna, Losert, Corinna, Oelen, Roy, van Blokland, Irene V, Groot, Hilde E, Swertz, Morris A, van der Harst, Pim, Westra, Harm-Jan, van der Wijst, Monique G P, Heinig, Matthias, Franke, Lude

“…Expression quantitative trait loci (eQTL) studies show how genetic variants affect downstream gene expression. Single-cell data allows reconstruction of…”
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Translational insights from single-cell technologies across the cardiovascular disease continuum by van Blokland, Irene V., Groot, Hilde E., Franke, Lude H., van der Wijst, Monique G.P., van der Harst, Pim

“…Cardiovascular disease is the leading cause of death worldwide. The societal health burden it represents can be reduced by taking preventive measures and…”
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Association of epicardial adipose tissue with different stages of coronary artery disease: A cross-sectional UK Biobank cardiovascular magnetic resonance imaging substudy by van Meijeren, Anne Ruth, Ties, Daan, de Koning, Marie-Sophie L.Y., van Dijk, Randy, van Blokland, Irene V., Lizana Veloz, Pablo, van Woerden, Gijs, Vliegenthart, Rozemarijn, Pundziute, Gabija, Westenbrink, Daan B., van der Harst, Pim

“…Increased epicardial adipose tissue (EAT) has been identified as a risk factor for the development of coronary artery disease (CAD). However, the exact role of…”
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Leukocyte profiles across the cardiovascular disease continuum: A population-based cohort study by Groot, Hilde E., van Blokland, Irene V., Lipsic, Erik, Karper, Jacco C., van der Harst, Pim

“…Inflammation plays a pivotal role across all stadia of the cardiovascular disease (CVD) continuum, i.e. non-obstructive coronary artery disease (CAD),…”
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Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes by Pekayvaz, Kami, Losert, Corinna, Knottenberg, Viktoria, Gold, Christoph, van Blokland, Irene V., Oelen, Roy, Groot, Hilde E., Benjamins, Jan Walter, Brambs, Sophia, Kaiser, Rainer, Gottschlich, Adrian, Hoffmann, Gordon Victor, Eivers, Luke, Martinez-Navarro, Alejandro, Bruns, Nils, Stiller, Susanne, Akgöl, Sezer, Yue, Keyang, Polewka, Vivien, Escaig, Raphael, Joppich, Markus, Janjic, Aleksandar, Popp, Oliver, Kobold, Sebastian, Petzold, Tobias, Zimmer, Ralf, Enard, Wolfgang, Saar, Kathrin, Mertins, Philipp, Huebner, Norbert, van der Harst, Pim, Franke, Lude H., van der Wijst, Monique G. P., Massberg, Steffen, Heinig, Matthias, Nicolai, Leo, Stark, Konstantin

“…Acute and chronic coronary syndromes (ACS and CCS) are leading causes of mortality. Inflammation is considered a key pathogenic driver of these diseases, but…”
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Single-Cell Dissection of the Immune Response After Acute Myocardial Infarction by van Blokland, Irene V, Oelen, Roy, Groot, Hilde E, Benjamins, Jan Walter, Pekayvaz, Kami, Losert, Corinna, Knottenberg, Viktoria, Heinig, Matthias, Nicolai, Leo, Stark, Konstantin, van der Harst, Pim, Franke, Lude, van der Wijst, Monique G P

“…The immune system's role in ST-segment-elevated myocardial infarction (STEMI) remains poorly characterized but is an important driver of recurrent…”
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Abstract 13873: Ischemic Time and Interleukin 6 Levels in Acute Myocardial Infarction by Groot, Hilde E, van Blokland, Irene V, Karper, Jacco C, van der Harst, Pim, Lipsic, Erik

“…IntroductionIncreased levels of the inflammatory cytokine interleukin 6 (IL-6) after percutaneous coronary intervention (PCI) for ST-elevation myocardial…”
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Using symptom-based case predictions to identify host genetic factors that contribute to COVID-19 susceptibility by Irene V van Blokland, Pauline Lanting, Anil P S Ori, Judith M Vonk, Robert C A Warmerdam, Johanna C Herkert, Floranne Boulogne, Annique Claringbould, Esteban A Lopera-Maya, Meike Bartels, Jouke-Jan Hottenga, Andrea Ganna, Juha Karjalainen, Lifelines COVID-19 cohort study, COVID-19 Host Genetics Initiative, Caroline Hayward, Chloe Fawns-Ritchie, Archie Campbell, David Porteous, Elizabeth T Cirulli, Kelly M Schiabor Barrett, Stephen Riffle, Alexandre Bolze, Simon White, Francisco Tanudjaja, Xueqing Wang, Jimmy M Ramirez, Yan Wei Lim, James T Lu, Nicole L Washington, Eco J C de Geus, Patrick Deelen, H Marike Boezen, Lude H Franke

“…Epidemiological and genetic studies on COVID-19 are currently hindered by inconsistent and limited testing policies to confirm SARS-CoV-2 infection. Recently,…”
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