Search Results - "van Beekveld, M"

Coordination of bilayer properties by an inward-rectifier K+ channel is a cooperative process driven by protein-lipid interaction by van Aalst, Evan J., Yekefallah, Maryam, A. M. van Beekveld, Roy, Breukink, Eefjan, Weingarth, Markus, Wylie, Benjamin J.

“…[Display omitted] •KirBac1.1 is gated by anionic PG lipids, and nucleates bilayer ordering.•The extent of ordering and bilayer Tm are dependent on PG…”
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Teixobactin kills bacteria by a two-pronged attack on the cell envelope by Shukla, Rhythm, Lavore, Francesca, Maity, Sourav, Derks, Maik G. N., Jones, Chelsea R., Vermeulen, Bram J. A., Melcrová, Adéla, Morris, Michael A., Becker, Lea Marie, Wang, Xiaoqi, Kumar, Raj, Medeiros-Silva, João, van Beekveld, Roy A. M., Bonvin, Alexandre M. J. J., Lorent, Joseph H., Lelli, Moreno, Nowick, James S., MacGillavry, Harold D., Peoples, Aaron J., Spoering, Amy L., Ling, Losee L., Hughes, Dallas E., Roos, Wouter H., Breukink, Eefjan, Lewis, Kim, Weingarth, Markus

“…Antibiotics that use novel mechanisms are needed to combat antimicrobial resistance 1 – 3 . Teixobactin 4 represents a new class of antibiotics with a unique…”
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Specific Lipid Studies in Complex Membranes by Solid‐State NMR Spectroscopy by Beekveld, Roy A. M., Derks, Maik G. N., Kumar, Raj, Smid, Leanna, Maass, Thorben, Medeiros‐Silva, João, Breukink, Eefjan, Weingarth, Markus

“…Specific interactions with phospholipids are often critical for the function of proteins or drugs, but studying these interactions at high resolution remains…”
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The Dark Machines Anomaly Score Challenge: Benchmark Data and Model Independent Event Classification for the Large Hadron Collider by Aarrestad, Thea, van Beekveld, Melissa, Bona, Marcella, Boveia, Antonio, Caron, Sascha, Davies, Joe, de Simone, Andrea, Doglioni, Caterina, Duarte, Javier, Farbin, Amir, Gupta, Honey, Hendriks, Luc, Heinrich, Lukas A., Howarth, James, Jawahar, Pratik, Jueid, Adil, Lastow, Jessica, Leinweber, Adam, Mamuzic, Judita, Merényi, Erzsébet, Morandini, Alessandro, Moskvitina, Polina, Nellist, Clara, Ngadiuba, Jennifer, Ostdiek, Bryan, Pierini, Maurizio, Ravina, Baptiste, Ruiz de Austri, Roberto, Sekmen, Sezen, Touranakou, Mary, Vaškeviciute, Marija, Vilalta, Ricardo, Vlimant, Jean-Roch, Verheyen, Rob, White, Martin, Wulff, Eric, Wallin, Erik, Wozniak, Kinga A., Zhang, Zhongyi

“…We describe the outcome of a data challenge conducted as part of the Dark Machines (https://www.darkmachines.org) initiative and the Les Houches 2019 workshop…”
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Analyzing mechanisms of action of antimicrobial peptides on bacterial membranes requires multiple complimentary assays and different bacterial strains by Wang, Xiaoqi, van Beekveld, Roy A M, Xu, Yang, Parmar, Anish, Das, Sanjit, Singh, Ishwar, Breukink, Eefjan

“…Antimicrobial peptides (AMPs) commonly target bacterial membranes and show broad-spectrum activity against microorganisms. In this research we used three AMPs…”
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Cooperative Gating of a K+ Channel by Unmodified Biological Anionic Lipids Viewed by Solid-State NMR Spectroscopy by Yekefallah, Maryam, van Aalst, Evan J., van Beekveld, Roy A. M., Eason, Isaac R., Breukink, Eefjan, Weingarth, Markus, Wylie, Benjamin J.

“…Lipids adhere to membrane proteins to stimulate or suppress molecular and ionic transport and signal transduction. Yet, the molecular details of lipid–protein…”
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The Dark Machines Anomaly Score Challenge: Benchmark Data and Model Independent Event Classification for the Large Hadron Collider by Aarrestad, T, van Beekveld, M, Bona, M, Boveia, A, Caron, S, Davies, J, De Simone, A, Doglioni, C, Duarte, J. M, Farbin, A, Gupta, H, Hendriks, L, Heinrich, L, Howarth, J, Jawahar, P, Jueid, A, Lastow, J, Leinweber, A, Mamuzic, J, Merényi, E, Morandini, A, Moskvitina, P, Nellist, C, Ngadiuba, J, Ostdiek, B, Pierini, M, Ravina, B, de Austri, R. Ruiz, Sekmen, S, Touranakou, M, Vaškevičiūte, M, Vilalta, R, Vlimant, J. R, Verheyen, R, White, M, Wulff, E, Wallin, E, Wozniak, K. A, Zhang, Z

“…SciPost Phys. 12, 043 (2022) We describe the outcome of a data challenge conducted as part of the Dark Machines Initiative and the Les Houches 2019 workshop on…”
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A comparison of optimisation algorithms for high-dimensional particle and astrophysics applications by Balázs, Csaba, van Beekveld, Melissa, Caron, Sascha, Dillon, Barry M., Farmer, Ben, Fowlie, Andrew, Garrido-Merchán, Eduardo C., Handley, Will, Hendriks, Luc, Jóhannesson, Guðlaugur, Leinweber, Adam, Mamužić, Judita, Martinez, Gregory D., Otten, Sydney, de Austri, Roberto Ruiz, Scott, Pat, Searle, Zachary, Stienen, Bob, Vanschoren, Joaquin, White, Martin

“…A bstract Optimisation problems are ubiquitous in particle and astrophysics, and involve locating the optimum of a complicated function of many parameters that…”
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Les Houches 2019 Physics at TeV Colliders: New Physics Working Group Report by Brooijmans, G, Buckley, A, Caron, S, Falkowski, A, Fuks, B, Gilbert, A, Murray, W. J, Nardecchia, M, No, J. M, Torre, R, You, T, Della Porta, G. Zevi, Alguero, G, Araz, J. Y, Banerjee, S, Bélanger, G, Berger-Hryn'ova, T, Bernigaud, J, Bharucha, A, Buttazzo, D, Butterworth, J. M, Cacciapaglia, G, Coccaro, A, Corpe, L, Desai, N, De Simone, A, Dutta, J, Farbin, A, Fichet, S, Flacke, T, Ganguly, S, Gascon-Shotkin, S, Gonzalo, T, Goudelis, A, Gras, P, Gupta, R. S, Habedank, M, Heisig, J, Hendriks, L, Jain, S, Jueid, A, Kar, D, Kraml, S, Kvellestad, A, Lane, K. D, Langford, J, Leinweber, A, Lesauvage, A, Lessa, A, Mamuzic, J, Marzocca, D, Merényi, E, Mjallal, A, Mohan, K. A, Morandini, A, Moreau, G, Mutzel, S, Nellist, C, Otten, S, Pani, P, Panizzi, L, Pierini, M, Polesello, G, Porod, W, Prosper, H. B, Pukhov, A, Quevillon, J, Raklev, A, Reyes-González, H, Ruiz, R, de Austri, R. Ruiz, Schouwenberg, J, Sekmen, S, Sengupta, D, Smith, C, Son, M, Sperka, D, Stienen, B, Tobioka, K, van Beekveld, M, Venturini, E, Vignaroli, N, Vilalta, R, Waltenberger, W, Wardle, N, Watt, G, White, M, Williamson, S. L, Yallup, D, Zurita, J

“…This report presents the activities of the `New Physics' working group for the `Physics at TeV Colliders' workshop (Les Houches, France, 10--28 June, 2019)…”
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