Search Results - "van Beek, Lianne"

From decision to reflection: understanding the experiences and unmet care needs of patients treated with immunotherapy for melanoma in the adjuvant or metastatic setting by Kamminga, Nadia C W, van der Veldt, Astrid A M, Wakkee, Marlies, van den Berge, Fauve R, van der Beek, Lianne A A, Joosen, Margot C W, Joosse, Arjen, de Joode, Karlijn, Nijsten, Tamar E C, Lugtenberg, Marjolein

“…Despite increased use of immune checkpoint inhibitors (ICIs) in patients with advanced melanoma, little is known about patient experiences during this…”
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Increased systemic and adipose tissue inflammation differentiates obese women with T2DM from obese women with normal glucose tolerance by van Beek, Lianne, Lips, Mirjam A, Visser, Annemieke, Pijl, Hanno, Ioan-Facsinay, Andreea, Toes, René, Berends, Frits J, Willems van Dijk, Ko, Koning, Frits, van Harmelen, Vanessa

“…Abstract Introduction Obesity is strongly related to type-2 diabetes (T2DM), but there is a subset of obese individuals that remains relatively insulin…”
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Comparison of osteoblast and cardiomyocyte differentiation in the embryonic stem cell test for predicting embryotoxicity in vivo by de Jong, Esther, van Beek, Lianne, Piersma, Aldert H.

“…One of the most studied alternative embryotoxicity assays is the embryonic stem cell test, in which the effect of compounds on cardiomyocyte differentiation is…”
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Mannose-binding lectin is required for the effective clearance of apoptotic cells by adipose tissue macrophages during obesity by Stienstra, Rinke, Dijk, Wieneke, van Beek, Lianne, Jansen, Henry, Heemskerk, Mattijs, Houtkooper, Riekelt H, Denis, Simone, van Harmelen, Vanessa, Willems van Dijk, Ko, Tack, Cees J, Kersten, Sander

“…Obesity is accompanied by the presence of chronic low-grade inflammation manifested by infiltration of macrophages into adipose tissue. Mannose-binding lectin…”
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A Restricted Role for FcγR in the Regulation of Adaptive Immunity by Fransen, Marieke F, Benonisson, Hreinn, van Maren, Wendy W, Sow, Heng Sheng, Breukel, Cor, Linssen, Margot M, Claassens, Jill W C, Brouwers, Conny, van der Kaa, Jos, Camps, Marcel, Kleinovink, Jan Willem, Vonk, Kelly K, van Heiningen, Sandra, Klar, Ngaisah, van Beek, Lianne, van Harmelen, Vanessa, Daxinger, Lucia, Nandakumar, Kutty S, Holmdahl, Rikard, Coward, Chris, Lin, Qingshun, Hirose, Sachiko, Salvatori, Daniela, van Hall, Thorbald, van Kooten, Cees, Mastroeni, Piero, Ossendorp, Ferry, Verbeek, J Sjef

“…By their interaction with IgG immune complexes, FcγR and complement link innate and adaptive immunity, showing functional redundancy. In complement-deficient…”
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BMT decreases HFD-induced weight gain associated with decreased preadipocyte number and insulin secretion by Katiraei, Saeed, Hoving, Lisa R, van Beek, Lianne, Mohamedhoesein, Sharida, Carlotti, Françoise, van Diepen, Janna A, Rensen, Patrick C N, Netea, Mihai G, Willems van Dijk, Ko, Berbée, Jimmy F P, van Harmelen, Vanessa

“…Experimental bone marrow transplantation (BMT) in mice is commonly used to assess the role of immune cell-specific genes in various pathophysiological…”
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Osteoblast differentiation of murine embryonic stem cells as a model to study the embryotoxic effect of compounds by de Jong, Esther, van Beek, Lianne, Piersma, Aldert H.

“…► We developed a osteoblast differentiation model (ESTo). ► A correlation was found between effects on calcium concentrations and cytotoxicity. ► Gene…”
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Chronic helminth infection and helminth‐derived egg antigens promote adipose tissue M2 macrophages and improve insulin sensitivity in obese mice by Hussaarts, Leonie, García‐Tardón, Noemí, Beek, Lianne, Heemskerk, Mattijs M., Haeberlein, Simone, Zon, Gerard C., Ozir‐Fazalalikhan, Arifa, Berbée, Jimmy F. P., Dijk, Ko Willems, Harmelen, Vanessa, Yazdanbakhsh, Maria, Guigas, Bruno

“…ABSTRACT Chronic low‐grade inflammation associated with obesity contributes to insulin resistance and type 2 diabetes. Helminth parasites are the strongest…”
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The limited storage capacity of gonadal adipose tissue directs the development of metabolic disorders in male C57Bl/6J mice by van Beek, Lianne, van Klinken, Jan B., Pronk, Amanda C. M., van Dam, Andrea D., Dirven, Eline, Rensen, Patrick C. N., Koning, Frits, Willems van Dijk, Ko, van Harmelen, Vanessa

“…Aims/hypothesis White adipose tissue (WAT) consists of various depots with different adipocyte functionality and immune cell composition. Knowledge of…”
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Splenic autonomic denervation increases inflammatory status but does not aggravate atherosclerotic lesion development by Kooijman, Sander, Meurs, Illiana, van Beek, Lianne, Khedoe, P Padmini S J, Giezekamp, Annabel, Pike-Overzet, Karin, Cailotto, Cathy, van der Vliet, Jan, van Harmelen, Vanessa, Boeckxstaens, Guy, Berbée, Jimmy F P, Rensen, Patrick C N

“…The brain plays a prominent role in the regulation of inflammation. Immune cells are under control of the so-called cholinergic anti-inflammatory reflex,…”
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Identification of a selective glucocorticoid receptor modulator that prevents both diet‐induced obesity and inflammation by Heuvel, José K, Boon, Mariëtte R, Hengel, Ingmar, Peschier‐van der Put, Emma, Beek, Lianne, Harmelen, Vanessa, Dijk, Ko Willems, Pereira, Alberto M, Hunt, Hazel, Belanoff, Joseph K, Rensen, Patrick C N, Meijer, Onno C

“…Background and Purpose High‐fat diet consumption results in obesity and chronic low‐grade inflammation in adipose tissue. Whereas glucocorticoid receptor (GR)…”
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BCG lowers plasma cholesterol levels and delays atherosclerotic lesion progression in mice by van Dam, Andrea D, Bekkering, Siroon, Crasborn, Malou, van Beek, Lianne, van den Berg, Susan M, Vrieling, Frank, Joosten, Simone A, van Harmelen, Vanessa, de Winther, Menno P.J, Lütjohann, Dieter, Lutgens, Esther, Boon, Mariëtte R, Riksen, Niels P, Rensen, Patrick C.N, Berbée, Jimmy F.P

“…Abstract Background and aims Bacille-Calmette-Guérin (BCG), prepared from attenuated live Mycobacterium bovis , modulates atherosclerosis development as…”
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Short-term high-fat diet increases macrophage markers in skeletal muscle accompanied by impaired insulin signalling in healthy male subjects by Boon, Mariëtte R, Bakker, Leontine E H, Haks, Mariëlle C, Quinten, Edwin, Schaart, Gert, Van Beek, Lianne, Wang, Yanan, Van Schinkel, Linda, Van Harmelen, Vanessa, Meinders, A Edo, Ottenhoff, Tom H M, Van Dijk, Ko Willems, Guigas, Bruno, Jazet, Ingrid M, Rensen, Patrick C N

“…Macrophage markers in skeletal muscle of obese subjects are elevated and inversely relate to insulin sensitivity. The present study aimed to investigate…”
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FcRγ‐chain deficiency reduces the development of diet‐induced obesity by van Beek, Lianne, Vroegrijk, Irene O.C.M., Katiraei, Saeed, Heemskerk, Mattijs M., van Dam, Andrea D., Kooijman, Sander, Rensen, Patrick C.N., Koning, Frits, Verbeek, J. Sjef, Willems van Dijk, Ko, van Harmelen, Vanessa

“…Objective Pathogenic immunoglobulins are produced during the development of obesity and contribute to the development of insulin resistance (IR). However, the…”
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F c R γ‐chain deficiency reduces the development of diet‐induced obesity by van Beek, Lianne, Vroegrijk, Irene O.C.M., Katiraei, Saeed, Heemskerk, Mattijs M., van Dam, Andrea D., Kooijman, Sander, Rensen, Patrick C.N., Koning, Frits, Verbeek, J. Sjef, Willems van Dijk, Ko, van Harmelen, Vanessa

“…Objective Pathogenic immunoglobulins are produced during the development of obesity and contribute to the development of insulin resistance (IR). However, the…”
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FcR[gamma]-Chain Deficiency Reduces the Development of Diet-Induced Obesity by van Beek, Lianne, Vroegrijk, Irene O C M, Katiraei, Saeed, Heemskerk, Mattijs M, van Dam, Andrea D, Kooijman, Sander, Rensen, Patrick C N, Koning, Frits, Verbeek, J Sjef, van Dijk, Ko Willems, van Harmelen, Vanessa

“…Pathogenic immunoglobulins are produced during the development of obesity and contribute to the development of insulin resistance (IR). However, the mechanisms…”
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The effect of five teratogenic compounds on the differentiation of murine embryonic stem cells into osteoblasts by de Jong, Esther, van Beek, Lianne, Piersma, Aldert H.

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PS13 - 3. Fcγ- and ε-receptors do not play a role in the initial development of insulin resistance by van Beek, Lianne, Vroegrijk, Irene, Pronk, Amanda, Koning, Frits, Verbeek, Sjef, van Dijk, Ko Willems, van Harmelen, Vanessa

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PS19 - 88. Mast cell deficient mice on a high fat diet have altered immune cell infiltration in their adipose tissue by van Beek, Lianne, Bot, Ilze, Pronk, Amanda, van Dijk, Ko Willems, Koning, Frits, van Harmelen, Vanessa

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PS13 - 5. Protective effect of chronic helminth infection against diet-induced obesity by Guigas, Bruno, Hussaarts, Leonie, van Beek, Lianne, Heemskerk, Mattijs M., Haeberlein, Simone, Berbee, Jimmy F., van Harmelen, Vanessa, van Dijk, Ko Willems, Yazdanbakhsh, Maria

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