Search Results - "van Beek, Jasper J P"

A fresh look at the T helper subset dogma by van Beek, Jasper J. P., Rescigno, Maria, Lugli, Enrico

“…Single-cell-sequencing techniques enable the decades-old T helper subset dogma to be re-examined in an unsupervised manner, bringing nuance to the definition…”
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Naturally produced type I IFNs enhance human myeloid dendritic cell maturation and IL-12p70 production and mediate elevated effector functions in innate and adaptive immune cells by Sköld, Annette E., Mathan, Till S. M., van Beek, Jasper J. P., Flórez-Grau, Georgina, van den Beukel, Michelle D., Sittig, Simone P., Wimmers, Florian, Bakdash, Ghaith, Schreibelt, Gerty, de Vries, I. Jolanda M.

“…There has recently been a paradigm shift in the field of dendritic cell (DC)-based immunotherapy, where several clinical studies have confirmed the feasibility…”
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Insight into Mucinous Colorectal Carcinoma: Clues from Etiology by Hugen, Niek, van Beek, Jasper J. P., de Wilt, Johannes H. W., Nagtegaal, Iris D.

“…The prognostic impact of mucinous carcinoma (MC) in colorectal cancer (CRC) has been subject to debate ever since the introduction of the classification of…”
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Human type 1 and type 2 conventional dendritic cells express indoleamine 2,3‐dioxygenase 1 with functional effects on T cell priming by Sittig, Simone P., van Beek, Jasper J. P., Flórez‐Grau, Georgina, Weiden, Jorieke, Buschow, Sonja I., van der Net, Mirjam C., van Slooten, Rianne, Verbeek, Marcel M., Geurtz, P. Ben H., Textor, Johannes, Figdor, Carl G., de Vries, I. Jolanda M., Schreibelt, Gerty

“…Dendritic cells (DCs) are key regulators of the immune system that shape T cell responses. Regulation of T cell induction by DCs may occur via the…”
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Single-cell profiling reveals the dynamics of cytomegalovirus-specific T cells in haploidentical hematopoietic stem cell transplantation by Van Beek, Jasper J. P., Puccio, Simone, Roberto, Alessandra, De Paoli, Federica, Graziano, Giulia, Salviato, Elisa, Alvisi, Giorgia, Zanon, Veronica, Scarpa, Alice, Zaghi, Elisa, Calvi, Michela, Di Vito, Clara, Mineri, Rossana, Sarina, Barbara, De Philippis, Chiara, Santoro, Armando, Mariotti, Jacopo, Bramanti, Stefania, Ferrari, Francesco, Castagna, Luca, Mavilio, Domenico, Lugli, Enrico

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Protamine-stabilized RNA as an ex vivo stimulant of primary human dendritic cell subsets by Sköld, Annette E., van Beek, Jasper J. P., Sittig, Simone P., Bakdash, Ghaith, Tel, Jurjen, Schreibelt, Gerty, de Vries, I. Jolanda M.

“…Dendritic cells (DCs) are key in connecting innate and adaptive immunity. Their potential in inducing specific immune responses has made them interesting…”
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Human blood myeloid and plasmacytoid dendritic cells cross activate each other and synergize in inducing NK cell cytotoxicity by van Beek, Jasper J. P., Gorris, Mark A. J., Sköld, Annette E., Hatipoglu, Ibrahim, Van Acker, Heleen H., Smits, Evelien L., de Vries, I. Jolanda M., Bakdash, Ghaith

“…Human blood dendritic cells (DCs) hold great potential for use in anticancer immunotherapies. CD1c + myeloid DCs and plasmacytoid DCs (pDCs) have been…”
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Long COVID-19 Cardiac Complications Are Associated With Autoimmunity to Cardiac Self-Antigens Sufficient to Cause Cardiac Dysfunction by Cremonesi, Marco, Felicetta, Arianna, Cannata, Francesco, Serio, Simone, van Beek, Jasper J P, Bombace, Sara, My, Ilaria, Zanon, Veronica, Catalano, Chiara, Papadopoulou, Vasiliki, Monti, Lorenzo, Chiarito, Mauro, Stefanini, Giulio, Panico, Cristina, Francone, Marco, Lugli, Enrico, Kallikourdis, Marinos, Condorelli, Gianluigi

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Pre-existing chromatin accessibility and gene expression differences among naive CD4 + T cells influence effector potential by Rogers, Dakota, Sood, Aditi, Wang, HanChen, van Beek, Jasper J P, Rademaker, Thomas J, Artusa, Patricio, Schneider, Caitlin, Shen, Connie, Wong, Dylan C, Bhagrath, Aanya, Lebel, Marie-Ève, Condotta, Stephanie A, Richer, Martin J, Martins, Andrew J, Tsang, John S, Barreiro, Luis B, François, Paul, Langlais, David, Melichar, Heather J, Textor, Johannes, Mandl, Judith N

“…CD4 T cells have a remarkable potential to differentiate into diverse effector lineages following activation. Here, we probe the heterogeneity present among…”
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Human pDCs Are Superior to cDC2s in Attracting Cytolytic Lymphocytes in Melanoma Patients Receiving DC Vaccination by van Beek, Jasper J.P., Flórez-Grau, Georgina, Gorris, Mark A.J., Mathan, Till S.M., Schreibelt, Gerty, Bol, Kalijn F., Textor, Johannes, de Vries, I. Jolanda M.

“…Plasmacytoid dendritic cells (pDCs) and type 2 conventional dendritic cells (cDC2s) are currently under evaluation for use in cancer vaccines. Although both DC…”
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Selected memory T cells infused post–haploidentical hematopoietic stem cell transplantation persist and hyperexpand by van Beek, Jasper J. P., Puccio, Simone, Di Vito, Clara, De Paoli, Federica, Zaghi, Elisa, Calvi, Michela, Scarpa, Alice, Peano, Clelia, Basso, Gianluca, Cibella, Javier, De Philippis, Chiara, Sarina, Barbara, Timofeeva, Inna, Capizzuto, Rossana, Mannina, Daniele, Mineri, Rossana, Mariotti, Jacopo, Crocchiolo, Roberto, Santoro, Armando, Castagna, Luca, Bramanti, Stefania, Mavilio, Domenico, Lugli, Enrico

“…•Infusions of donor memory T-cells after haplo-HSCT lead to engraftment, persistence, and prominent expansion of selected T-cell clones.•Infused patients…”
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Feasibility and Efficacy of CD45RA+ Depleted Donor Lymphocytes Infusion After Haploidentical Transplantation With Post-Transplantation Cyclophosphamide in Patients With Hematological Malignancies by Castagna, Luca, Valli, Viviana, Timofeeva, Inna, Capizzuto, Rossana, Bramanti, Stefania, Mariotti, Jacopo, De Philippis, Chiara, Sarina, Barbara, Mannina, Daniele, Giordano, Laura, De Paoli, Federica, van Beek, Jasper J.P., Zaghi, Elisa, Calvi, Michela, Vito, Clara Di, Mavilio, Domenico, Crocchiolo, Roberto, Lugli, Enrico

“…Allogeneic stem cell transplantation from haploidentical donor using post-transplantation cyclophosphamide has been used to cure hematological diseases…”
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Dendritic cell cross talk with innate and innate-like effector cells in antitumor immunity: implications for DC vaccination by van Beek, Jasper J P, Wimmers, Florian, Hato, Stanleyson V, de Vries, I Jolanda M, Sköld, Annette E

“…Dendritic cells (DCs) are key players in the induction of immune responses. Adoptive transfer of autologous mature DCs loaded with tumor-associated antigens is…”
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Innate Lymphoid Cells in Tumor Immunity by van Beek, Jasper J P, Martens, Anne W J, Bakdash, Ghaith, de Vries, I Jolanda M

“…Innate lymphoid cells (ILCs) are a group of immune cells of the lymphoid lineage that do not possess antigen specificity. The group includes natural killer…”
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Single-cell profiling identifies impaired adaptive NK cells expanded after HCMV reactivation in haploidentical HSCT by Zaghi, Elisa, Calvi, Michela, Puccio, Simone, Spata, Gianmarco, Terzoli, Sara, Peano, Clelia, Roberto, Alessandra, De Paoli, Federica, van Beek, Jasper Jp, Mariotti, Jacopo, De Philippis, Chiara, Sarina, Barbara, Mineri, Rossana, Bramanti, Stefania, Santoro, Armando, Le-Trilling, Vu Thuy Khanh, Trilling, Mirko, Marcenaro, Emanuela, Castagna, Luca, Di Vito, Clara, Lugli, Enrico, Mavilio, Domenico

“…Haploidentical hematopoietic stem cell transplantation (h-HSCT) represents an efficient curative approach for patients affected by hematologic malignancies in…”
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