Search Results - "van Schaik, Willem"

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  1. 1

    Genomic transition of enterococci from gut commensals to leading causes of multidrug-resistant hospital infection in the antibiotic era by Gilmore, Michael S, Lebreton, Francois, van Schaik, Willem

    Published in Current opinion in microbiology (01-02-2013)
    “…Highlights ► Enterococci are ancient commensals in the GI tracts of hosts ranging from insects to man. ► Enterococci are now leading causes of multidrug…”
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    Limited influence of hospital wastewater on the microbiome and resistome of wastewater in a community sewerage system by Buelow, Elena, Bayjanov, Jumamurat R, Majoor, Eline, Willems, Rob Jl, Bonten, Marc Jm, Schmitt, Heike, van Schaik, Willem

    Published in FEMS microbiology ecology (01-07-2018)
    “…Effluents from wastewater treatment plants (WWTPs) have been proposed to act as point sources of antibiotic-resistant bacteria (ARB) and antimicrobial…”
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    Core Genome Multilocus Sequence Typing Scheme for High- Resolution Typing of Enterococcus faecium by de Been, Mark, Pinholt, Mette, Top, Janetta, Bletz, Stefan, Mellmann, Alexander, van Schaik, Willem, Brouwer, Ellen, Rogers, Malbert, Kraat, Yvette, Bonten, Marc, Corander, Jukka, Westh, Henrik, Harmsen, Dag, Willems, Rob J L

    Published in Journal of clinical microbiology (01-12-2015)
    “…Enterococcus faecium, a common inhabitant of the human gut, has emerged in the last 2 decades as an important multidrug-resistant nosocomial pathogen. Since…”
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  5. 5

    The human gut resistome by van Schaik, Willem

    “…In recent decades, the emergence and spread of antibiotic resistance among bacterial pathogens has become a major threat to public health. Bacteria can acquire…”
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    CRISPR-Cas9-mediated genome editing in vancomycin-resistant Enterococcus faecium by de Maat, Vincent, Stege, Paul B, Dedden, Mark, Hamer, Maud, van Pijkeren, Jan-Peter, Willems, Rob J L, van Schaik, Willem

    Published in FEMS microbiology letters (01-11-2019)
    “…ABSTRACT The Gram-positive bacterium Enterococcus faecium is becoming increasingly prevalent as a cause of hospital-acquired, antibiotic-resistant infections…”
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    Genome-wide identification of ampicillin resistance determinants in Enterococcus faecium by Zhang, Xinglin, Paganelli, Fernanda L, Bierschenk, Damien, Kuipers, Annemarie, Bonten, Marc J M, Willems, Rob J L, van Schaik, Willem

    Published in PLoS genetics (01-06-2012)
    “…Enterococcus faecium has become a nosocomial pathogen of major importance, causing infections that are difficult to treat owing to its multi-drug resistance…”
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    Nonclonal Emergence of Colistin Resistance Associated with Mutations in the BasRS Two-Component System in Escherichia coli Bloodstream Isolates by Janssen, Axel B, Bartholomew, Toby L, Marciszewska, Natalia P, Bonten, Marc J M, Willems, Rob J L, Bengoechea, Jose A, van Schaik, Willem

    Published in mSphere (11-03-2020)
    “…Infections by multidrug-resistant Gram-negative bacteria are increasingly common, prompting the renewed interest in the use of colistin. Colistin specifically…”
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  12. 12

    Global Regulator CodY Regulates Toxin Gene Expression in Bacillus anthracis and Is Required for Full Virulence by van Schaik, Willem, Château, Alice, Dillies, Marie-Agnès, Coppée, Jean-Yves, Sonenshein, Abraham L, Fouet, Agnès

    Published in Infection and Immunity (01-10-2009)
    “…In gram-positive bacteria, CodY is an important regulator of genes whose expression changes upon nutrient limitation and acts as a repressor of virulence gene…”
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  13. 13

    Horizontal transfer of antibiotic resistance genes in the human gut microbiome by McInnes, Ross S, McCallum, Gregory E, Lamberte, Lisa E, van Schaik, Willem

    Published in Current opinion in microbiology (01-02-2020)
    “…•The human gut microbiome harbours antibiotic resistance genes (‘the resistome’).•Antibiotic resistance genes can spread in the gut microbiome through…”
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  14. 14

    Characterization of Enterococcus Isolates Colonizing the Intestinal Tract of Intensive Care Unit Patients Receiving Selective Digestive Decontamination by Bello Gonzalez, Teresita D J, Pham, Phu, Top, Janetta, Willems, Rob J L, van Schaik, Willem, van Passel, Mark W J, Smidt, Hauke

    Published in Frontiers in microbiology (28-08-2017)
    “…Enterococci have emerged as important opportunistic pathogens in intensive care units (ICUs). In this study, enterococcal population size and isolates…”
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  15. 15

    Challenges and opportunities for whole‐genome sequencing–based surveillance of antibiotic resistance by Schürch, Anita C., Schaik, Willem

    Published in Annals of the New York Academy of Sciences (01-01-2017)
    “…Infections caused by drug‐resistant bacteria are increasingly reported across the planet, and drug‐resistant bacteria are recognized to be a major threat to…”
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    Baas Becking meets One Health by van Schaik, Willem

    Published in Nature microbiology (01-04-2022)
    “…“Everything is everywhere, but, the environment selects” — a hypothesis formulated by Lourens Baas Becking in 1934 — is used to frame research that analyses…”
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    Whole-Genome Sequencing of Bacterial Pathogens: the Future of Nosocomial Outbreak Analysis by Quainoo, Scott, Coolen, Jordy P M, van Hijum, Sacha A F T, Huynen, Martijn A, Melchers, Willem J G, van Schaik, Willem, Wertheim, Heiman F L

    Published in Clinical microbiology reviews (01-10-2017)
    “…Outbreaks of multidrug-resistant bacteria present a frequent threat to vulnerable patient populations in hospitals around the world. Intensive care unit (ICU)…”
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    The Recombinase IntA Is Required for Excision of esp-Containing ICEEfm1 in Enterococcus faecium by TOP, Janetta, SINNIGE, Jan C, MAJOOR, Eline A. M, BONTEN, Marc J. M, WILLEMS, Rob J. L, VAN SCHAIK, Willem

    Published in Journal of Bacteriology (01-02-2011)
    “…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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    Identification of a Novel Genomic Island Specific to Hospital-Acquired Clonal Complex 17 Enterococcus faecium Isolates by Heikens, Esther, van Schaik, Willem, Leavis, Helen L, Bonten, Marc J.M, Willems, Rob J.L

    Published in Applied and Environmental Microbiology (01-11-2008)
    “…Hospital-acquired clonal complex 17 (CC17) Enterococcus faecium strains are genetically distinct from indigenous strains and are enriched with resistance genes…”
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    On the (im)possibility of reconstructing plasmids from whole-genome short-read sequencing data by Arredondo-Alonso, Sergio, Willems, Rob J, van Schaik, Willem, Schürch, Anita C

    Published in Microbial genomics (01-10-2017)
    “…To benchmark algorithms for automated plasmid sequence reconstruction from short-read sequencing data, we selected 42 publicly available complete bacterial…”
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