Search Results - "ten Berge, Derk"

Wnt signaling mediates self-organization and axis formation in embryoid bodies by ten Berge, Derk, Koole, Wouter, Fuerer, Christophe, Fish, Matt, Eroglu, Elif, Nusse, Roel

“…Embryonic stem cells (ESCs) form descendants of all three germ layers when differentiated as aggregates, termed embryoid bodies. In vivo, differentiation of…”
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In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states by Neagu, Alex, van Genderen, Emiel, Escudero, Irene, Verwegen, Lucas, Kurek, Dorota, Lehmann, Johannes, Stel, Jente, Dirks, René A. M., van Mierlo, Guido, Maas, Alex, Eleveld, Cindy, Ge, Yang, den Dekker, Alexander. T., Brouwer, Rutger W. W., van IJcken, Wilfred F. J., Modic, Miha, Drukker, Micha, Jansen, Joop H., Rivron, Nicolas C., Baart, Esther B., Marks, Hendrik, ten Berge, Derk

“…Following implantation, the naive pluripotent epiblast of the mouse blastocyst generates a rosette, undergoes lumenogenesis and forms the primed pluripotent…”
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Initiation of Proximal-Distal Patterning in the Vertebrate Limb by Signals and Growth by Cooper, Kimberly L., Hu, Jimmy Kuang-Hsien, Berge, Derk ten, Fernandez-Teran, Marian, Ros, Maria A., Tabin, Clifford J.

“…Two broad classes of models have been proposed to explain the patterning of the proximal-distal axis of the vertebrate limb (from the shoulder to the digit…”
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Wnt signaling regulates pancreatic β cell proliferation by Rulifson, Ingrid C, Karnik, Satyajit K, Heiser, Patrick W, ten Berge, Derk, Chen, Hainan, Gu, Xueying, Taketo, Makoto M, Nusse, Roel, Hebrok, Matthias, Kim, Seung K

“…There is widespread interest in defining factors and mechanisms that stimulate proliferation of pancreatic islet cells. Wnt signaling is an important regulator…”
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Bone Regeneration Is Regulated by Wnt Signaling by Kim, Jae‐Beom, Leucht, Philipp, Lam, Kentson, Luppen, Cynthia, Ten Berge, Derk, Nusse, Roel, Helms, Jill A

“…Tissue regeneration is increasingly viewed as reactivation of a developmental process that, when misappropriated, can lead to malignant growth. Therefore,…”
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Endogenous WNT signals mediate BMP-induced and spontaneous differentiation of epiblast stem cells and human embryonic stem cells by Kurek, Dorota, Neagu, Alex, Tastemel, Melodi, Tüysüz, Nesrin, Lehmann, Johannes, van de Werken, Harmen J G, Philipsen, Sjaak, van der Linden, Reinier, Maas, Alex, van IJcken, Wilfred F J, Drukker, Micha, Ten Berge, Derk

“…Therapeutic application of human embryonic stem cells (hESCs) requires precise control over their differentiation. However, spontaneous differentiation is…”
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Long-Term Expansion, Enhanced Chondrogenic Potential, and Suppression of Endochondral Ossification of Adult Human MSCs via WNT Signaling Modulation by Narcisi, Roberto, Cleary, Mairéad A., Brama, Pieter A.J., Hoogduijn, Martin J., Tüysüz, Nesrin, ten Berge, Derk, van Osch, Gerjo J.V.M.

“…Mesenchymal stem cells (MSCs) are a potential source of chondrogenic cells for the treatment of cartilage disorders, but loss of chondrogenic potential during…”
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Xist and Tsix Transcription Dynamics Is Regulated by the X-to-Autosome Ratio and Semistable Transcriptional States by Loos, Friedemann, Maduro, Cheryl, Loda, Agnese, Lehmann, Johannes, Kremers, Gert-Jan, ten Berge, Derk, Grootegoed, J. Anton, Gribnau, Joost

“…In female mammals, X chromosome inactivation (XCI) is a key process in the control of gene dosage compensation between X-linked genes and autosomes. Xist and…”
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Wnt3a protein reduces growth factor-driven expansion of human hematopoietic stem and progenitor cells in serum-free cultures by Duinhouwer, Lucia E, Tüysüz, Nesrin, Rombouts, Elwin W J C, Ter Borg, Mariette N D, Mastrobattista, Enrico, Spanholtz, Jan, Cornelissen, Jan J, Ten Berge, Derk, Braakman, Eric

“…Ex vivo expansion of hematopoietic stem and progenitor cells (HSPC) is a promising approach to improve insufficient engraftment after umbilical cord blood stem…”
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Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells by Berge, Derk ten, Kurek, Dorota, Blauwkamp, Tim, Koole, Wouter, Maas, Alex, Eroglu, Elif, Siu, Ronald K, Nusse, Roel

“…Pluripotent stem cells exist in naive and primed states, epitomized by mouse embryonic stem cells (ESCs) and the developmentally more advanced epiblast stem…”
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Anti-proliferative action of vitamin D in MCF7 is still active after siRNA-VDR knock-down by Costa, José L, Eijk, Paul P, van de Wiel, Mark A, ten Berge, Derk, Schmitt, Fernando, Narvaez, Carmen J, Welsh, JoEllen, Ylstra, Bauke

“…The active form of Vitamin D, 1,25-dihydroxyvitamin D3 (1,25D), has strong anti-proliferative effects, yet the molecular mechanisms underneath this effect…”
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Prx1 and Prx2 in skeletogenesis: roles in the craniofacial region, inner ear and limbs by ten Berge, D, Brouwer, A, Korving, J, Martin, J F, Meijlink, F

“…Prx1 and Prx2 are closely related paired-class homeobox genes that are expressed in very similar patterns predominantly in mesenchyme. Prx1 loss-of-function…”
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Wnt and FGF signals interact to coordinate growth with cell fate specification during limb development by ten Berge, Derk, Brugmann, Samantha A, Helms, Jill A, Nusse, Roel

“…A fundamental question in developmental biology is how does an undifferentiated field of cells acquire spatial pattern and undergo coordinated differentiation?…”
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Modeling rotavirus infection and antiviral therapy using primary intestinal organoids by Yin, Yuebang, Bijvelds, Marcel, Dang, Wen, Xu, Lei, van der Eijk, Annemiek A., Knipping, Karen, Tuysuz, Nesrin, Dekkers, Johanna F., Wang, Yijin, de Jonge, Jeroen, Sprengers, Dave, van der Laan, Luc J.W., Beekman, Jeffrey M., ten Berge, Derk, Metselaar, Herold J., de Jonge, Hugo, Koopmans, Marion P.G., Peppelenbosch, Maikel P., Pan, Qiuwei

“…•3D-based primary intestinal organoids support the infection of both experimental and patient-derived rotavirus strains.•Rotavirus infection provokes the…”
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WNT/beta-catenin signalling interrupts a senescence-induction cascade in human mesenchymal stem cells that restricts their expansion by Lehmann, Johannes, Narcisi, Roberto, Franceschini, Natasja, Chatzivasileiou, Danai, Boer, Cindy G., Koevoet, Wendy J. L. M., Putavet, Diana, Drabek, Dubravka, van Haperen, Rien, de Keizer, Peter L. J., van Osch, Gerjo J. V. M., ten Berge, Derk

“…Senescence, the irreversible cell cycle arrest of damaged cells, is accompanied by a deleterious pro-inflammatory senescence-associated secretory phenotype…”
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Lipid-mediated Wnt protein stabilization enables serum-free culture of human organ stem cells by Tüysüz, Nesrin, van Bloois, Louis, van den Brink, Stieneke, Begthel, Harry, Verstegen, Monique M. A., Cruz, Luis J., Hui, Lijian, van der Laan, Luc J. W., de Jonge, Jeroen, Vries, Robert, Braakman, Eric, Mastrobattista, Enrico, Cornelissen, Jan J., Clevers, Hans, ten Berge, Derk

“…Wnt signalling proteins are essential for culture of human organ stem cells in organoids, but most Wnt protein formulations are poorly active in serum-free…”
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Integrative biology studies in pluripotent stem cells by Modic, Miha, Cacchiarelli, Davide, ten Berge, Derk

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Dynamics of Proliferative and Quiescent Stem Cells in Liver Homeostasis and Injury by Cao, Wanlu, Chen, Kan, Bolkestein, Michiel, Yin, Yuebang, Verstegen, Monique M.A., Bijvelds, Marcel J.C., Wang, Wenshi, Tuysuz, Nesrin, ten Berge, Derk, Sprengers, Dave, Metselaar, Herold J., van der Laan, Luc J.W., Kwekkeboom, Jaap, Smits, Ron, Peppelenbosch, Maikel P., Pan, Qiuwei

“…Adult liver stem cells are usually maintained in a quiescent/slow-cycling state. However, a proliferative population, marked by leucine-rich repeat-containing…”
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Wnt signaling mediates regional specification in the vertebrate face by Brugmann, Samantha A, Goodnough, L Henry, Gregorieff, Alex, Leucht, Philipp, ten Berge, Derk, Fuerer, Christophe, Clevers, Hans, Nusse, Roel, Helms, Jill A

“…At early stages of development, the faces of vertebrate embryos look remarkably similar, yet within a very short timeframe they adopt species-specific facial…”
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The signaling requirements for mouse embryonic stem cells by Kurek, Dorota, ten Berge, Derk

“…Comment on: ten Berge D, et al. Nat Cell Biol 2011; 13:1070-5. doi:10.1038/ncb2314…”
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