Search Results - "ten, Cate Hugo"

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    Platelets and extra-corporeal membrane oxygenation in adult patients: a systematic review and meta-analysis by Jiritano, Federica, Serraino, Giuseppe Filiberto, ten Cate, Hugo, Fina, Dario, Matteucci, Matteo, Mastroroberto, Pasquale, Lorusso, Roberto

    Published in Intensive care medicine (01-06-2020)
    “…Despite increasing improvement in extracorporeal membrane oxygenation (ECMO) technology and knowledge, thrombocytopenia and impaired platelet function are…”
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    Journal Article
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    The Hemostatic System as a Modulator of Atherosclerosis by Borissoff, Julian Ilcheff, Spronk, Henri M.H, ten Cate, Hugo

    Published in The New England journal of medicine (05-05-2011)
    “…Experimental data suggest that the hemostatic system can accelerate plaque vulnerability to thrombosis in vivo. However, clinical support for these findings…”
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    Clonal hematopoietic mutations linked to platelet traits and the risk of thrombosis or bleeding by Veninga, Alicia, De Simone, Ilaria, Heemskerk, Johan W M, Cate, Hugo Ten, van der Meijden, Paola E J

    Published in Haematologica (Roma) (01-08-2020)
    “…Platelets are key elements in thrombosis, particularly in atherosclerosis-associated arterial thrombosis (atherothrombosis), and hemostasis. Megakaryocytes in…”
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    Thrombin-Fibrin(ogen) Interactions, Host Defense and Risk of Thrombosis by Hulshof, Anne-Marije, Hemker, H Coenraad, Spronk, Henri M H, Henskens, Yvonne M C, Ten Cate, Hugo

    “…Fibrinogen is a well-known risk factor for arterial and venous thrombosis. Its function is not restricted to clot formation, however, as it partakes in a…”
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    Surviving Covid-19 with Heparin? by ten Cate, Hugo

    Published in The New England journal of medicine (26-08-2021)
    “…Patients who are admitted to the hospital with coronavirus disease 2019 (Covid-19) are at high risk for thrombosis, particularly venous thromboembolism (VTE)…”
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    EHA Guidelines on Management of Antithrombotic Treatments in Thrombocytopenic Patients With Cancer by Falanga, Anna, Leader, Avi, Ambaglio, Chiara, Bagoly, Zsuzsa, Castaman, Giancarlo, Elalamy, Ismail, Lecumberri, Ramon, Niessner, Alexander, Pabinger, Ingrid, Szmit, Sebastian, Trinchero, Alice, Ten Cate, Hugo, Rocca, Bianca

    Published in HemaSphere (01-08-2022)
    “…In cancer patients, thrombocytopenia can result from bone marrow infiltration or from anticancer medications and represents an important limitation for the use…”
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    Platelet full length TFPI-α in healthy volunteers is not affected by sex or hormonal use by Winckers, Kristien, Thomassen, Stella, Ten Cate, Hugo, Hackeng, Tilman M

    Published in PloS one (03-02-2017)
    “…Only 10% of plasma TFPIα (TFPI) exists in the full length form, the rest circulates as a C-terminally truncated form. However, blood platelets exclusively…”
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    Platelet Activation Mechanisms and Consequences of Immune Thrombocytopenia by Sun, Siyu, Urbanus, Rolf T, Ten Cate, Hugo, de Groot, Philip G, de Laat, Bas, Heemskerk, Johan W M, Roest, Mark

    Published in Cells (Basel, Switzerland) (01-12-2021)
    “…Autoimmune disorders are often associated with low platelet count or thrombocytopenia. In immune-induced thrombocytopenia (IIT), a common mechanism is…”
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    Targeting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice by Posthuma, Jelle J., Posma, Jens J. N., van Oerle, Rene, Leenders, Peter, van Gorp, Rick H., Jaminon, Armand M. G., Mackman, Nigel, Heitmeier, Stefan, Schurgers, Leon J., ten Cate, Hugo, Spronk, Henri M. H.

    Published in Scientific reports (07-03-2019)
    “…Atherosclerosis is a progressive inflammatory vascular disorder, complicated by plaque rupture and subsequently atherothrombosis. In vitro studies indicate…”
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    Decreased prothrombin conversion and reduced thrombin inactivation explain rebalanced thrombin generation in liver cirrhosis by Kremers, Romy M W, Kleinegris, Marie-Claire, Ninivaggi, Marisa, de Laat, Bas, Ten Cate, Hugo, Koek, Ger H, Wagenvoord, Rob J, Hemker, H Coenraad

    Published in PloS one (04-05-2017)
    “…Impaired coagulation factor synthesis in cirrhosis causes a reduction of most pro- and anticoagulant factors. Cirrhosis patients show no clear bleeding or…”
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    Early atherosclerosis exhibits an enhanced procoagulant state by Borissoff, Julian Ilcheff, Heeneman, Sylvia, Kilinç, Evren, Kassák, Peter, Van Oerle, René, Winckers, Kristien, Govers-Riemslag, José W P, Hamulyák, Karly, Hackeng, Tilman M, Daemen, Mat J A P, ten Cate, Hugo, Spronk, Henri M H

    Published in Circulation (New York, N.Y.) (24-08-2010)
    “…Thrombin generation in vivo may be important in regulating atherosclerotic progression. In the present study, we examined for the first time the activity and…”
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    Misfolded proteins activate factor XII in humans, leading to kallikrein formation without initiating coagulation by Maas, Coen, Govers-Riemslag, José W P, Bouma, Barend, Schiks, Bettina, Hazenberg, Bouke P C, Lokhorst, Henk M, Hammarström, Per, ten Cate, Hugo, de Groot, Philip G, Bouma, Bonno N, Gebbink, Martijn F B G

    Published in The Journal of clinical investigation (01-09-2008)
    “…When blood is exposed to negatively charged surface materials such as glass, an enzymatic cascade known as the contact system becomes activated. This cascade…”
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    Factor XIa and Thrombin Generation Are Elevated in Patients with Acute Coronary Syndrome and Predict Recurrent Cardiovascular Events by Loeffen, Rinske, van Oerle, René, Leers, Mathie P G, Kragten, Johannes A, Crijns, Harry, Spronk, Henri M H, Ten Cate, Hugo

    Published in PloS one (15-07-2016)
    “…In acute coronary syndrome (ACS) cardiac cell damage is preceded by thrombosis. Therefore, plasma coagulation markers may have additional diagnostic relevance…”
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