Search Results - "te Winkel, M. L."
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A randomized trial investigating an exercise program to prevent reduction of bone mineral density and impairment of motor performance during treatment for childhood acute lymphoblastic leukemia
Published in Pediatric Blood & Cancer (15-07-2009)“…Background Reduced bone mineral density (BMD), altered body composition, impaired motor performance and passive ankle dorsiflexion are side effects of acute…”
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NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols
Published in Leukemia (01-12-2010)“…Aberrant activation of the NOTCH1 pathway by inactivating and activating mutations in NOTCH1 or FBXW7 is a frequent phenomenon in T-cell acute lymphoblastic…”
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Germline variation in the MTHFR and MTRR genes determines the nadir of bone density in pediatric acute lymphoblastic leukemia: A prospective study
Published in Bone (New York, N.Y.) (01-03-2011)“…Abstract Background This study aims to identify folate-metabolism-related genetic risk factors for low bone mineral density (BMD) during/after pediatric acute…”
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Genetic and metabolic determinants of methotrexate-induced mucositis in pediatric acute lymphoblastic leukemia
Published in The pharmacogenomics journal (01-06-2015)“…Methotrexate (MTX) is an effective and toxic chemotherapeutic drug in the treatment of pediatric acute lymphoblastic leukemia(ALL). In this prospective study,…”
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Endocrine late sequelae in long-term survivors of childhood non-Hodgkin lymphoma
Published in Annals of oncology (01-06-2012)“…Aim of this study was to investigate the long-term endocrine effects of treatment of childhood non-Hodgkin lymphoma (NHL). A single-center cohort of 84…”
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Posterior reversible encephalopathy syndrome in childhood cancer
Published in Annals of oncology (01-02-2011)“…Posterior reversible encephalopathy syndrome (PRES) is characterized by seizures, headaches, altered mental status, cortical blindness and typical transient…”
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Self-limiting sternal tumors of childhood (SELSTOC)
Published in Pediatric blood & cancer (15-07-2010)“…Background Because a sternal mass is often alarming, it is important to identify the clinical features of benign processes. Procedure Data on clinical…”
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Letter to the editor in response to “Prospective bone ultrasound patterns during childhood acute lymphoblastic leukemia” by Mussa et al
Published in Bone (New York, N.Y.) (01-10-2010)Get full text
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Bone mineral density after childhood cancer in 346 long-term adult survivors of childhood cancer
Published in Osteoporosis international (01-02-2015)“…Summary More than 45 % of long-term childhood cancer survivors (CCS) were diagnosed with osteopenia. Our data suggest that greater awareness for osteopenia is…”
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Childhood paroxysmal nocturnal haemoglobinuria (PNH), a report of 11 cases in the Netherlands
Published in British journal of haematology (01-02-2005)“…Summary Paroxysmal nocturnal haemoglobinuria (PNH) is characterized by intravascular haemolysis, nocturnal haemoglobinuria, thrombotic events, serious…”
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Management and treatment of osteonecrosis in children and adolescents with acute lymphoblastic leukemia
Published in Haematologica (Roma) (01-03-2014)“…There is no consensus regarding how to manage osteonecrosis in pediatric acute lymphoblastic leukemia patients. Therefore, we performed a quality assessment of…”
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The negative impact of being underweight and weight loss on survival of children with acute lymphoblastic leukemia
Published in Haematologica (Roma) (01-01-2015)“…Body mass index and change in body mass index during treatment may influence treatment outcome of pediatric patients with acute lymphoblastic leukemia…”
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Aggravated bone density decline following symptomatic osteonecrosis in children with acute lymphoblastic leukemia
Published in Haematologica (Roma) (01-12-2015)“…Osteonecrosis and decline of bone density are serious side effects during and after treatment of childhood acute lymphoblastic leukemia. It is unknown whether…”
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Impaired dexamethasone-related increase of anticoagulants is associated with the development of osteonecrosis in childhood acute lymphoblastic leukemia
Published in Haematologica (Roma) (01-10-2008)“…Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Childrens Hospital, Rotterdam, The Netherlands Correspondence: Marry M. van den Heuvel-Eibrink,…”
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Pharmacogenetic risk factors for altered bone mineral density and body composition in pediatric acute lymphoblastic leukemia
Published in Haematologica (Roma) (01-05-2010)“…This study investigates pharmacogenetic risk factors for bone mineral (apparent) density (BM(A)D) and body composition in pediatric acute lymphoblastic…”
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NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols : Prognostic effects of NOTCH1 activing mutations in pediatrics T-ALL is treatment dependent
Published in Leukemia (2010)Get full text
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