Search Results - "te Morsche, René H M"

Heterozygosity of ALG9 in Association with Autosomal Dominant Polycystic Liver Disease by Boerrigter, Melissa M, Duijzer, Renée, te Morsche, René H. M, Drenth, Joost P. H

“…α-1,2-mannosyltransferase (ALG9) germline variants are linked to autosomal dominant polycystic kidney disease (ADPKD). Many individuals affected with ADPKD…”
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Loss of heterozygosity is present in SEC63 germline carriers with polycystic liver disease by Janssen, Manoe J, Salomon, Jody, Te Morsche, René H M, Drenth, Joost P H

“…Polycystic liver disease (PCLD) is an autosomal dominant disorder characterised by multiple fluid filled cysts in the liver. This rare disease is caused by…”
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Novel α-1,3-Glucosyltransferase Variants and Their Broad Clinical Polycystic Liver Disease Spectrum by Boerrigter, Melissa M, Te Morsche, René H M, Venselaar, Hanka, Pastoors, Nikki, Geerts, Anja M, Hoorens, Anne, Drenth, Joost P H

“…Protein-truncating variants in α-1,3-glucosyltransferase ( ) are a risk factor for a mild cystic kidney disease phenotype. The association between these…”
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Paroxysmal extreme pain disorder: a molecular lesion of peripheral neurons by Waxman, Stephen G, Choi, Jin-Sung, Boralevi, Franck, Brissaud, Olivier, Sánchez-Martín, Jesús, te Morsche, René H. M, Dib-Hajj, Sulayman D, Drenth, Joost P. H

“…Choi et al . describe the case of a 3 month-old infant who, on the second day of life, had begun to experience painful paroxysmal events starting with tonic…”
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Effect of a specific cyclooxygenase-gene polymorphism (A-842G/C50T) on the occurrence of peptic ulcer hemorrhage by VAN OIJEN, Martijn G. H, LAHEIJ, Robert J. F, KOETSIER, Marjolein, DE KLEINE, Evelien, TE MORSCHE, René H. M, VAN KERKHOVEN, Lieke A. S, JANSEN, Jan B. M. J, DRENTH, Joost P. H

“…Cyclooxygenases (COX) catalyze the conversion of arachidonic acid to prostaglandins (PGs). COX-inhibiting drugs, such as nonsteroidal anti-inflammatory drugs…”
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Whole-exome sequencing reveals LRP5 mutations and canonical Wnt signaling associated with hepatic cystogenesis by Cnossen, Wybrich R., te Morsche, René H. M., Hoischen, Alexander, Gilissen, Christian, Chrispijn, Melissa, Venselaar, Hanka, Mehdi, Soufi, Bergmann, Carsten, Veltman, Joris A., Drenth, Joost P. H.

“…Polycystic livers are seen in the rare inherited disorder isolated polycystic liver disease (PCLD) and are recognized as the most common extrarenal…”
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Novel GANAB variants associated with polycystic liver disease by van de Laarschot, Liyanne F M, Te Morsche, René H M, Hoischen, Alexander, Venselaar, Hanka, Roelofs, Hennie M, Cnossen, Wybrich R, Banales, Jesus M, Roepman, Ronald, Drenth, Joost P H

“…Polycystic liver disease (PLD) is an inherited disorder characterized by numerous cysts in the liver. Autosomal dominant polycystic kidney and liver disease…”
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Short mucin 6 alleles are associated with H pylori infection by Nguyen, Thai V, Janssen, Jr, Marcel, Gritters, Paulien, te Morsche, René H M, Drenth, Joost P H, van Asten, Henri, Laheij, Robert J F, Jansen, Jan B M J

“…AIM： To investigate the relationship between mucin 6 （MUC6） VNTR length and Hpylori infection. METHODS： Blood samples were collected from patients visiting the…”
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Severe Polycystic Liver Disease Is Not Caused by Large Deletions of the PRKCSH Gene by Cnossen, Wybrich R., Maurits, Jake S.F., Salomon, Jody, te Morsche, René H.M., Waanders, Esmé, Drenth, Joost P. H.

“…Background Isolated polycystic liver disease (ADPLD) is an autosomal dominant Mendelian disorder. Heterozygous PRKCSH (where PRKCSH is protein kinase C…”
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LRP5 variants may contribute to ADPKD by Cnossen, Wybrich R, te Morsche, René H M, Hoischen, Alexander, Gilissen, Christian, Venselaar, Hanka, Mehdi, Soufi, Bergmann, Carsten, Losekoot, Monique, Breuning, Martijn H, Peters, Dorien J M, Veltman, Joris A, Drenth, Joost P H

“…Mutations in Polycystic Kidney Disease proteins (PKD1 or PKD2) are causative for autosomal dominant polycystic kidney disease (ADPKD). However, a small subset…”
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Cysts of PRKCSH mutated polycystic liver disease patients lack hepatocystin but express Sec63p by Waanders, Esmé, Croes, Huib J. E., Maass, Cathy N., te Morsche, René H. M., van Geffen, Hendrikus J. A. A., van Krieken, J. Han J. M., Fransen, Jack A. M., Drenth, Joost P. H.

“…Polycystic liver disease (PCLD) is an inherited disorder caused by mutations in either PRKCSH (hepatocystin) or SEC63 (Sec63p). However, expression patterns of…”
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Influence of Curcumin, Quercetin, and Eicosapentaenoic Acid on the Expression of Phase II Detoxification Enzymes in the Intestinal Cell Lines HT-29, Caco-2, HuTu 80, and LT97 by Odenthal, Julia, van Heumen, Bjorn W. H, Roelofs, Hennie M. J, te Morsche, Rene H. M, Marian, Brigitte, Nagengast, Fokko M, Peters, Wilbert H. M

“…Curcumin, quercetin, and eicosapentaenoic acid (EPA) are 3 natural compounds with the capacity to reduce adenoma burden in patients with familial adenomatous…”
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Cyclooxygenase-2 polymorphisms and the risk of esophageal adeno- or squamous cell carcinoma by Kristinsson, Jón O, van Westerveld, Paul, te Morsche, Rene H M, Roelofs, Hennie M J, Wobbes, T, Witteman, Ben J M, Tan, Adriaan C I T L, van Oijen, Martijn G H, Jansen, Jan B M J, Peters, Wilbert H M

“…AIM： TO determine whether -1195 A→G and/or -765 G→C polymorphisms in Cyclooxygenase-2 CCOX-2） may have a risk modifying effect on the development of esophageal…”
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The functional -765G→C polymorphism of the COX-2 gene may reduce the risk of developing crohn's disease by de Vries, Hilbert S, te Morsche, Rene H M, van Oijen, Martijn G H, Nagtegaal, Iris D, Peters, Wilbert H M, de Jong, Dirk J

“…Cyclooxygenase-2 (COX-2) is a key enzyme involved in the conversion of arachidonic acid into prostaglandins. COX-2 is mainly induced at sites of inflammation…”
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Infliximab Exerts No Direct Hepatotoxic Effect on HepG2 Cells In Vitro by de Vries, Hilbert S., de Heij, Tineke, Roelofs, Henie M. J., te Morsche, Rene H. M., Peters, Wilbert H. M., de Jong, Dirk J.

“…Background Infliximab-induced hepatotoxicity is reported in several case studies involving patients with inflammatory bowel disease (IBD) and a direct…”
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Common variants in glyoxalase I do not increase chronic pancreatitis risk by Kaune, Tom, Hollenbach, Marcus, Keil, Bettina, Chen, Jian-Min, Masson, Emmanuelle, Becker, Carla, Damm, Marko, Ruffert, Claudia, Grützmann, Robert, Hoffmeister, Albrecht, Te Morsche, Rene H M, Cavestro, Giulia Martina, Zuppardo, Raffaella Alessia, Saftoiu, Adrian, Malecka-Panas, Ewa, Głuszek, Stanislaw, Bugert, Peter, Lerch, Markus M, Weiss, Frank Ulrich, Zou, Wen-Bin, Liao, Zhuan, Hegyi, Peter, Drenth, Joost Ph, Riedel, Jan, Férec, Claude, Scholz, Markus, Kirsten, Holger, Tóth, Andrea, Ewers, Maren, Witt, Heiko, Griesmann, Heidi, Michl, Patrick, Rosendahl, Jonas

“…Chronic pancreatitis (CP) may be caused by oxidative stress. An important source of reactive oxygen species (ROS) is the methylglyoxal-derived formation of…”
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Over-expression of COX-2 mRNA in colorectal cancer by Roelofs, Hennie M J, Te Morsche, Rene H M, van Heumen, Bjorn W H, Nagengast, Fokko M, Peters, Wilbert H M

“…Cyclooxygenase-2 (COX-2, PTGS2) is an enzyme involved in the synthesis of prostaglandins and thromboxanes, which are regulators of biologic processes such as…”
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Celecoxib and tauro-ursodeoxycholic acid co-treatment inhibits cell growth in familial adenomatous polyposis derived LT97 colon adenoma cells by van Heumen, Bjorn W.H., Roelofs, Hennie M.J., te Morsche, René H.M., Marian, Brigitte, Nagengast, Fokko M., Peters, Wilbert H.M.

“…Chemoprevention would be a desirable strategy to avoid duodenectomy in patients with familial adenomatous polyposis (FAP) suffering from duodenal adenomatosis…”
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COX-2 polymorphisms and the risk for head and neck cancer in white patients by Peters, Wilbert H. M., Lacko, Martin, te Morsche, Rene H. M., Voogd, Adri C., Oude Ophuis, Michael B., Manni, Johannes J.

“…Background. Cyclooxygenase‐2 (COX‐2) is an enzyme involved in the synthesis of prostaglandins and thromboxanes, which are regulators of processes such as…”
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Functional profiles of SCN9A variants in dorsal root ganglion neurons and superior cervical ganglion neurons correlate with autonomic symptoms in small fibre neuropathy by CHONGYANG HAN, HOEIJMAKERS, Janneke G. J, WAXMAN, Stephen G, SHUJUN LIU, GERRITS, Monique M, TE MORSCHE, Rene H. M, LAURIA, Giuseppe, DIB-HAJJ, Sulayman D, DRENTH, Joost P. H, FABER, Catharina G, MERKIES, Ingemar S. J

“…Patients with small fibre neuropathy typically manifest pain in distal extremities and severe autonomic dysfunction. However, occasionally patients present…”
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