Search Results - "st, Alexandra H"

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  1. 1

    Macrodomain-containing proteins: regulating new intracellular functions of mono(ADP-ribosyl)ation by Feijs, Karla L. H., Forst, Alexandra H., Verheugd, Patricia, Lüscher, Bernhard

    Published in Nature reviews. Molecular cell biology (01-07-2013)
    “…The function and regulation of poly(ADP-ribosyl)ation is partially understood. By contrast, little is known about intracellular mono(ADP-ribosyl)ation…”
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    Journal Article
  2. 2

    Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases by Rosenthal, Florian, Feijs, Karla L H, Frugier, Emilie, Bonalli, Mario, Forst, Alexandra H, Imhof, Ralph, Winkler, Hans C, Fischer, David, Caflisch, Amedeo, Hassa, Paul O, Lüscher, Bernhard, Hottiger, Michael O

    Published in Nature structural & molecular biology (01-04-2013)
    “…ADP-ribosylation is an important post-translational protein modification, yet enzymes capable of removing the protein-proximal ADP-ribose were unknown. Human…”
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  3. 3

    Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10 by Verheugd, Patricia, Forst, Alexandra H., Milke, Larissa, Herzog, Nicolas, Feijs, Karla L.H., Kremmer, Elisabeth, Kleine, Henning, Lüscher, Bernhard

    Published in Nature communications (2013)
    “…Adenosine diphosphate-ribosylation is a post-translational modification mediated by intracellular and membrane-associated extracellular enzymes and many…”
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    Journal Article
  4. 4

    ARTD10 substrate identification on protein microarrays: regulation of GSK3β by mono-ADP-ribosylation by Feijs, Karla Lh, Kleine, Henning, Braczynski, Anne, Forst, Alexandra H, Herzog, Nicolas, Verheugd, Patricia, Linzen, Ulrike, Kremmer, Elisabeth, Lüscher, Bernhard

    Published in Cell communication and signaling (19-01-2013)
    “…Although ADP-ribosylation has been described five decades ago, only recently a distinction has been made between eukaryotic intracellular poly- and…”
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    Journal Article
  5. 5

    Recognition of Mono-ADP-Ribosylated ARTD10 Substrates by ARTD8 Macrodomains by Forst, Alexandra H., Karlberg, Tobias, Herzog, Nicolas, Thorsell, Ann-Gerd, Gross, Annika, Feijs, Karla L.H., Verheugd, Patricia, Kursula, Petri, Nijmeijer, Bianca, Kremmer, Elisabeth, Kleine, Henning, Ladurner, Andreas G., Schüler, Herwig, Lüscher, Bernhard

    Published in Structure (London) (05-03-2013)
    “…ADP-ribosyltransferases (ARTs) catalyze the transfer of ADP-ribose from NAD+ onto substrates. Some ARTs generate in an iterative process ADP-ribose polymers…”
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  6. 6

    The interaction of MYC with the trithorax protein ASH2L promotes gene transcription by regulating H3K27 modification by Ullius, Andrea, Lüscher-Firzlaff, Juliane, Costa, Ivan G, Walsemann, Gesa, Forst, Alexandra H, Gusmao, Eduardo G, Kapelle, Karsten, Kleine, Henning, Kremmer, Elisabeth, Vervoorts, Jörg, Lüscher, Bernhard

    Published in Nucleic acids research (17-06-2014)
    “…The appropriate expression of the roughly 30,000 human genes requires multiple layers of control. The oncoprotein MYC, a transcriptional regulator, contributes…”
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  7. 7

    Caspase‐dependent cleavage of the mono‐ADP‐ribosyltransferase ARTD10 interferes with its pro‐apoptotic function by Herzog, Nicolas, Hartkamp, Jörg D. H., Verheugd, Patricia, Treude, Fabian, Forst, Alexandra H., Feijs, Karla L. H., Lippok, Barbara E., Kremmer, Elisabeth, Kleine, Henning, Lüscher, Bernhard

    Published in The FEBS journal (01-03-2013)
    “…ADP‐ribosylation is a post‐translational modification that regulates various physiological processes, including DNA damage repair, gene transcription and…”
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  8. 8
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  10. 10

    ARTD10 substrate identification on protein microarrays: regulation of GSK3[beta] by mono-ADP-ribosylation by Feijs, Karla LH, Kleine, Henning, Braczynski, Anne, Forst, Alexandra H, Herzog, Nicolas, Verheugd, Patricia, Linzen, Ulrike, Kremmer, Elisabeth, Lüscher, Bernhard

    Published in Cell communication and signaling (19-01-2013)
    “…Although ADP-ribosylation has been described five decades ago, only recently a distinction has been made between eukaryotic intracellular poly- and…”
    Get full text
    Journal Article
  11. 11

    Regulation of NF-[kappa]B signalling by the mono-ADP-ribosyltransferase ARTD10 by Verheugd, Patricia, st, Alexandra H, Milke, Larissa, Herzog, Nicolas, Feijs, Karla Lh, Kremmer, Elisabeth, Kleine, Henning, Lüscher, Bernhard

    Published in Nature communications (01-04-2013)
    “…Adenosine diphosphate-ribosylation is a post-translational modification mediated by intracellular and membrane-associated extracellular enzymes and many…”
    Get full text
    Journal Article