Search Results - "mesuraca, maria"

Zinc Finger 521 Modulates the Nrf2-Notch Signaling Pathway in Human Ovarian Carcinoma by Scicchitano, Stefania, Faniello, Maria Concetta, Mesuraca, Maria

“…The human zinc finger protein 521 (ZNF521) is a co-transcriptional factor with multiple recognized regulatory functions in a range of normal, cancer and stem…”
Get full text

Cellular and Biochemical Characterization of Mesenchymal Stem Cells from Killian Nasal Polyp by Mesuraca, Maria, Nisticò, Clelia, Lombardo, Nicola, Piazzetta, Giovanna Lucia, Lobello, Nadia, Chiarella, Emanuela

“…Killian’s (antrochoanal) polyp is a unilateral nasal polypoid lesion of the maxillary sinus especially affecting children and young adults with unilateral…”
Get full text

Regulatory Role of microRNAs Targeting the Transcription Co-Factor ZNF521 in Normal Tissues and Cancers by Chiarella, Emanuela, Aloisio, Annamaria, Scicchitano, Stefania, Bond, Heather Mandy, Mesuraca, Maria

“…Powerful bioinformatics tools have provided a wealth of novel miRNA–transcription factor networks crucial in controlling gene regulation. In this review, we…”
Get full text

Nasal Polyposis: Insights in Epithelial-Mesenchymal Transition and Differentiation of Polyp Mesenchymal Stem Cells by Chiarella, Emanuela, Lombardo, Nicola, Lobello, Nadia, Aloisio, Annamaria, Aragona, Teodoro, Pelaia, Corrado, Scicchitano, Stefania, Bond, Heather Mandy, Mesuraca, Maria

“…Chronic rhinosinusitis is a common inflammatory disease of paranasal sinuses, which causes rhinorrhea, nasal congestion, and hyposmia. The genetic…”
Get full text

Lipid Droplet Biosynthesis Impairment through DGAT2 Inhibition Sensitizes MCF7 Breast Cancer Cells to Radiation by Nisticò, Clelia, Pagliari, Francesca, Chiarella, Emanuela, Fernandes Guerreiro, Joana, Marafioti, Maria Grazia, Aversa, Ilenia, Genard, Geraldine, Hanley, Rachel, Garcia-Calderón, Daniel, Bond, Heather Mandy, Mesuraca, Maria, Tirinato, Luca, Spadea, Maria Francesca, Seco, Joao Carlos

“…Breast cancer is the most frequent cancer in women worldwide and late diagnosis often adversely affects the prognosis of the disease. Radiotherapy is commonly…”
Get full text

A Review of Novel Strategies for Human Periodontal Ligament Stem Cell Ex Vivo Expansion: Are They an Evidence-Based Promise for Regenerative Periodontal Therapy? by Di Vito, Anna, Bria, Jessica, Antonelli, Alessandro, Mesuraca, Maria, Barni, Tullio, Giudice, Amerigo, Chiarella, Emanuela

“…Periodontitis is a gingiva disease sustained by microbially associated and host-mediated inflammation that results in the loss of the connective periodontal…”
Get full text

Deficit in Adipose Differentiation in Mesenchymal Stem Cells Derived from Chronic Rhinosinusitis Nasal Polyps Compared to Nasal Mucosal Tissue by Chiarella, Emanuela, Lombardo, Nicola, Lobello, Nadia, Piazzetta, Giovanna Lucia, Morrone, Helen Linda, Mesuraca, Maria, Bond, Heather Mandy

“…Chronic rhinosinusitis of the nasal mucosa is an inflammatory disease of paranasal sinuses, which causes rhinorrhea, nasal congestion, and hyposmia, and in…”
Get full text

Enhanced ZNF521 expression induces an aggressive phenotype in human ovarian carcinoma cell lines by Scicchitano, Stefania, Montalcini, Ylenia, Lucchino, Valeria, Melocchi, Valentina, Gigantino, Valerio, Chiarella, Emanuela, Bianchi, Fabrizio, Weisz, Alessandro, Mesuraca, Maria

“…Epithelial ovarian carcinoma (EOC) is the most lethal gynecological tumor, that almost inevitably relapses and develops chemo-resistance. A better…”
Get full text

Editorial to the Special Issue "Recent Advances in Biochemical Mechanisms of Acute Myeloid Leukemia" by Mesuraca, Maria, Nisticò, Clelia, Chiarella, Emanuela

“…Acute myeloid leukemia (AML) is a clonal malignant disorder of myeloid progenitor cells characterized by uncontrolled proliferation, dysregulation in the…”
Get full text

ZNF521 Enhances MLL-AF9-Dependent Hematopoietic Stem Cell Transformation in Acute Myeloid Leukemias by Altering the Gene Expression Landscape by Chiarella, Emanuela, Aloisio, Annamaria, Scicchitano, Stefania, Todoerti, Katia, Cosentino, Emanuela G., Lico, Daniela, Neri, Antonino, Amodio, Nicola, Bond, Heather Mandy, Mesuraca, Maria

“…Leukemias derived from the MLL-AF9 rearrangement rely on dysfunctional transcriptional networks. ZNF521, a transcription co-factor implicated in the control of…”
Get full text

Targeting of Mevalonate-Isoprenoid Pathway in Acute Myeloid Leukemia Cells by Bisphosphonate Drugs by Chiarella, Emanuela, Nisticò, Clelia, Di Vito, Anna, Morrone, Helen Linda, Mesuraca, Maria

“…Metabolic reprogramming represents a hallmark of tumorigenesis to sustain survival in harsh conditions, rapid growth and metastasis in order to resist to…”
Get full text

ZNF521 Represses Osteoblastic Differentiation in Human Adipose-Derived Stem Cells by Chiarella, Emanuela, Aloisio, Annamaria, Scicchitano, Stefania, Lucchino, Valeria, Montalcini, Ylenia, Galasso, Olimpio, Greco, Manfredi, Gasparini, Giorgio, Mesuraca, Maria, Bond, Heather M, Morrone, Giovanni

“…Human adipose-derived stem cells (hADSCs) are multipotent mesenchymal cells that can differentiate into adipocytes, chondrocytes, and osteocytes. During…”
Get full text

ZNF423: A New Player in Estrogen Receptor-Positive Breast Cancer by Bond, Heather M, Scicchitano, Stefania, Chiarella, Emanuela, Amodio, Nicola, Lucchino, Valeria, Aloisio, Annamaria, Montalcini, Ylenia, Mesuraca, Maria, Morrone, Giovanni

“…Preventive therapy can target hormone-responsive breast cancer (BC) by treatment with selective estrogen receptor modulators (SERMs) and reduce the incidence…”
Get full text

Turning Stem Cells Bad: Generation of Clinically Relevant Models of Human Acute Myeloid Leukemia through Gene Delivery- or Genome Editing-Based Approaches by Mesuraca, Maria, Amodio, Nicola, Chiarella, Emanuela, Scicchitano, Stefania, Aloisio, Annamaria, Codispoti, Bruna, Lucchino, Valeria, Montalcini, Ylenia, Bond, Heather M, Morrone, Giovanni

“…Acute myeloid leukemia (AML), the most common acute leukemia in the adult, is believed to arise as a consequence of multiple molecular events that confer on…”
Get full text

GPER1 Activation Exerts Anti-Tumor Activity in Multiple Myeloma by Gallo Cantafio, Maria Eugenia, Torcasio, Roberta, Scionti, Francesca, Mesuraca, Maria, Ronchetti, Domenica, Pistoni, Mariaelena, Bellizzi, Dina, Passarino, Giuseppe, Morelli, Eugenio, Neri, Antonino, Viglietto, Giuseppe, Amodio, Nicola

“…G protein-coupled estrogen receptor 1 (GPER1) activation is emerging as a promising therapeutic strategy against several cancer types. While GPER targeting has…”
Get full text

Zoledronic acid inhibits the growth of leukemic MLL-AF9 transformed hematopoietic cells by Chiarella, Emanuela, Codispoti, Bruna, Aloisio, Annamaria, Cosentino, Emanuela G., Scicchitano, Stefania, Montalcini, Ylenia, Lico, Daniela, Morrone, Giovanni, Mesuraca, Maria, Bond, Heather M.

“…A leukemic in vitro model produced by transducing Cord Blood derived-hematopoietic CD34+ cells with the MLL-AF9 translocation resulting in the oncogenic fusion…”
Get full text

Zinc finger protein 521 antagonizes early B-cell factor 1 and modulates the B-lymphoid differentiation of primary hematopoietic progenitors by Mega, Tiziana, Lupia, Michela, Amodio, Nicola, Horton, Sarah J., Mesuraca, Maria, Pelaggi, Daniela, Agosti, Valter, Grieco, Michele, Chiarella, Emanuela, Spina, Raffaella, Moore, Malcolm A.S., Schuringa, Jan Jacob, Bond, Heather M., Morrone, Giovanni

“…Zinc finger protein 521 (EHZF/ZNF521) is a multi-functional transcription co-factor containing 30 zinc fingers and an amino-terminal motif that binds to the…”
Get full text

UMG Lenti: novel lentiviral vectors for efficient transgene- and reporter gene expression in human early hematopoietic progenitors by Chiarella, Emanuela, Carrà, Giovanna, Scicchitano, Stefania, Codispoti, Bruna, Mega, Tiziana, Lupia, Michela, Pelaggi, Daniela, Marafioti, Maria G, Aloisio, Annamaria, Giordano, Marco, Nappo, Giovanna, Spoleti, Cristina B, Grillone, Teresa, Giovannone, Emilia D, Spina, Raffaella, Bernaudo, Francesca, Moore, Malcolm A S, Bond, Heather M, Mesuraca, Maria, Morrone, Giovanni

“…Lentiviral vectors are widely used to investigate the biological properties of regulatory proteins and/or of leukaemia-associated oncogenes by stably enforcing…”
Get full text

Expression Profiling and Functional Implications of a Set of Zinc Finger Proteins, ZNF423, ZNF470, ZNF521, and ZNF780B, in Primary Osteoarthritic Articular Chondrocytes by Gasparini, Giorgio, Bond, Heather M., Vatrinet, Renaud, Scicchitano, Stefania, Chiarella, Emanuela, Guido, Leonardo, Galasso, Olimpio, Mesuraca, Maria, Morrone, Giovanni

“…Articular chondrocytes are responsible for the maintenance of healthy articulations; indeed, dysregulation of their functions, including the production of…”
Get full text

Early hematopoietic zinc finger protein—zinc finger protein 521: A candidate regulator of diverse immature cells by Bond, Heather M., Mesuraca, Maria, Amodio, Nicola, Mega, Tiziana, Agosti, Valter, Fanello, Delia, Pelaggi, Daniela, Bullinger, Lars, Grieco, Michele, Moore, Malcolm A.S., Venuta, Salvatore, Morrone, Giovanni

“…The early hematopoietic zinc finger protein/zinc finger protein 521 (EHZF/ZNF521) is a recently identified, 1131 amino-acid-long nuclear factor that contains…”
Get full text