Search Results - "man, Jay"
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Two- and three-body contacts in the unitary Bose gas
Published in Science (American Association for the Advancement of Science) (27-01-2017)“…In many-body systems governed by pairwise contact interactions, a wide range of observables is linked by a single parameter, the two-body contact, which…”
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Connecting Berezinskii-Kosterlitz-Thouless and BEC Phase Transitions by Tuning Interactions in a Trapped Gas
Published in Physical review letters (26-06-2015)Get full text
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Connecting Berezinskii-Kosterlitz-Thouless and BEC Phase Transitions by Tuning Interactions in a Trapped Gas
Published in Physical review letters (26-06-2015)“…We study the critical point for the emergence of coherence in a harmonically trapped two-dimensional Bose gas with tunable interactions. Over a wide range of…”
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Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
Published in Nature reviews. Drug discovery (01-09-2021)“…Oxidative stress is a component of many diseases, including atherosclerosis, chronic obstructive pulmonary disease, Alzheimer disease and cancer. Although…”
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Redox signaling: An evolution from free radicals to aging
Published in Free radical biology & medicine (01-08-2016)“…Redox biology has evolved from studies of the pathology that involves oxidants to an understanding of how oxidants participate in normal as well as aberrant…”
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Beyond repression of Nrf2: An update on Keap1
Published in Free radical biology & medicine (01-09-2020)“…Nrf2 (NFE2L2 – nuclear factor (erythroid-derived 2)-like 2) is a transcription factor, which is repressed by interaction with a redox-sensitive protein Keap1…”
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An overview of mechanisms of redox signaling
Published in Journal of molecular and cellular cardiology (01-08-2014)“…Abstract A principal characteristic of redox signaling is that it involves an oxidation–reduction reaction or covalent adduct formation between the sensor…”
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A critical review of assays for hazardous components of air pollution
Published in Free radical biology & medicine (01-03-2018)“…Increased mortality and diverse morbidities are globally associated with exposure to ambient air pollution (AAP), cigarette smoke (CS), and household air…”
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Oxidative stress response and Nrf2 signaling in aging
Published in Free radical biology & medicine (01-11-2015)“…Increasing oxidative stress, a major characteristic of aging, has been implicated in a variety of age-related pathologies. In aging, oxidant production from…”
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4-hydroxynonenal-mediated signaling and aging
Published in Free radical biology & medicine (01-10-2017)“…4-Hydroxy-2-nonenal (HNE), one of the major α, β-unsaturated aldehydes produced during lipid peroxidation, is a potent messenger in mediating signaling…”
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On "Biological effects of the superoxide radical" by Irwin Fridovich
Published in Archives of biochemistry and biophysics (15-09-2022)“…Irwin Fridovich, the discoverer of superoxide dismutase, took the opportunity in this invited paper to address the important question, “Can the superoxide…”
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Signaling by 4-hydroxy-2-nonenal: Exposure protocols, target selectivity and degradation
Published in Archives of biochemistry and biophysics (01-03-2017)“…4-hydroxy-2-nonenal (HNE), a major non-saturated aldehyde product of lipid peroxidation, has been extensively studied as a signaling messenger. In these…”
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What is the concentration of hydrogen peroxide in blood and plasma?
Published in Archives of biochemistry and biophysics (01-08-2016)“…The concentration of hydrogen peroxide (H2O2) in blood and plasma is a measurement that has often been made, but the absolute values remain unsettled due the…”
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Redox homeostasis: The Golden Mean of healthy living
Published in Redox biology (01-08-2016)“…The notion that electrophiles serve as messengers in cell signaling is now widely accepted. Nonetheless, major issues restrain acceptance of redox homeostasis…”
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Signaling Functions of Reactive Oxygen Species
Published in Biochemistry (Easton) (09-02-2010)“…We review signaling by reactive oxygen species, which is emerging as a major physiological process. However, among the reactive oxygen species, H2O2 best…”
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Reactive oxygen species and α,β-unsaturated aldehydes as second messengers in signal transduction
Published in Annals of the New York Academy of Sciences (01-08-2010)“…Signaling by H2O2, α,β‐unsaturated aldehydes, such as 4‐hydroxy‐2‐nonenal (HNE) and related chemical species, is thought to differ from signaling by other…”
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Glutathione: Overview of its protective roles, measurement, and biosynthesis
Published in Molecular aspects of medicine (01-02-2009)“…This review is the introduction to a special issue concerning, glutathione (GSH), the most abundant low molecular weight thiol compound synthesized in cells…”
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Glutathione – From antioxidant to post-translational modifier
Published in Archives of biochemistry and biophysics (01-04-2016)“…Helmut Sies is one of the leading investigators in the multiple roles of glutathione (GSH) in biology. He has pioneered work on the role of GSH in preventing…”
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Author Correction: Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
Published in Nature reviews. Drug discovery (01-08-2021)Get full text
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Glutathione synthesis and its role in redox signaling
Published in Seminars in cell & developmental biology (01-09-2012)“…► Glutathione (GSH) is the most abundant antioxidant and a major detoxification agent in cells. ► Glutamate cysteine ligase, which catalyzes the first step in…”
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