Search Results - "le Marec, Fabien"
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Incidence and Risk Factors for Severe Bacterial Infections in People Living with HIV. ANRS CO3 Aquitaine Cohort, 2000-2012
Published in PloS one (06-04-2016)“…Severe non-AIDS bacterial infections (SBI) are the leading cause of hospital admissions among people living with HIV (PLHIV) in industrialized countries. We…”
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Safety and immunogenicity of the live attenuated intranasal pertussis vaccine BPZE1: a phase 1b, double-blind, randomised, placebo-controlled dose-escalation study
Published in The Lancet infectious diseases (01-11-2020)“…Long-term protection and herd immunity induced by existing pertussis vaccines are imperfect, and a need therefore exists to develop new pertussis vaccines…”
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Emulating a trial of joint dynamic strategies: An application to monitoring and treatment of HIV‐positive individuals
Published in Statistics in medicine (15-06-2019)“…Decisions about when to start or switch a therapy often depend on the frequency with which individuals are monitored or tested. For example, the optimal time…”
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Assessing the psychometric properties of the French WHOQOL-HIV BREF within the ANRS CO3 Aquitaine Cohort's QuAliV ancillary study
Published in Health and quality of life outcomes (10-07-2020)“…Antiretroviral therapy has prolonged the lives of those with human immunodeficiency virus (HIV), but the effects of chronic infection on their health-related…”
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Protease inhibitors exposure is not related to lung cancer risk in HIV smoker patients: a nested case-control study
Published in AIDS (London) (01-06-2015)“…We aimed at assessing in persons living with HIV with a smoking history an association between lung cancer risk and protease inhibitors exposure, especially…”
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A Low Level of Darunavir Resistance–Associated Mutation Emergence in Patients With Virological Failure During Long-term Use of Darunavir in People With HIV. The ANRS CO3 Aquitaine Cohort
Published in Open forum infectious diseases (01-12-2020)“…Abstract Background Ritonavir-boosted darunavir (DRV/r) is a protease inhibitor (PI) indicated for the treatment of naïve and pretreated HIV-infected patients…”
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Switch to Rilpivirine/Emtricitabine/Tenofovir Single-Tablet Regimen of Human Immunodeficiency Virus-1 RNA-Suppressed Patients, Agence Nationale de Recherches sur le SIDA et les Hépatites Virales CO3 Aquitaine Cohort, 2012-2014
Published in Open forum infectious diseases (01-01-2015)“…Background. The purpose of this study was to assess the efficacy and tolerability of combined antiretroviral therapy (cART) in human immunodeficiency virus…”
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Incidence of lung and HPV-associated malignancies in HIV-infected patients
Published in AIDS (London) (17-12-2021)Get full text
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Incidence of lung and human papilloma virus-associated malignancies in HIV-infected patients
Published in AIDS (London) (01-04-2022)“…Cancers represent one of the leading cause of mortality/morbidity in patients with HIV (PWH) in industrialized countries. The objective of our study was to…”
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Long-term follow-up of HIV-1 multi-drug-resistant treatment-experienced participants treated with etravirine, raltegravir and boosted darunavir: towards drug-reduced regimen? ANRS CO3 Aquitaine Cohort 2007–2018
Published in International journal of antimicrobial agents (01-01-2023)“…•The TRIO regimen (raltegravir, etravirine and darunavir/ritonavir in combination) showed high efficacy and safety against virological failure in…”
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Statin use and risk of severe bacterial infection in a population living with HIV: prospective cohort study of the ANRS CO3 Aquitaine Cohort 2000–2018
Published in Clinical microbiology and infection (01-09-2021)“…Bacterial infections remain one of the main causes of morbidity and death in people living with HIV (PLHIV) in the most recent years. Several studies have…”
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Cohort Profile: International Collaboration on Hepatitis C Elimination in HIV Cohorts (InCHEHC)
Published in International journal of epidemiology (01-02-2024)Get full text
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Assessing the psychometric properties of the French WHOQOL-HIV BREF within the ANRS CO3 Aquitaine Cohort's QuAliV ancillary study: Health Qual Life Outcomes
Published in Health and quality of life outcomes (2020)“…BackgroundAntiretroviral therapy has prolonged the lives of those with human immunodeficiency virus (HIV), but the effects of chronic infection on their…”
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Incidence of sexually transmitted infections during pre-exposure prophylaxis for HIV: a worrying outcome at 2 years
Published in Sexually transmitted infections (01-11-2019)Get more information
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Association of immune-activation and senescence markers with non-AIDS-defining comorbidities in HIV-suppressed patients
Published in AIDS (London) (23-10-2015)“…We studied the link between T-cell activation, differentiation and senescence phenotypes and non-AIDS-related comorbidities in HIV-suppressed patients…”
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Incidence and Risk Factors for Thoracic Spine Pain in the Working Population: The French Pays de la Loire Study
Published in Arthritis care & research (2010) (01-11-2014)“…Objective To examine the incidence and risk factors for incident thoracic spine pain (TSP) in workers representative of a French region's working population…”
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Serum suppression of tumorigenicity 2 level is an independent predictor of all-cause mortality in HIV-infected patients
Published in AIDS (London) (13-11-2017)“…To evaluate the predictive value of soluble suppression of tumorigenicity 2 (sST2), a decoy receptor of IL-33 involved in several inflammatory and immune…”
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Serum ST2 level is an independent predictor of all-cause mortality in HIV-infected patients. Aquitaine Cohort, France
Published in AIDS (London) (28-08-2017)“…OBJECTIVE:To evaluate the predictive value of Soluble Suppression of Tumorigenicity 2 (sST2), a decoy receptor of IL-33 involved in several inflammatory and…”
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Changes in incidence of hepatitis C virus reinfection and access to direct-acting antiviral therapies in people with HIV from six countries, 2010–19: an analysis of data from a consortium of prospective cohort studies
Published in The lancet HIV (01-02-2024)“…Reinfection after successful treatment with direct-acting antivirals is hypothesised to undermine efforts to eliminate hepatitis C virus (HCV) infection among…”
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Statistical strategies for relating metabolomics and proteomics data: a real case study in nutrition research area
Published in Metabolomics (01-12-2012)“…The current investigations were carried out in the context of a nutritional case study aiming at assessing the postnatal impact of maternal dietary protein…”
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