Search Results - "le Bouc, Yves"

Evaluation of IGF1/IGFBP3 Molar Ratio as an Effective Tool for Assessing the Safety of Growth Hormone Therapy in Small-for-gestational-age, Growth Hormone-Deficient and Prader-Willi Children by Gaddas, Meriem, Périn, Laurence, Le Bouc, Yves

“…IGF1 concentration is the most widely used parameter for the monitoring and therapeutic adaptation of recombinant human growth hormone (rGH) treatment…”
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Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanism by Kappeler, Laurent, De Magalhaes Filho, Carlos, Dupont, Joëlle, Leneuve, Patricia, Cervera, Pascale, Périn, Laurence, Loudes, Catherine, Blaise, Annick, Klein, Rüdiger, Epelbaum, Jacques, Le Bouc, Yves, Holzenberger, Martin

“…Mutations that decrease insulin-like growth factor (IGF) and growth hormone signaling limit body size and prolong lifespan in mice. In vertebrates, these…”
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Cortisol and Aldosterone Responses to Hypoglycemia and Na Depletion in Women With Non-Classic 21-Hydroxylase Deficiency by Kamenický, Peter, Blanchard, Anne, Lamaziere, Antonin, Piedvache, Céline, Donadille, Bruno, Duranteau, Lise, Bry, Hélène, Gautier, Jean-François, Salenave, Sylvie, Raffin-Sanson, Marie-Laure, Genc, Seray, Pietri, Laurence, Christin-Maitre, Sophie, Thomas, Julien, Lorthioir, Aurelien, Azizi, Michel, Chanson, Philippe, Le Bouc, Yves, Brailly-Tabard, Sylvie, Young, Jacques

“…Abstract Background Non-classic 21-hydroxylase deficiency is usually diagnosed in post-pubertal women because of androgen excess. Indication of systematic…”
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Epimutation of the telomeric imprinting center region on chromosome 11p15 in Silver-Russell syndrome by Thibaud, Nathalie, Netchine, Irène, Merrer, Martine Le, Steunou, Virginie, Bouc, Yves Le, Bertrand, Anne-Marie, Danton, Fabienne, Cabrol, Sylvie, Gicquel, Christine, Houang, Muriel, Burglen, Lydie, Rossignol, Sylvie, Barbu, Véronique

“…Silver-Russell syndrome (SRS, OMIM 180860) is a congenital disorder characterized by severe intrauterine and postnatal growth retardation, dysmorphic facial…”
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In Vitro Fertilization May Increase the Risk of Beckwith-Wiedemann Syndrome Related to the Abnormal Imprinting of the KCNQ1OT Gene by Gicquel, Christine, Gaston, Véronique, Mandelbaum, Jacqueline, Siffroi, Jean-Pierre, Flahault, Antoine, Le Bouc, Yves

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IGF-1 Induces GHRH Neuronal Axon Elongation during Early Postnatal Life in Mice by Decourtye, Lyvianne, Mire, Erik, Clemessy, Maud, Heurtier, Victor, Ledent, Tatiana, Robinson, Iain C, Mollard, Patrice, Epelbaum, Jacques, Meaney, Michael J, Garel, Sonia, Le Bouc, Yves, Kappeler, Laurent

“…Nutrition during the perinatal period programs body growth. Growth hormone (GH) secretion from the pituitary regulates body growth and is controlled by Growth…”
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Early Postnatal Nutrition Determines Somatotropic Function in Mice by Kappeler, Laurent, De Magalhaes Filho, Carlos, Leneuve, Patricia, Xu, Jie, Brunel, Nadège, Chatziantoniou, Christos, Le Bouc, Yves, Holzenberger, Martin

“…Increasing evidence suggests a developmental origin for a number of human diseases, notably after intrauterine or postnatal nutrient deprivation. Nutritional…”
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Cortisol and GH: odd and controversial ideas by Duclos, Martine, Guinot, Michel, Le Bouc, Yves

“…Activation of the hypothalamo-pituitary-adrenal (HPA) axis and of the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis represents a physiological…”
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Correction: IGF-1 Induces GHRH Neuronal Axon Elongation during Early Postnatal Life in Mice by Decourtye, Lyvianne, Mire, Erik, Clemessy, Maud, Heurtier, Victor, Ledent, Tatiana, Robinson, Iain C, Mollard, Patrice, Epelbaum, Jacques, Meaney, Michael J, Garel, Sonia, Le Bouc, Yves, Kappeler, Laurent

“…[This corrects the article DOI: 10.1371/journal.pone.0170083.]…”
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Clinical and molecular diagnosis, screening and management of Beckwith–Wiedemann syndrome: an international consensus statement by Brioude, Frédéric, Kalish, Jennifer M., Mussa, Alessandro, Foster, Alison C., Bliek, Jet, Ferrero, Giovanni Battista, Boonen, Susanne E., Cole, Trevor, Baker, Robert, Bertoletti, Monica, Cocchi, Guido, Coze, Carole, De Pellegrin, Maurizio, Hussain, Khalid, Ibrahim, Abdulla, Kilby, Mark D., Krajewska-Walasek, Malgorzata, Kratz, Christian P., Ladusans, Edmund J., Lapunzina, Pablo, Le Bouc, Yves, Maas, Saskia M., Macdonald, Fiona, Õunap, Katrin, Peruzzi, Licia, Rossignol, Sylvie, Russo, Silvia, Shipster, Caroleen, Skórka, Agata, Tatton-Brown, Katrina, Tenorio, Jair, Tortora, Chiara, Grønskov, Karen, Netchine, Irène, Hennekam, Raoul C., Prawitt, Dirk, Tümer, Zeynep, Eggermann, Thomas, Mackay, Deborah J. G., Riccio, Andrea, Maher, Eamonn R.

“…Beckwith–Wiedemann syndrome is an overgrowth disorder characterized by variable clinical phenotypes and a complex molecular aetiology. This Consensus Statement…”
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Genetic disruption of the oncogenic HMGA2–PLAG1–IGF2 pathway causes fetal growth restriction by Abi Habib, Walid, Brioude, Frédéric, Edouard, Thomas, Bennett, James T, Lienhardt-Roussie, Anne, Tixier, Frédérique, Salem, Jennifer, Yuen, Tony, Azzi, Salah, Le Bouc, Yves, Harbison, Madeleine D, Netchine, Irène

“…Purpose Fetal growth is a complex process involving maternal, placental and fetal factors. The etiology of fetal growth retardation remains unknown in many…”
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Cre-mediated germline mosaicism: a method allowing rapid generation of several alleles of a target gene by Holzenberger, M, Lenzner, C, Leneuve, P, Zaoui, R, Hamard, G, Vaulont, S, Bouc, Y L

“…Conditional gene targeting uses the insertion of expression cassettes for the selection of targeted embryonic stem cells. The presence of these cassettes in…”
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Delineating the interplay between oncogenic pathways and immunity in anaplastic Wilms tumors by Su, Xiaoping, Lu, Xiaofan, Bazai, Sehrish Khan, Dainese, Linda, Verschuur, Arnauld, Dumont, Benoit, Mouawad, Roger, Xu, Li, Cheng, Wenxuan, Yan, Fangrong, Irtan, Sabine, Lindner, Véronique, Paillard, Catherine, Le Bouc, Yves, Coulomb, Aurore, Malouf, Gabriel G.

“…Wilms tumors are highly curable in up to 90% of cases with a combination of surgery and radio-chemotherapy, but treatment-resistant types such as diffuse…”
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Stimulation of GHRH Neuron Axon Growth by Leptin and Impact of Nutrition during Suckling in Mice by Decourtye-Espiard, Lyvianne, Clemessy, Maud, Leneuve, Patricia, Mire, Erik, Ledent, Tatiana, Le Bouc, Yves, Kappeler, Laurent

“…Nutrition during the early postnatal period can program the growth trajectory and adult size. Nutritionally regulated hormones are strongly suspected to be…”
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Insulin-like Peptide 3 (INSL3) in Men With Congenital Hypogonadotropic Hypogonadism/Kallmann Syndrome and Effects of Different Modalities of Hormonal Treatment: A Single-Center Study of 281 Patients by Trabado, Séverine, Maione, Luigi, Bry-Gauillard, Hélène, Affres, Hélène, Salenave, Sylvie, Sarfati, Julie, Bouvattier, Claire, Delemer, Brigitte, Chanson, Philippe, Le Bouc, Yves, Brailly-Tabard, Sylvie, Young, Jacques

“…Context: Insulin-like factor 3 (INSL3) is a testicular hormone secreted during fetal life, the neonatal period, and after puberty. Objective: To measure INSL3…”
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A Liquid Chromatography/Tandem Mass Spectometry Profile of 16 Serum Steroids, Including 21-Deoxycortisol and 21-Deoxycorticosterone, for Management of Congenital Adrenal Hyperplasia by Fiet, Jean, Le Bouc, Yves, Guéchot, Jérôme, Hélin, Nicolas, Maubert, Marie-Anne, Farabos, Dominique, Lamazière, Antonin

“…Congenital adrenal hyperplasia (CAH) due to steroid 21-hydroxylase deficiency (CAH21) is most often diagnosed by newborn screening. The classic parameter…”
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Early energy deficit in Huntington disease: identification of a plasma biomarker traceable during disease progression by Mochel, Fanny, Charles, Perrine, Seguin, François, Barritault, Julie, Coussieu, Christiane, Perin, Laurence, Le Bouc, Yves, Gervais, Christiane, Carcelain, Guislaine, Vassault, Anne, Feingold, Josué, Rabier, Daniel, Durr, Alexandra

“…Huntington disease (HD) is a fatal neurodegenerative disorder, with no effective treatment. The pathogenic mechanisms underlying HD has not been elucidated,…”
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Deleting IGF-1 receptor from forebrain neurons confers neuroprotection during stroke and upregulates endocrine somatotropin by De Magalhaes Filho, C Daniel, Kappeler, Laurent, Dupont, Joëlle, Solinc, Julien, Villapol, Sonia, Denis, Cécile, Nosten-Bertrand, Marika, Billard, Jean-Marie, Blaise, Annick, Tronche, François, Giros, Bruno, Charriaut-Marlangue, Christiane, Aïd, Saba, Le Bouc, Yves, Holzenberger, Martin

“…Insulin-like growth factors control numerous processes, namely somatic growth, metabolism and stress resistance, connecting this pathway to aging and…”
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Insulin-Like Growth Factor-I and Insulin-Like Growth Factor Binding Protein-3 in Alzheimer's Disease by Duron, Emmanuelle, Funalot, Benoît, Brunel, Nadège, Coste, Joel, Quinquis, Laurent, Viollet, Cécile, Belmin, Joel, Jouanny, Pierre, Pasquier, Florence, Treluyer, Jean-Marc, Epelbaum, Jacques, le Bouc, Yves, Hanon, Olivier

“…Context: Few large studies have been conducted to assess the relationship between circulating IGF and late-life cognition. Objective: The aim of the study was…”
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IGF1 molecular anomalies demonstrate its critical role in fetal, postnatal growth and brain development by Netchine, Irène, MD, PhD, Azzi, Salah, PhD, Le Bouc, Yves, MD, PhD, Savage, Martin O., MD

“…The phenotype caused by human genetic insulin-like growth factor-I (IGF-I) defects is characterised by the association of intrauterine and postnatal growth…”
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