Search Results - "kumar Kalvala, Anil"

Adenosine monophosphate-activated protein kinase modulation by berberine attenuates mitochondrial deficits and redox imbalance in experimental diabetic neuropathy by Yerra, Veera Ganesh, Kalvala, Anil Kumar, Sherkhane, Bhoomika, Areti, Aparna, Kumar, Ashutosh

“…Adenosine monophosphate-activated protein kinase (AMPK) has been studied for its myriad metabolic and mitochondrial benefits in several chronic diseases…”
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Targeting AMPK in Diabetes and Diabetic Complications: Energy Homeostasis, Autophagy and Mitochondrial Health by Madhavi, Y V, Gaikwad, Nikhil, Yerra, Veera Ganesh, Kalvala, Anil Kumar, Nanduri, Srinivas, Kumar, Ashutosh

“…Adenosine 5'-monophosphate activated protein kinase (AMPK) is a key enzymatic protein involved in linking the energy sensing to the metabolic manipulation. It…”
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Role of Cannabidiol and Tetrahydrocannabivarin on Paclitaxel-induced neuropathic pain in rodents by Kumar Kalvala, Anil, Bagde, Arvind, Arthur, Peggy, Kumar Surapaneni, Sunil, Ramesh, Nimma, Nathani, Aakash, Singh, Mandip

“…•THCV, when combined with CBD, provides excellent neuroprotection against paclitaxel-induced peripheral neuropathy in mice.•THCV and CBD improve mitochondrial…”
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Rosmarinic Acid Mitigates Mitochondrial Dysfunction and Spinal Glial Activation in Oxaliplatin-induced Peripheral Neuropathy by Areti, Aparna, Komirishetty, Prashanth, Kalvala, Anil Kumar, Nellaiappan, Karthika, Kumar, Ashutosh

“…Chemotherapy-induced peripheral neuropathy (CIPN) is a dose-limiting complication which develops as a consequence of treatment with chemotherapeutic agents…”
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Ameliorative effect of fisetin on cisplatin-induced nephrotoxicity in rats via modulation of NF-κB activation and antioxidant defence by Sahu, Bidya Dhar, Kalvala, Anil Kumar, Koneru, Meghana, Mahesh Kumar, Jerald, Kuncha, Madhusudana, Rachamalla, Shyam Sunder, Sistla, Ramakrishna

“…Nephrotoxicity is a dose-dependent side effect of cisplatin limiting its clinical usage in the field of cancer chemotherapy. Fisetin is a bioactive flavonoid…”
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Probucol attenuates NF-κB/NLRP3 signalling and augments Nrf-2 mediated antioxidant defence in nerve injury induced neuropathic pain by Derangula, Kalyani, Javalgekar, Mohit, kumar Arruri, Vijay, Gundu, Chayanika, kumar Kalvala, Anil, kumar, Ashutosh

“…•CCI of sciatic nerve resulted in long-lasting hyperalgesia and allodynia in rats.•Unregulated activation of NF-κB/Nlrp3 inflammasome contributed to CCI…”
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An Overview on ATP Dependent and Independent Proteases Including an Anterograde to Retrograde Control on Mitochondrial Function; Focus on Diabetes and Diabetic Complications by Kalvala, Anil Kumar, Khan, Islauddin, Gundu, Chayanika, Kumar, Ashutosh

“…Mitochondria are the central power stations of the cell involved with a myriad of cell signalling pathways that contribute for whole health status of the cell…”
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Cannabidiol-Loaded Extracellular Vesicles from Human Umbilical Cord Mesenchymal Stem Cells Alleviate Paclitaxel-Induced Peripheral Neuropathy by Kalvala, Anil Kumar, Bagde, Arvind, Arthur, Peggy, Kulkarni, Tanmay, Bhattacharya, Santanu, Surapaneni, Sunil, Patel, Nil Kumar, Nimma, Ramesh, Gebeyehu, Aragaw, Kommineni, Nagavendra, Meckes, Jr, David G, Sun, Li, Banjara, Bipika, Mosley-Kellum, Keb, Dinh, Thanh Cong, Singh, Mandip

“…In cancer patients, chronic paclitaxel (PTX) treatment causes excruciating pain, limiting its use in cancer chemotherapy. The neuroprotective potential of…”
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Combined Transcriptomic and Proteomic Profiling to Unravel Osimertinib, CARP-1 Functional Mimetic (CFM 4.17) Formulation and Telmisartan Combo Treatment in NSCLC Tumor Xenografts by Nimma, Ramesh, Kalvala, Anil Kumar, Patel, Nilkumar, Surapaneni, Sunil Kumar, Sun, Li, Singh, Rakesh, Nottingham, Ebony, Bagde, Arvind, Kommineni, Nagavendra, Arthur, Peggy, Nathani, Aakash, Meckes, David G, Singh, Mandip

“…The epidermal growth factor receptor (EGFR) is highly expressed in many non-small cell lung cancers (NSCLC), necessitating the use of EGFR-tyrosine kinase…”
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Correction: Kalvala et al. Cannabidiol-Loaded Extracellular Vesicles from Human Umbilical Cord Mesenchymal Stem Cells Alleviate Paclitaxel-Induced Peripheral Neuropathy. Pharmaceutics 2023, 15, 554 by Kalvala, Anil Kumar, Bagde, Arvind, Arthur, Peggy, Kulkarni, Tanmay, Bhattacharya, Santanu, Surapaneni, Sunil, Patel, Nil Kumar, Nimma, Ramesh, Gebeyehu, Aragaw, Kommineni, Nagavendra, Li, Yan, Meckes, David G., Sun, Li, Banjara, Bipika, Mosley-Kellum, Keb, Dinh, Thanh Cong, Singh, Mandip

“…“Yan Li” was not included as an author in the original publication [...]…”
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Isoliquiritigenin reduces oxidative damage and alleviates mitochondrial impairment by SIRT1 activation in experimental diabetic neuropathy by Yerra, Veera Ganesh, Kalvala, Anil Kumar, Kumar, Ashutosh

“…Sirtuin (SIRT1) inactivation underlies the pathogenesis of insulin resistance and hyperglycaemia-associated vascular complications, but its role in diabetic…”
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LONP1 induction by SRT1720 attenuates mitochondrial dysfunction against high glucose induced neurotoxicity in PC12 cells by Kalvala, Anil Kumar, Yerra, Veera Ganesh, Kumar, Ashutosh

“…Neuropathies caused by mitochondrial dysfunction are the most common and serious impediment of high glucose (HG)-induced toxicity. We have previously reported…”
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SIRT1 Activation by Polydatin Alleviates Oxidative Damage and Elevates Mitochondrial Biogenesis in Experimental Diabetic Neuropathy by Bheereddy, Preethi, Yerra, Veera Ganesh, Kalvala, Anil Kumar, Sherkhane, Bhoomika, Kumar, Ashutosh

“…Mitochondrial dysfunction has been implicated as a one of the major factors linked to the development of painful diabetic neuropathy (DN). Several studies have…”
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Carvacrol abates NLRP3 inflammasome activation by augmenting Keap1/Nrf-2/p62 directed autophagy and mitochondrial quality control in neuropathic pain by Arruri, Vijay Kumar, Gundu, Chayanika, Kalvala, Anil Kumar, Sherkhane, Bhoomika, Khatri, Dharmendra Kumar, Singh, Shashi Bala

“…Objectives: We aimed to evaluate the effect of carvacrol (CRC), a phenolic monoterpene with high nutritional value on NLRP3 activation against chronic…”
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Morin exerts neuroprotection via attenuation of ROS induced oxidative damage and neuroinflammation in experimental diabetic neuropathy by Bachewal, Pragna, Gundu, Chayanika, Yerra, Veera Ganesh, Kalvala, Anil Kumar, Areti, Aparna, Kumar, Ashutosh

“…Morin, a bioflavonoid with diverse pharmacological effects against various diseases; in most cases morin protective effects were attributed to its detoxifying…”
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Applications of Cannabinoids in Neuropathic Pain: An Updated Review by Arthur, Peggy, Kalvala, Anil Kumar, Surapaneni, Sunil Kumar, Singh, Mandip Sachdeva

“…Neuropathic pain is experienced due to injury to the nerves, underlying disease conditions or toxicity induced by chemotherapeutics. Multiple factors can…”
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Bardoxolone Methyl Ameliorates Hyperglycemia Induced Mitochondrial Dysfunction by Activating the keap1-Nrf2-ARE Pathway in Experimental Diabetic Neuropathy by Kalvala, Anil Kumar, Kumar, Rahul, Sherkhane, Bhoomika, Gundu, Chayanika, Arruri, Vijay Kumar, Kumar, Ashutosh

“…Bardoxolone methyl (Bard), a nuclear factor erythroid 2-related factor 2 (Nrf2) activator regulates multiple oxidative and inflammatory diseases. However, the…”
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The role of Cannabidiol and tetrahydrocannabivarin to overcome doxorubicin resistance in MDA-MB-231 xenografts in athymic nude mice by Kalvala, Anil Kumar, Nimma, Ramesh, Bagde, Arvind, Surapaneni, Sunil Kumar, Patel, Nilkumar, Arthur, Peggy, Sun, Li, Singh, Rakesh, Kommineni, Nagavendra, Nathani, Aakash, Li, Yan, Singh, Mandip

“…The significant resistance to currently available chemotherapeutics makes treatment for TNBC a key clinical concern. Herein, we studied the anti-cancer…”
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Renoprotective potential of myo‐inositol on diabetic kidney disease: Focus on the role of the PINK1/Parkin pathway and mitophagy receptors by Sherkhane, Bhoomika, Kalvala, Anil Kumar, Arruri, Vijay Kumar, Khatri, Dharmendra kumar, Singh, Shashi Bala

“…Recent studies have emphasized the role of mitochondria in renal function as well as in renal injury. Poor mitochondrial quality control mechanisms including…”
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Telmisartan Facilitates the Anticancer Effects of CARP-1 Functional Mimetic and Sorafenib in Rociletinib Resistant Non-small Cell Lung Cancer by Surapaneni, Sunil Kumar, Nottingham, Ebony, Mondal, Arindam, Patel, Nilkumar, Arthur, Peggy, Gebeyehu, Aragaw, Kalvala, Anil Kumar, Rishi, Arun K, Singh, Mandip

“…Tyrosine kinase inhibitors (TKIs) are used for the treatment of both wild type and mutant non-small cell lung cancer (NSCLC); however, acquired resistance is a…”
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