Search Results - "klaff, Justin"

Long-Term Efficacy and Safety of Upadacitinib in Patients with Rheumatoid Arthritis: Final Results from the BALANCE-EXTEND Open-Label Extension Study by Kivitz, Alan, Wells, Alvin F., Vargas, Juan I., Baraf, Herbert S. B., Rischmueller, Maureen, Klaff, Justin, Khan, Nasser, Li, Yihan, Carter, Kyle, Friedman, Alan, Durez, Patrick

“…Introduction Upadacitinib (UPA) is an oral, selective Janus kinase inhibitor that has demonstrated favorable efficacy with an acceptable safety profile across…”
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S1080 Corticosteroid-Free Remission Through 3 Years of Upadacitinib Therapy in Patients With Moderately to Severely Active Ulcerative Colitis: Data From the Phase 3 Long-Term Extension Study U-ACTIVATE by Dubinsky, Marla, Atreya, Raja, Nakase, Hiroshi, Kujawski, Michelle, Crooks, James, Cheng, Erica, Klaff, Justin, Panaccione, Remo

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Tu1732 SAFETY OF UPADACITINIB IN ULCERATIVE COLITIS: LONG-TERM DATA FROM THE PHASE 3 OPEN-LABEL EXTENSION STUDY (U-ACTIVATE) by Panaccione, Remo, Lichtenstein, Gary R., Nakase, Hiroshi, Armuzzi, Alessandro, Kucharzik, Torsten, Levy, Gweneth, Palac, Hannah, Kujawski, Michelle, klaff, Justin, Cheon, Jae Hee

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Tu1737 THE EFFECTS OF UPADACITINIB ON ULCERATIVE COLITIS SYMPTOM RESOLUTION AND FATIGUE NORMALIZATION IN PATIENTS WITH MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS: PHASE 3 UACHIEVE AND U-ACCOMPLISH RESULTS by D'Haens, Geert, Tran, Jacinda N., Danese, Silvio, Rubin, David T., Aoyama, Nobuo, Lügering, Andreas, klaff, Justin, Xuan, Si, Ilo, Dapo, Gonzalez, Yuri Sanchez, Panés, Julián

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P128 Long-term safety and efficacy of upadacitinib in patients with rheumatoid arthritis: final results from the BALANCE-EXTEND open-label extension study by Kivitz, Alan, Wells, Alvin F, Vargas, Juan I, Baraf, Herbert S B, Rischmueller, Maureen, Klaff, Justin, Khan, Nasser, Li, Yihan, Carter, Kyle, Friedman, Alan, Durez, Patrick

“…Abstract Background/Aims Upadacitinib (UPA) was previously evaluated in two Phase 2, randomized, controlled trials (RCTs) in patients (pts) with rheumatoid…”
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966: EFFICACY AND SAFETY OF EXTENDED INDUCTION TREATMENT WITH UPADACITINIB 45 MG ONCE DAILY FOLLOWED BY MAINTENANCE UPADACITINIB 15 OR 30 MG ONCE DAILY IN PATIENTS WITH MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS by Vermeire, Séverine, Danese, Silvio, Zhou, Wen, klaff, Justin, Ilo, Dapo, Yao, Xuan, Levy, Gweneth, Higgins, Peter D., Loftus, Edward V., Panaccione, Remo

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S722 Efficacy and Safety of Upadacitinib in Patients With Moderate to Severe Active Ulcerative Colitis Receiving 16 Weeks Extended Induction Treatment Followed by 52 Weeks Maintenance Treatment in U-ACHIEVE/U-ACCOMPLISH Trials by Panaccione, Remo, Danese, Silvio, Zhou, Wen, Klaff, Justin, Ilo, Dapo, Yao, Xuan, Levy, Gweneth, Higgins, Peter D., Loftus, Edward V., Vermeire, Séverine

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Tu1477: UPADACITINIB PROMOTES HISTOLOGIC AND ENDOSCOPIC MUCOSAL HEALING: RESULTS FROM THE UPADACITINIB ULCERATIVE COLITIS PHASE 3 PROGRAM by Peyrin-Biroulet, Laurent, Siegel, Corey A., Tanida, Satoshi, Bossuyt, Peter, Torres, Esther A., Dubinsky, Marla, Baert, Filip J., Zhou, Wen, Klaff, Justin, Berg, Sofie, Laroux, Stephen, Gonzalez, Yuri Sanchez, Yao, Xuan, Zhou, Qing, Reinisch, Walter

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S1193 Safety of Upadacitinib in IBD: Pooled Analysis of Phase 3 Maintenance Studies, U-ACHIEVE and U-ENDURE, In Patients With Moderately to Severely Active Ulcerative Colitis or Crohn’s Disease by Panaccione, Remo, Panés, Julian, Peyrin-Biroulet, Laurent, Colombel, Jean-Frederic, Lindsay, James, Baert, Filip, Atreya, Raja, Lacerda, Ana P., Park, Caroline, Anyanwu, Samuel I., Klaff, Justin, Liu, Jianzhong, Levy, Gweneth, Duncan, Benjamin, Vladea, Ramona, Rubin, David T.

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Efficacy and safety of upadacitinib for 16‐week extended induction and 52‐week maintenance therapy in patients with moderately to severely active ulcerative colitis by Panaccione, Remo, Danese, Silvio, Zhou, Wen, Klaff, Justin, Ilo, Dapo, Yao, Xuan, Levy, Gweneth, Higgins, Peter D. R., Loftus, Edward V., Chen, Su, Gonzalez, Yuri Sanchez, Leonard, Carolyn, Hébuterne, Xavier, Lindsay, James O., Cao, Qian, Nakase, Hiroshi, Colombel, Jean‐Frédéric, Vermeire, Séverine

“…Summary Background Upadacitinib is an oral, selective Janus kinase inhibitor. Aim To assess the efficacy and safety of upadacitinib in patients with…”
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A mobile app for measuring the surface area of a burn in three dimensions: comparison to the Lund and Browder assessment by Goldberg, Harry, Klaff, Justin, Spjut, Aaron, Milner, Stephen

“…The aim of this study was to compare the ease and accuracy of measuring the surface area of a severe burn through the use of a mobile software application…”
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Evaluation of response to 13-valent conjugated pneumococcal vaccination in patients with rheumatoid arthritis receiving upadacitinib: results from a phase 2 open-label extension study by Winthrop, Kevin, Vargas, Juan Ignacio, Drescher, Edit, Garcia, Conrado, Friedman, Alan, Hendrickson, Barbara, Li, Yihan, Klaff, Justin, Kivitz, Alan

“…To assess the immunogenicity of pneumococcal 13-valent conjugate vaccination (PCV-13) in patients with rheumatoid arthritis receiving upadacitinib and…”
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Imaging brain phospholipase A2 activation in awake rats in response to the 5-HT2A/2C agonist (+/-)2,5-dimethoxy-4-iodophenyl-2-aminopropane (DOI) by Qu, Ying, Chang, Lisa, Klaff, Justin, Balbo, Andrea, Rapoport, Stanley I

“…Incorporation coefficients k(*) of intravenously injected [(3)H]arachidonic acid from blood into brain reflect the release from phospholipids of arachidonic…”
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Chronic fluoxetine upregulates arachidonic acid incorporation into the brain of unanesthetized rats by Qu, Ying, Chang, Lisa, Klaff, Justin, Seemann, Ruth, Greenstein, Deanna, Rapoport, Stanley I.

“…Serotonergic 5-HT2A/2C receptors can be coupled to phospholipase A2 (PLA2) activation to release the second messenger, arachidonic acid (AA), from membrane…”
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Chemical burn to the eyes by Klaff, Justin, Milner, Stephen M, Farris, Stuart, Price, Leigh Ann

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Imaging brain phospholipase A2-mediated signal transduction in response to acute fluoxetine administration in unanesthetized rats by YING QU, CHANG, Lisa, KLAFF, Justin, SEEMANN, Ruth, RAPOPORT, Stanley I

“…Fluoxetine, a selective serotonin (5-hydroxytryptamine, 5-HT) reuptake inhibitor, is used widely to treat depression and related disorders. By inhibiting…”
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A shot in the face by Price, Leigh Ann, Klaff, Justin, Brown, Emile, Milner, Stephen M

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Topics in burn critical care-chest pain by Shah, Neeraj M, Klaff, Justin, Milner, Stephen M, Price, Leigh A, Gerold, Kevin B

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Imaging of brain serotonergic neurotransmission involving phospholipase A2 activation and arachidonic acid release in unanesthetized rats by Qu, Ying, Chang, Lisa, Klaff, Justin, Seeman, Ruth, Balbo, Andrea, Rapoport, Stanley I

“…In vitro studies have shown that 5-HT2 receptors can be coupled via G-proteins to phospholipase A2 (PLA2) activation, releasing arachidonic acid from…”
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Imaging of brain serotonergic neurotransmission involving phospholipase A 2 activation and arachidonic acid release in unanesthetized rats by Qu, Ying, Chang, Lisa, Klaff, Justin, Seeman, Ruth, Balbo, Andrea, Rapoport, Stanley I.

“…In vitro studies have shown that 5-HT 2 receptors can be coupled via G-proteins to phospholipase A 2 (PLA 2) activation, releasing arachidonic acid from…”
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