Search Results - "kitano, shiro"
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Engineered whole cut meat-like tissue by the assembly of cell fibers using tendon-gel integrated bioprinting
Published in Nature communications (24-08-2021)“…With the current interest in cultured meat, mammalian cell-based meat has mostly been unstructured. There is thus still a high demand for artificial steak-like…”
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Biomacromolecule‐Fueled Transient Volume Phase Transition of a Hydrogel
Published in Angewandte Chemie International Edition (15-08-2022)“…A metabolic cycle‐inspired hydrogel which exhibits the biomacromolecule‐fueled transient volume phase transition is reported. This hydrogel has the affinity…”
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3
3D collagen microfibers stimulate the functionality of preadipocytes and maintain the phenotype of mature adipocytes for long term cultures
Published in Acta biomaterialia (15-01-2019)“…[Display omitted] Although adipose tissue is one of the most abundant tissues of the human body, its reconstruction remains a competitive challenge. The…”
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Cellular memory function from 3D to 2D: Three-dimensional high density collagen microfiber cultures induce their resistance to reactive oxygen species
Published in Materials today bio (01-06-2024)“…Cell properties generally change when the culture condition is changed. However, mesenchymal stem cells cultured on a hard material surface maintain their…”
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Utility of KRAS mutation detection using circulating cell‐free DNA from patients with colorectal cancer
Published in Cancer science (01-07-2016)“…In this study, we evaluated the clinical utility of detecting KRAS mutations in circulating cell‐free (ccf)DNA of metastatic colorectal cancer patients. We…”
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Constructing vascularized hepatic tissue by cell-assembled viscous tissue sedimentation method and its application for vascular toxicity assessment
Published in Acta biomaterialia (01-03-2022)“…In vitro Construction of the liver sinusoidal structure using artificial tissue is an important but worthwhile challenge, particularly for assessing the risk…”
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Injectable Prevascularized Mature Adipose Tissues (iPAT) to Achieve Long‐Term Survival in Soft Tissue Regeneration
Published in Advanced healthcare materials (01-12-2022)“…Soft tissue regeneration remains a challenge in reconstructive surgery. So far, both autologous fat implantations and artificial implants methods used in…”
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High-throughput drug screening models of mature adipose tissues which replicate the physiology of patients’ Body Mass Index (BMI)
Published in Bioactive materials (01-01-2022)“…Obesity is a complex and incompletely understood disease, but current drug screening strategies mostly rely on immature in vitro adipose models which cannot…”
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Bioprinted Vascularized Mature Adipose Tissue with Collagen Microfibers for Soft Tissue Regeneration
Published in Cyborg and bionic systems (01-01-2021)“…The development of soft tissue regeneration has recently gained importance due to safety concerns about artificial breast implants. Current autologous fat…”
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Enrichment technique to allow early detection and monitor emergence of KRAS mutation in response to treatment
Published in Scientific reports (05-08-2019)“…Sensitivity of cell-free circulating tumour DNA (ctDNA) assays is often hampered by the limited quantity of intact mutant nucleotide fragments. To overcome the…”
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Detection of DNA mutations by fluorescence resonance energy transfer-based preferential homoduplex formation assay
Published in Analytical biochemistry (15-01-2011)“…Molecularly targeted agents for cancer therapy are recognized as being effective and are gaining in popularity. However, the efficacy of the agents depends on…”
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A novel fully automated molecular diagnostic system (AMDS) for colorectal cancer mutation detection
Published in PloS one (09-05-2013)“…KRAS, BRAF and PIK3CA mutations are frequently observed in colorectal cancer (CRC). In particular, KRAS mutations are strong predictors for clinical outcomes…”
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Collagen Microfibers Induce Blood Capillary Orientation and Open Vascular Lumen
Published in Advanced biosystems (01-05-2020)“…Achieving vascularization of engineered tissues or structures is a major challenge in the field of tissue engineering. Hitherto, studies on vascularization…”
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Frontispiece: Biomacromolecule‐Fueled Transient Volume Phase Transition of a Hydrogel
Published in Angewandte Chemie International Edition (15-08-2022)“…Hydrogels. In their Communication (e202205125), Michiya Matsusaki et al. describe a metabolic‐cycle‐inspired hydrogel that exhibits a biomacromolecule‐fueled…”
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Abstract 3877: A unique layered 3D stromal tissue model for in vitro evaluation of immunologic agents and immune cell infiltration into microenviroment
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Background The modulation of the immune system is a proven key target for cancer therapy, however, the complex interplay between immune cells and cancer cells…”
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Capillary Alignment: Collagen Microfibers Induce Blood Capillary Orientation and Open Vascular Lumen (Adv. Biosys. 5/2020)
Published in Advanced biosystems (01-05-2020)“…In article number 2000038, Michiya Matsusaki and co‐workers demonstrate a method based on high water‐dispersible collagen microfibers (CMF‐20) to fabricate 3D…”
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Promoting biological similarity by collagen microfibers in 3D colorectal cancer-stromal tissue: Replicating mechanical properties and cancer stem cell markers
Published in Acta biomaterialia (01-09-2024)“…The extracellular matrix (ECM) of cancer tissues is rich in dense collagen, contributing to the stiffening of these tissues. Increased stiffness has been…”
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18
Biomacromolecule‐Fueled Transient Volume Phase Transition of a Hydrogel
Published in Angewandte Chemie (15-08-2022)“…A metabolic cycle‐inspired hydrogel which exhibits the biomacromolecule‐fueled transient volume phase transition is reported. This hydrogel has the affinity…”
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Frontispiz: Biomacromolecule‐Fueled Transient Volume Phase Transition of a Hydrogel
Published in Angewandte Chemie (15-08-2022)“…Hydrogele. Michiya Matsusaki et al. präsentieren in ihrer Zuschrift (e202205125) ein Hydrogel, das einen durch Biomakromoleküle angetriebenen Phasenübergang…”
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Abstract 1151: A unique layered 3D stromal tissue model for in vitro evaluation of immunologic agents and immune cell infiltration into cancer microenvironment
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Background; The modulation of the immune system is a proven key target for cancer therapy, however, the complex interplay between immune cells and cancer cells…”
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