Search Results - "khayat, André Salim"
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EndoGeneAnalyzer: A tool for selection and validation of reference genes
Published in PloS one (03-04-2024)“…The selection of proper reference genes is critical for accurate gene expression analysis in all fields of biological and medical research, mainly because…”
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A small interfering RNA (siRNA) database for SARS-CoV-2
Published in Scientific reports (23-04-2021)“…Coronavirus disease 2019 (COVID-19) rapidly transformed into a global pandemic, for which a demand for developing antivirals capable of targeting the…”
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ACE2 polymorphisms as potential players in COVID-19 outcome
Published in PloS one (28-12-2020)“…The clinical condition COVID-19, caused by SARS-CoV-2, was declared a pandemic by the WHO in March 2020. Currently, there are more than 5 million cases…”
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Extraction, Characterization, and Evaluation of the Cytotoxic Activity of Piperine in Its Isolated form and in Combination with Chemotherapeutics against Gastric Cancer
Published in Molecules (Basel, Switzerland) (01-07-2023)“…Gastric cancer is one of the most frequent types of neoplasms worldwide, usually presenting as aggressive and difficult-to-manage tumors. The search for new…”
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Antiproliferative, genotoxic activities and quantification of extracts and cucurbitacin B obtained from Luffa operculata (L.) Cogn
Published in Arabian journal of chemistry (01-02-2022)“…The medicinal plant Luffa operculata (L.) Cogn. has therapeutic properties in the treatment of sinusitis, rhinitis and abortifacient conditions…”
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Risk Polymorphisms of FNDC5 , BDNF , and NTRK2 and Poor Education Interact and Aggravate Age-Related Cognitive Decline
Published in International journal of molecular sciences (07-12-2023)“…Cognitive abilities tend to decline with aging, with variation between individuals, and many studies seek to identify genetic biomarkers that more accurately…”
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Upregulated miRNAs on the TP53 and RB1 Binding Seedless Regions in High-Risk HPV-Associated Penile Cancer
Published in Frontiers in genetics (24-06-2022)“…Cancer development by the human papillomavirus (HPV) infection can occur through the canonical HPV/p53/RB1 pathway mediated by the E2/E6/E7 viral oncoproteins…”
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APC gene is modulated by hsa-miR-135b-5p in both diffuse and intestinal gastric cancer subtypes
Published in BMC cancer (30-10-2018)“…Several genetic and epigenetic alterations are related to the development and progression of Gastric Cancer (GC), one of those being the deregulated microRNA…”
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Suicide journey of H. pylori through gastric carcinogenesis: the role of non-H. pylori microbiome and potential consequences for clinical practice
Published in European journal of clinical microbiology & infectious diseases (01-09-2019)“…Despite being one of the most studied cancer-related infections, the relationship between Helicobacter pylori infection and gastric adenocarcinoma (GC)…”
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Solid Tumors and Kinase Inhibition: Management and Therapy Efficacy Evolution
Published in International journal of molecular sciences (30-03-2022)“…The increasing numbers of cancer cases worldwide and the exceedingly high mortality rates of some tumor subtypes raise the question about if the current…”
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Circadian Rhythm Dysregulation and Leukemia Development: The Role of Clock Genes as Promising Biomarkers
Published in International journal of molecular sciences (01-08-2022)“…The circadian clock (CC) is a daily system that regulates the oscillations of physiological processes and can respond to the external environment in order to…”
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12
Acai Oil-Based Organogel Containing Hyaluronic Acid for Topical Cosmetic: In Vitro and Ex Vivo Assessment
Published in Pharmaceutics (11-09-2024)“…Organogels are semi-solid pharmaceutical forms whose dispersing phase is an organic liquid, for example, an oil, such as acai oil, immobilized by a…”
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13
What is the role of circRNAs in the pathogenesis of cervical cancer? A systematic literature review
Published in Frontiers in genetics (27-05-2024)“…Cervical Cancer (CC) is one of the most prevalent neoplasms among women, considered the leading cause of gynecological death worldwide, and the fourth most…”
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Evaluation of Antimicrobial Activity and Cytotoxicity Effects of Extracts of Piper nigrum L. and Piperine
Published in Separations (01-01-2023)“…P. nigrum L. extracts and the piperine alkaloid have important antimicrobial, anti-inflammatory, and antioxidant properties. Therefore, in this study, we…”
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Leukemic Stem Cell: A Mini-Review on Clinical Perspectives
Published in Frontiers in oncology (24-06-2022)“…Hematopoietic stem cells (HSCs) are known for their ability to proliferate and self-renew, thus being responsible for sustaining the hematopoietic system and…”
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The Role of WRAP53 in Cell Homeostasis and Carcinogenesis Onset
Published in Current issues in molecular biology (01-11-2022)“…The WD repeat containing antisense to TP53 (WRAP53) gene codifies an antisense transcript for tumor protein p53 (TP53), stabilization (WRAP53α), and a…”
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Prognostic and predictive significance of MYC and KRAS alterations in breast cancer from women treated with neoadjuvant chemotherapy
Published in PloS one (26-03-2013)“…Breast cancer is a complex disease, with heterogeneous clinical evolution. Several analyses have been performed to identify the risk factors for breast cancer…”
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Identification and Characterization of Polymorphisms in piRNA Regions
Published in Current issues in molecular biology (15-02-2022)“…piRNAs are a class of noncoding RNAs that perform functions in epigenetic regulation and silencing of transposable elements, a mechanism conserved among most…”
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MYC, FBXW7 and TP53 copy number variation and expression in gastric cancer
Published in BMC gastroenterology (23-09-2013)“…MYC deregulation is a common event in gastric carcinogenesis, usually as a consequence of gene amplification, chromosomal translocations, or posttranslational…”
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Association between Immunophenotypic Parameters and Molecular Alterations in Acute Myeloid Leukemia
Published in Biomedicines (01-04-2023)“…Acute myeloid leukemia (AML) is a hematologic malignancy that occurs due to alterations such as genetic mutations, chromosomal translocations, or changes in…”
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