Search Results - "katie Wilson"

DNA-protein π-interactions in nature: abundance, structure, composition and strength of contacts between aromatic amino acids and DNA nucleobases or deoxyribose sugar by Wilson, Katie A, Kellie, Jennifer L, Wetmore, Stacey D

“…Four hundred twenty-eight high-resolution DNA-protein complexes were chosen for a bioinformatics study. Although 164 crystal structures (38% of those searched)…”
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Stereoselective Single Step Cyclization to Give Belt-Functionalized Pillar[6]arenes by Coady, Zeke, Smith, Jordan N., Wilson, Katie A., White, Nicholas G.

“…Two macrocycles were synthesized through cyclization reactions of secondary benzylic alcohols, giving pillar[6]­arenes with a methyl substituent at each belt…”
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Long-term tracking of cells using inorganic nanoparticles as contrast agents: are we there yet? by Taylor, Arthur, Wilson, Katie M, Murray, Patricia, Fernig, David G, Lévy, Raphaël

“…The use of inorganic nanoparticles as probes to label and track cells in vivo is already a reality. While superparamagnetic nanoparticles have been the subject…”
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Evaluating the impact of open access policies on research institutions by Huang, Chun-Kai Karl, Neylon, Cameron, Hosking, Richard, Montgomery, Lucy, Wilson, Katie S, Ozaygen, Alkim, Brookes-Kenworthy, Chloe

“…The proportion of research outputs published in open access journals or made available on other freely-accessible platforms has increased over the past two…”
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A probabilistic model for analyzing summary birth history data by Wilson, Katie, Wakefield, Jon

“…There is an increasing demand for high-quality subnational estimates of under-5 mortality. In low- and middle-income countries, where the burden of under-5…”
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Polyunsaturated lipids promote membrane phase separation and antimicrobial sensitivity by MacDermott-Opeskin, Hugo, Wilson, Katie A., Eijkelkamp, Bart, O'Mara, Megan L.

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Anatomy of noncovalent interactions between the nucleobases or ribose and π-containing amino acids in RNA–protein complexes by Wilson, Katie A, Kung, Ryan W, D’souza, Simmone, Wetmore, Stacey D

“…Abstract A set of >300 nonredundant high-resolution RNA–protein complexes were rigorously searched for π-contacts between an amino acid side chain (W, H, F, Y,…”
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Multiscale computational investigations of the translesion synthesis bypass of tobacco-derived DNA adducts: critical insights that complement experimental biochemical studies by Wilson, Katie A, Jeong, Ye Eun Rebecca, Wetmore, Stacey D

“…Among the numerous agents that damage DNA, tobacco products remain one of the most lethal and result in the most diverse set of DNA lesions. This perspective…”
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Topology of RNA-protein nucleobase-amino acid π-π interactions and comparison to analogous DNA-protein π-π contacts by Wilson, Katie A, Holland, Devany J, Wetmore, Stacey D

“…The present work analyzed 120 high-resolution X-ray crystal structures and identified 335 RNA-protein π-interactions (154 nonredundant) between a nucleobase…”
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Feedback in augmented and virtual reality piano tutoring systems: a mini review by Wilson, Katie, Pfeiffer, Phillip E.

“…Researchers in music education are exploring the use of virtual reality (VR) and augmented reality (AR) to support piano instruction. Beginner piano students…”
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Amphetamine-like Deferiprone and Clioquinol Derivatives as Iron Chelating Agents by El Safadi, Mahmoud, Wilson, Katie A, Strudwicke, Indigo J, O'Mara, Megan L, Bhadbhade, Mohan, Rawling, Tristan, McDonagh, Andrew M

“…The accumulation of iron in dopaminergic neurons can cause oxidative stress and dopaminergic neuron degeneration. Iron chelation therapy may reduce…”
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High resolution crystal structure of a KRAS promoter G-quadruplex reveals a dimer with extensive poly-A π-stacking interactions for small-molecule recognition by Ou, Arnold, Schmidberger, Jason W, Wilson, Katie A, Evans, Cameron W, Hargreaves, Jessica A, Grigg, Melanie, O'Mara, Megan L, Iyer, K Swaminathan, Bond, Charles S, Smith, Nicole M

“…Aberrant KRAS signaling is a driver of many cancers and yet remains an elusive target for drug therapy. The nuclease hypersensitive element of the KRAS…”
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Understanding the Link between Lipid Diversity and the Biophysical Properties of the Neuronal Plasma Membrane by Wilson, Katie A, MacDermott-Opeskin, Hugo I, Riley, Eden, Lin, Yiechang, O’Mara, Megan L

“…Cell membranes contain incredible diversity in the chemical structures of their individual lipid species and the ratios in which these lipids are combined to…”
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Uncovering a unique approach for damaged DNA replication: A computational investigation of a mutagenic tobacco-derived thymine lesion by Wilson, Katie A, Holland, Carl D, Wetmore, Stacey D

“…Abstract 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone is a potent nicotine carcinogen that leads to many DNA lesions, the most persistent being the…”
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The role of ATP-binding Cassette subfamily B member 6 in the inner ear by Baril, Stefanie A., Wilson, Katie A., Shaik, Md Munan, Fukuda, Yu, Umans, Robyn A., Barbieri, Alessandro, Lynch, John, Gose, Tomoka, Myasnikov, Alexander, Oldham, Michael L., Wang, Yao, Zhu, Jingwen, Fang, Jie, Zuo, Jian, Kalathur, Ravi C., Ford, Robert C., Coffin, Allison, Taylor, Michael R., O’Mara, Megan L., Schuetz, John D.

“…ABCB6 has been implicated in dyschromatosis universalis hereditaria, a condition characterized by hyperpigmented and hypopigmented skin macules. Dyschromatosis…”
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Computational Insight into the Differential Mutagenic Patterns of O‑Methylthymine Lesions by Bhutani, Priya, Nikkel, Dylan J, Wilson, Katie A, Wetmore, Stacey D

“…Differential mutagenic patterns were recently reported for O-methylated thymine lesions, which indicate that O4-methylthymine (O4-Me-T) frequently leads to G…”
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Structural Rationalization for the Nonmutagenic and Mutagenic Bypass of the Tobacco-Derived O4-4-(3-Pyridyl)-4-oxobut-1-yl-thymine Lesion by Human Polymerase η: A Multiscale Computational Study by Bhutani, Priya, Murray, Makay T, Sommer, Craig W, Wilson, Katie A, Wetmore, Stacey D

“…Tobacco-derived pyridyloxobutyl (POB) DNA adducts are unique due to the large size and flexibility of the alkyl chain connecting the pyridyl ring to the…”
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Conformational Flexibility of the Benzyl-Guanine Adduct in a Bypass Polymerase Active Site Permits Replication: Insights from Molecular Dynamics Simulations by Wilson, Katie A, Wetmore, Stacey D

“…Although translesion synthesis (TLS) polymerases play key roles in replicating DNA that contains nucleobase addition products (adducts), there are many…”
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An ONIOM and MD Investigation of Possible Monofunctional Activity of Human 8‑Oxoguanine–DNA Glycosylase (hOgg1) by Kellie, Jennifer L, Wilson, Katie A, Wetmore, Stacey D

“…Since the formation of 8-oxoguanine (OG) is one of the most common DNA-damaging events, cells have evolved efficient repair processes to avoid the mutagenic…”
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The allosteric inhibition of glycine transporter 2 by bioactive lipid analgesics is controlled by penetration into a deep lipid cavity by Wilson, Katie A., Mostyn, Shannon N., Frangos, Zachary J., Shimmon, Susan, Rawling, Tristan, Vandenberg, Robert J., O’Mara, Megan L.

“…The role of lipids in modulating membrane protein function is an emerging and rapidly growing area of research. The rational design of lipids that target…”
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