Search Results - "johnston, S L"

Th2 cytokines impair innate immune responses to rhinovirus in respiratory epithelial cells by Contoli, M., Ito, K., Padovani, A., Poletti, D., Marku, B., Edwards, M. R., Stanciu, L. A., Gnesini, G., Pastore, A., Spanevello, A., Morelli, P., Johnston, S. L., Caramori, G., Papi, A.

“…Background Asthma and other Th2 inflammatory conditions have been associated with increased susceptibility to viral infections. The mechanisms by which Th2…”
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Study of modifiable risk factors for asthma exacerbations: virus infection and allergen exposure increase the risk of asthma hospital admissions in children by Murray, C S, Poletti, G, Kebadze, T, Morris, J, Woodcock, A, Johnston, S L, Custovic, A

“…Background: Asthma exacerbation is the most common cause of hospital admission in children. A study was undertaken to investigate the importance of allergen…”
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Impaired innate interferon induction in severe therapy resistant atopic asthmatic children by Edwards, M R, Regamey, N, Vareille, M, Kieninger, E, Gupta, A, Shoemark, A, Saglani, S, Sykes, A, Macintyre, J, Davies, J, Bossley, C, Bush, A, Johnston, S L

“…Deficient type I interferon-β and type III interferon-λ induction by rhinoviruses has previously been reported in mild/moderate atopic asthmatic adults. No…”
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Respiratory virus induction of alpha-, beta- and lambda-interferons in bronchial epithelial cells and peripheral blood mononuclear cells by Khaitov, M.R, Laza-Stanca, V, Edwards, M.R, Walton, R.P, Rohde, G, Contoli, M, Papi, A, Stanciu, L.A, Kotenko, S.V, Johnston, S.L

“…Respiratory viruses, predominantly rhinoviruses are the major cause of asthma exacerbations. Impaired production of interferon-β in rhinovirus infected…”
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Febrile respiratory illnesses in infancy and atopy are risk factors for persistent asthma and wheeze by KUSEL, M. M. H, KEBADZE, T, JOHNSTON, S. L, HOLT, P. G, SLY, P. D

“…Severe viral respiratory illnesses and atopy are risk factors for childhood wheezing and asthma. The aim of this study was to explore associations between…”
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Viruses and bacteria in acute asthma exacerbations - A GA²LEN-DARE systematic review by Papadopoulos, N.G, Christodoulou, I, Rohde, G, Agache, I, Almqvist, C, Bruno, A, Bonini, S, Bont, L, Bossios, A, Bousquet, J, Braido, F, Brusselle, G, Canonica, G.W, Carlsen, K.H, Chanez, P, Fokkens, W.J, Garcia-Garcia, M, Gjomarkaj, M, Haahtela, T, Holgate, S.T, Johnston, S.L, Konstantinou, G, Kowalski, M, Lewandowska-Polak, A, Lødrup-Carlsen, K, Mäkelä, M, Malkusova, I, Mullol, J, Nieto, A, Eller, E, Ozdemir, C, Panzner, P, Popov, T, Psarras, S, Roumpedaki, E, Rukhadze, M, Stipic-Markovic, A, Todo Bom, A, Toskala, E, van Cauwenberge, P, van Drunen, C, Watelet, J.B, Xatzipsalti, M, Xepapadaki, P, Zuberbier, T

“…To cite this article: Papadopoulos NG, Christodoulou I, Rohde G, Agache I, Almqvist C, Bruno A, Bonini S, Bont L, Bossios A, Bousquet J, Braido F, Brusselle G,…”
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Rhinovirus exposure impairs immune responses to bacterial products in human alveolar macrophages by Oliver, B G G, Lim, S, Wark, P, Laza-Stanca, V, King, N, Black, J L, Burgess, J K, Roth, M, Johnston, S L

“…Rhinovirus infection is responsible for considerable morbidity and mortality as the major cause of exacerbations of asthma, and is also known to induce…”
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Takayasu arteritis: a review by Johnston, S L, Lock, R J, Gompels, M M

“…Takayasu arteritis is a well known yet rare form of large vessel vasculitis. This review details the history, clinical features, differential diagnoses,…”
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Lung function prior to viral lower respiratory tract infections in prematurely born infants by Drysdale, Simon B, Wilson, Theresa, Alcazar, Mireia, Broughton, Simon, Zuckerman, Mark, Smith, Melvyn, Rafferty, Gerrard F, Johnston, S L, Greenough, Anne

“…Prematurely born infants who develop respiratory syncytial virus (RSV) lower respiratory tract infections (LRTIs) have lung function abnormalities at…”
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CXC chemokines and antimicrobial peptides in rhinovirus-induced experimental asthma exacerbations by Rohde, G., Message, S. D., Haas, J. J., Kebadze, T., Parker, H., Laza-Stanca, V., Khaitov, M. R., Kon, O. M., Stanciu, L. A., Mallia, P., Edwards, M. R., Johnston, S. L.

“…Summary Rationale Rhinoviruses (RVs) are the major triggers of asthma exacerbations. We have shown previously that lower respiratory tract symptoms, airflow…”
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Neutrophil degranulation and cell lysis is associated with clinical severity in virus-induced asthma by Wark, P.A.B, Johnston, S.L, Moric, I, Simpson, J.L, Hensley, M.J, Gibson, P.G

“…Acute exacerbations of asthma are frequently caused by viral infections, but the inflammatory mechanisms in virus-induced asthma are poorly understood. The aim…”
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A defective type 1 response to rhinovirus in atopic asthma by Papadopoulos, N G, Stanciu, L A, Papi, A, Holgate, S T, Johnston, S L

“…Background: Rhinoviruses (RVs) are the most frequent precipitants of the common cold and asthma exacerbations, but little is known about the immune response to…”
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New year: new editors by Wedzicha, J A, Johnston, S L, Mitchell, D M

“…Research studies are also becoming more complex, frequently with many collaborators and larger data sets. [...]authors will now have the availability of an…”
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Lack of an exaggerated inflammatory response on virus infection in cystic fibrosis by KIENINGER, E, VAREILLE, M, EDWARDS, M. R, REGAMEY, N, KOPF, B. S, BLANK, F, ALVES, M. P, GISLER, F. M, LATZIN, P, CASAULTA, C, GEISER, T, JOHNSTON, S. L

“…Respiratory virus infections play an important role in cystic fibrosis (CF) exacerbations, but underlying pathophysiological mechanisms are poorly understood…”
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Clinical Immunology Review Series: An approach to the patient with recurrent superficial abscesses by Johnston, S.L

“…Patients may be referred to the immunology clinic for investigation of recurrent superficial abscess formation. In the majority of adult patients this clinical…”
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Pelvic floor dysfunction in midlife women by Johnston, S. L.

“…Pelvic floor dysfunction in women includes urinary incontinence and pelvic organ prolapse. In midlife, genitourinary atrophy is commonly associated with these…”
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Aetiological role of viral and bacterial infections in acute adult lower respiratory tract infection (LRTI) in primary care by Creer, D D, Dilworth, J P, Gillespie, S H, Johnston, A R, Johnston, S L, Ling, C, Patel, S, Sanderson, G, Wallace, P G, McHugh, T D

“…Background: Lower respiratory tract infections (LRTI) are a common reason for consulting general practitioners (GPs). In most cases the aetiology is unknown,…”
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Activated, Cytotoxic CD8+ T Lymphocytes Contribute to the Pathology of Asthma Death by O'SULLIVAN, S, CORMICAN, L, FAUL, J. L, ICHINOHE, S, JOHNSTON, S. L, BURKE, C. M, POULTER, L. W

“…This study investigates the presence of CD8(+) T lymphocytes and their possible association with viral infection in bronchi of victims of fatal asthma…”
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Rhinovirus infection and house dust mite exposure synergize in inducing bronchial epithelial cell interleukin-8 release by Bossios, A., Gourgiotis, D., Skevaki, C. L., Saxoni-Papageorgiou, P., Lötvall, J., Psarras, S., Karpathios, T., Constandopoulos, A. G., Johnston, S. L., Papadopoulos, N. G.

“…Summary Background Human rhinoviruses (HRVs) and house dust mites (HDMs) are among the most common environmental factors able to induce airway inflammation in…”
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Azithromycin induces anti-viral responses in bronchial epithelial cells by Gielen, V, Johnston, S L, Edwards, M R

“…The majority of asthma exacerbations are caused by rhinovirus. Currently the treatment of asthma exacerbations is inadequate. Previous evidence suggests that…”
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