Search Results - "ghieri, Fabio"
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The dynamic functions of IRF4 in B cell malignancies
Published in Clinical and experimental medicine (01-08-2023)“…The trajectory of B cell development goes through subsequent steps governed by complex genetic programs, strictly regulated by multiple transcription factors…”
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Genomic and clinical findings in myeloid neoplasms with PDGFRB rearrangement
Published in Annals of hematology (01-02-2022)“…Platelet-derived growth factor receptor B ( PDGFRB ) gene rearrangements define a unique subgroup of myeloid and lymphoid neoplasms frequently associated with…”
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Characterization of FLT3-ITDmut acute myeloid leukemia: molecular profiling of leukemic precursor cells
Published in Blood cancer journal (New York) (25-08-2020)“…Acute myeloid leukemia (AML) with FLT3 -ITD mutations ( FLT3 -ITD mut ) remains a therapeutic challenge, with a still high relapse rate, despite targeted…”
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Minimal/Measurable Residual Disease Monitoring in NPM1 -Mutated Acute Myeloid Leukemia: A Clinical Viewpoint and Perspectives
Published in International journal of molecular sciences (06-11-2018)“…Acute myeloid leukemia (AML) with gene mutations is currently recognized as a distinct entity, due to its unique biological and clinical features. We summarize…”
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Multiparametric Flow Cytometry for MRD Monitoring in Hematologic Malignancies: Clinical Applications and New Challenges
Published in Cancers (12-09-2021)“…Along with the evolution of immunophenotypic and molecular diagnostics, the assessment of Minimal Residual Disease (MRD) has progressively become a keystone in…”
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Nelarabine as salvage therapy and bridge to allogeneic stem cell transplant in 118 adult patients with relapsed/refractory T‐cell acute lymphoblastic leukemia/lymphoma. A CAMPUS ALL study
Published in American journal of hematology (01-12-2020)“…The outcome of relapsed or refractory (R/R) T‐cell acute lymphoblastic leukemia/lymphoma (T‐ALL/T‐LBL) in adults is poor, with less than 20% of patients…”
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Do high MICs predict the outcome in invasive fusariosis?
Published in Journal of antimicrobial chemotherapy (12-03-2021)“…Abstract Background Invasive fusariosis (IF) affects mostly severely immunocompromised hosts and is associated with poor outcome. Since Fusarium species…”
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Primary central nervous system diffuse large B-cell lymphoma (DLBCL) can rarely mimic an acute peripheral neuropathy
Published in Muscle & nerve (01-06-2016)Get full text
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Chromothripsis is a frequent event and underlies typical genetic changes in early T-cell precursor lymphoblastic leukemia in adults
Published in Leukemia (01-11-2022)“…Chromothripsis is a mitotic catastrophe that arises from multiple double strand breaks and incorrect re-joining of one or a few chromosomes. We report on…”
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Long–Standing evolution of paraneoplastic cerebellar degeneration in a diffuse large B-cell lymphoma
Published in Journal of the neurological sciences (15-01-2019)“…Highlights•Paraneoplastic cerebellar degeneration (PCD) is characterized by a pancerebellar ataxia with diplopia, nystagmus and dysarthria that might evolve…”
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How I treat HHV8/KSHV-related diseases in posttransplant patients
Published in Blood (15-11-2012)“…Posttransplantation human herpesvirus-8 (HHV8)/Kaposi sarcoma herpesvirus (KSHV) primary infection and/or reactivations are associated with uncommon and…”
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Blinatumomab differentially modulates peripheral blood and bone marrow immune cell repertoire: A Campus ALL study
Published in British journal of haematology (01-11-2023)“…Summary Blinatumomab is the first bi‐specific T‐cell engager approved for relapsed or refractory B‐cell precursor acute lymphoblastic leukaemia (B‐ALL)…”
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BCR-ABL–specific T-cell therapy in Ph+ ALL patients on tyrosine-kinase inhibitors
Published in Blood (02-02-2017)“…Although the emergence of bone marrow (BM)–resident p190BCR-ABL–specific T lymphocytes has been correlated with hematologic and cytogenetic remissions in…”
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NPM1 -Mutated Myeloid Neoplasms with <20% Blasts: A Really Distinct Clinico-Pathologic Entity?
Published in International journal of molecular sciences (26-11-2020)“…Nucleophosmin ( ) gene mutations rarely occur in non-acute myeloid neoplasms (MNs) with <20% blasts. Among nearly 10,000 patients investigated so far,…”
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Variability of Voriconazole Trough Levels in Haematological Patients: Influence of Comedications with cytochrome P450(CYP) Inhibitors and/or with CYP Inhibitors plus CYP Inducers
Published in Basic & clinical pharmacology & toxicology (01-06-2016)“…Voriconazole plasma exposure greatly varies among haematological patients. The purpose of this study was to identify the magnitude of influence of…”
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Antiviral prophylaxis to prevent herpes simplex virus (HSV) and varicella zoster virus (VZV) reactivation in adult patients with newly diagnosed acute leukemia: results of a survey submitted to Italian centers belonging to SEIFEM (Sorveglianza Epidemiologica Infezioni nelle Emopatie) group
Published in Annals of hematology (01-10-2024)Get full text
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