Voluntary pregnancy termination among women with HIV in the HAART era (2002-2008): a case series from a national study

There is limited information about the determinants of voluntary pregnancy termination (VPT) among women with HIV in the current context of wide access to highly active antiretroviral therapy (HAART). To investigate this issue, we analysed the characteristics of a series of VPTs which occurred in an...

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Bibliographic Details
Published in:	AIDS care Vol. 22; no. 1; pp. 50 - 53
Main Authors:	Floridia, Marco, Tamburrini, Enrica, Tibaldi, Cecilia, Anzidei, Gianfranco, Muggiasca, Maria Luisa, Meloni, Alessandra, Guerra, Brunella, Maccabruni, Anna, Molinari, Atim, Spinillo, Arsenio, Dalzero, Serena, Ravizza, Marina, for The Italian Group on Surveillance on Antiretroviral Treatment in Pregnancy
Format:	Journal Article
Language:	English
Published:	Abingdon Taylor & Francis Group 01-01-2010 Taylor & Francis Taylor & Francis Ltd Taylor & Francis (Routledge)
Subjects:	Abortion Abortion, Induced - trends Adult AIDS AIDS/HIV Anti-HIV Agents - therapeutic use Antiretroviral drugs Antiretroviral therapy Antiretroviral Therapy, Highly Active Attitude to Health Biological and medical sciences Case management CD4 Lymphocyte Count Drug therapy Female Fundamental and applied biological sciences. Psychology Gynecology and obstetrics HIV HIV Infections - drug therapy Human immunodeficiency virus Human viral diseases Humans Immune response system Infectious Disease Transmission, Vertical Infectious diseases Medical sciences Pregnancy Pregnancy Complications, Infectious - drug therapy pregnancy termination Pregnant women Prevention Psychology and medicine Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Women Italy Europe Social environment Antiretroviral agent abortion Pharmacotherapy Maternal diseases Antiviral Woman Public health Human Immunopathology Drug combination Observational study Induced abortion Retroviridae AIDS Immune deficiency Lentivirus pregnancy termination Infection Virus Pregnancy Treatment HIV Viral disease Human immunodeficiency virus women Life Sciences
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Summary:	There is limited information about the determinants of voluntary pregnancy termination (VPT) among women with HIV in the current context of wide access to highly active antiretroviral therapy (HAART). To investigate this issue, we analysed the characteristics of a series of VPTs which occurred in an ongoing observational national study of pregnant women with HIV between 2002 and 2008. Sixty-three cases of VPT were compared with 334 pregnancies not ending in a VPT concurrently reported from the same centres. VPTs showed significant associations with unplanned pregnancy (odds ratio [OR]: 24.3; 95% confidence interval [CI]: 5.8-101.2), previous pregnancies reported to the study (OR: 2.5; 95% CI: 1.30-4.82), lower CD4 counts (270 vs. 420 cells/mm 3 ), and HIV-infected current partner (OR: 1.88; 95% CI: 0.97-3.63). Our data indicate that there is still the need to improve pregnancy planning among women with HIV, and strongly suggest that interventions aimed at improving pregnancy planning might also reduce the occurrence of VPT. Women with low CD4 counts and those with an HIV-infected partner represent two groups that should receive particular attention in preventive strategies.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-Feature-1
ISSN:	0954-0121 1360-0451
DOI:	10.1080/09540120903033268